An official website of the United States government
Here’s how you know
Official websites use .gov
A .gov website belongs to an official government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.
Zack Buck, Newell Moser, May Ling Martin, Nicholas Derimow, Damian Lauria, Enrico Lucon, Douglas Stalheim, Peter Bradley, Matthew Connolly
Hydrogen is known to cause premature failure in various steel infrastructures due to effects of embrittlement, which is particularly detrimental to ferritic steel structures such as pipelines and pressure vessels. Therefore, understanding the
Clay Davis, Antonio Possolo, Stefanie Trapmann, Stephen L.R. Ellison, Angelique Botha, Jiang Zheng
The number of reference materials (RMs), including certified reference materials (CRMs) with assigned or certified qualitative properties, has steadily increased in recent years. In response, the Technical Committee for Reference Materials of the
Sofia Sotiriadou, Eleftheria Ntonti, Marc Assael, Richard A. Perkins, Marcia L. Huber
This paper presents new wide-ranging correlations for the viscosity of ethene based on critically evaluated experimental data. The viscosity correlation is valid from the triple point to 580 K and up to 195 MPa pressure. The average absolute percentage
Janathan Campbell, Neil Almond, Y Bae, Ravneet Bhuller, Andrea Briones, S-Y CHO, Megan Cleveland, Thomas Cleveland, Francis Galaway, Hua-Jun He, U Herbrand, Jim Huggett, Sarah Kempster, Ibolya Kepiro, Afifa Khan, Edward Kwee, Wilson Li, Sheng Lin-Gibson, Luise Luckau, Caterina Minelli, M Ryadnov, I Searing, Lili Wang, Alexandra Whale, Julian Braybrook
Viral vectors are agents enabling gene transfer and genome editing and have widespread utility across the healthcare and biotechnology sectors. In January 2023, the International Bureau for Weights and Measures' Consultative Committee for Amount of
Debra Ellisor, Amanda Moors, Jennifer Hoguet, Jennifer Ness, Amanda Capuano, Olivia Franco
The Biospecimen Science Group at the National Institute of Standards and Technology (NIST) Biorepository has been responsible for the curation, maintenance, and preparation of biological specimens at cryogenic temperatures since 2002. The team's expertise
Michael F. Link, Rileigh Robertson, Andrew Shore, Behrang Hamadani, Christina Cecelski, Dustin Poppendieck
Devices using 222 nm germicidal ultraviolet light (GUV222) have been marketed to reduce virus transmission indoors with low risk of occupant harm from direct UV exposure. GUV222 generates ozone, an indoor air pollutant and oxidant, under constrained
David Pamies, Jason Ekert, Marie-Gabrielle Zurich, Olivier Frey, Sophie Werner, MONICA PIERGIOVANNI, Benjamin Freedman, Adrian Keong, Darwin Reyes-Hernandez, Hendrik Erfurth, Peter Loskill, Pelin Candarlioglu, Shan Wang, Thomas Hartung, Sandra Coecke, Glyn Stacey, Marcel Leist
Cell culture technology has seen great innovations and progress in the 21st centuryClassical single-cell and monolayer models have been replaced by more complex 3D models (e.g., reaggregates, spheroids, organoids) to improve the predictivity of in vitro
Michael F. Link, Rileigh Robertson, Dustin Poppendieck
In response to the COVID-19 pandemic, air cleaning technologies were promoted as useful tools for disinfecting public spaces and combating airborne pathogen transmission. However, no standard method exists to assess potentially harmful byproduct formation
In this letter we examine the organization of the traditional base units and defining constants established in the 2019 redefinition of the international system of units (SI). For the next redefinition of the SI, which will accompany the anticipated
Benjamin Standfield, Eric Holterfield, Russell Waddell
Among the chief topic areas of Industry 4.0, digital thread technology offers the opportunity for increased productivity, efficiency, and traceability throughout a product's lifecycle. While the basic concept of digital thread is easy to realize by
Greta Babakhanova, Carl Simon Jr., Eugenia Romantseva
Biofabricated tissue-engineered constructs have the potential to transform personalized medicine. However, characterizing these constructs post-fabrication and throughout preclinical use remains challenging. On December 1, 2022, the National Institute of
Carl Simon Jr., Anne L. Plant, Catherine Zander, Erich Bozenhardt, Christina Celluzzi, David Dobnik, Melanie Grant, John Hughes, Uma Lakshmipathy, Kok-Seong Lim, Laura Montgomery, Hesham Nawar, Thiana Nebel, Linda Peltier, James Sherley, Rouzbeh Taghizadeh, Eddie Tan, Sandrine Vessillier
