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Displaying 51 - 75 of 823

Optimizing Wastewater Surveillance: The Necessity of Standardized Reporting and Proficiency for Public Health

August 7, 2024
Author(s)
Ishi Keenum, Nancy Lin, Alshae Logan, Adam Gushgari, Nishita D'Souza4, Joshua Steele, Devrim Kaya, Lydia Gushgari
Wastewater-based surveillance (WBS) has emerged as a valuable tool for public health, allowing a greater understanding of disease prevalence in communities. With historical significance in monitoring polio transmission,1 WBS gained further prominence in

Global Community Technology Challenge (GCTC) Strategic Plan 2024-2026

June 28, 2024
Author(s)
Michael Dunaway, Thomas Roth, Edward Griffor, David A. Wollman
This document provides a strategy and a project plan for the Global Community Technology Challenge, a federal smart cities program led by the Smart Connected Systems Division at the National Institute of Standards and Technology, an agency of the U.S

Certification of Standard Reference Material(R) 1955a Homocysteine in Frozen Human Serum

June 21, 2024
Author(s)
Carolyn Burdette, Elena Wood, Jerome Mulloor, Michael Nelson, Blaza Toman, Aaron Urbas
Standard Reference Material (SRM) 1955a Homocysteine in Frozen Human Serum is intended for use in validating homocysteine measurement procedures used by in vitro diagnostics manufacturers, reference laboratories, and clinical laboratories in the United

Assessing girth weld quality of pipeline steels and their susceptibility to hydrogen embrittlement

June 16, 2024
Author(s)
Zack Buck, Newell Moser, May Ling Martin, Nicholas Derimow, Damian Lauria, Enrico Lucon, Douglas Stalheim, Peter Bradley, Matthew Connolly
Hydrogen is known to cause premature failure in various steel infrastructures due to effects of embrittlement, which is particularly detrimental to ferritic steel structures such as pipelines and pressure vessels. Therefore, understanding the

Standards and Metrology for Viral Vectors as Molecular Tools: Outcomes from a CCQM Workshop

May 24, 2024
Author(s)
Janathan Campbell, Neil Almond, Y Bae, Ravneet Bhuller, Andrea Briones, S-Y CHO, Megan Cleveland, Thomas Cleveland, Francis Galaway, Hua-Jun He, U Herbrand, Jim Huggett, Sarah Kempster, Ibolya Kepiro, Afifa Khan, Edward Kwee, Wilson Li, Sheng Lin-Gibson, Luise Luckau, Caterina Minelli, M Ryadnov, I Searing, Lili Wang, Alexandra Whale, Julian Braybrook
Viral vectors are agents enabling gene transfer and genome editing and have widespread utility across the healthcare and biotechnology sectors. In January 2023, the International Bureau for Weights and Measures' Consultative Committee for Amount of

Homogenization of Large Batch Frozen Materials Using the Palla-VM-KT Vibrating Mill

May 21, 2024