One of the most challenging aspects of cell and gene therapy products (CGTPs) is defining mechanism of action (MOA), potency and efficacy of the product. This perspective examines these concepts and presents helpful ways to think about them through the
Katrice Lippa, Jan Konijnenburg, Loren Minnich, Tanvi Pandya, James Willis
Every day, overweight and excessively heavy vehicles cause damage to roads, bridges, and other vehicle-based infrastructure. To protect this vital transportation infrastructure for the U.S., states have imposed weight limits for commercial and fleet
John McGuire, David Sefcik, Lisa Warfield, Yvonne Branden, Katrice Lippa
NIST Handbook 130 includes a compilation of model laws and regulations and related interpretations and guidelines designed to encourage uniformity in adoption and implementation of weights and measures laws and regulations. The model laws and regulations
In FY 2022, the 22 federal agencies that reported did not add or rescind any GUS in lieu of VCS, leaving a total of 80 previously reported GUS in lieu of VCS still in use. This analysis does not reflect the use of standards by the Department of Defense
In digital forensics, file system analysis is a precursor task to event reconstruction. Often, unallocated content within a file system is content of interest to an investigation, and thus recognition, extraction, and ascription of unallocated files are
Alexander Kuan, Kareem Aggour, Shengyen Li, Yan Lu, Luke Mohr, Alex Kitt, Hunter Macdonald
Additive manufacturing (AM) leverages emerging technologies and well-adopted processes to produce near-net-shape products. The advancement of AM technology requires data management tools to collect, store and share information through the product
Darwin Reyes-Hernandez, Mandy Esch, Lorna Ewart, Rohollah Nasiri, Anna Herland, Carolina Lucchesi, Kyung Sung, MONICA PIERGIOVANNI, Jelena Vukasinovic, James Shoemaker, Nureddin Ashammakhi
Limitations with cell cultures and experimental animal-based studies have had the scientific and industrial communities searching for new approaches that can provide reliable human models for applications such as drug development, toxicological assessment
Apparent negative crack growth is often encountered when performing elastic-plastic fracture toughness tests with the Elastic Compliance single-specimen technique. It consists of a decrease of specimen compliance (reduction of crack size) during the early
Marla L. Dowell, Hannah Brown, Gretchen Greene, Paul D. Hale, Brian Hoskins, Sarah Hughes, Bob R. Keller, R Joseph Kline, June W. Lau, Jeff Shainline
The CHIPS and Science Act of 2022 called for NIST to "carry out a microelectronics research program to enable advances and breakthroughs....that will accelerate the underlying R&D for metrology of next-generation microelectronics and ensure the
Thomas W. Vetter, Colleen E. Bryan Sallee, Brian Lang, Anthony F. Marlow, Jennifer Ness, Rick L. Paul, Adam L. Pintar, Bruce Scruggs, Nicholas Sharp, Maria Isabel Vega Martinez, John Sieber
Standard Reference Material (SRM) 2693a Bituminous Coal (Nominal Mass Fraction 0.5 % Sulfur) is intended for use in the evaluation of techniques employed in the determination of sulfur, mercury, chlorine, and ash in coal and materials of a similar matrix
We present the long-term timing accuracy of STL receivers by validating their performance against UTC(NIST), the timing reference at the National Institute of Standards and Technology (NIST), for a duration of 100 days. STL is a mature timing and location
Standard Reference Materia® (SRM®) 2246a Relative Intensity Correction Standard for Raman Spectroscopy: 830 nm Excitation is intended for use in the correction of the relative intensity of Raman spectra obtained with Raman instruments employing 830 nm
Eleftheria Ntonti, Sofia Sotiriadou, Marc Assael, Marcia L. Huber, Boris Wilthan, Manabu Watanabe
The available experimental data for the density, thermal conductivity, and viscosity of liquid titanium, zirconium, hafnium, vanadium, niobium, tantalum, chromium, molybdenum, and tungsten have been critically examined with the intention of establishing
To advance the additive manufacturing (AM) technologies, R&D projects may evaluate new facilities and different processes that need a scalable data architecture to accommodate the progressing knowledge. This work introduces a data pedigree to enable the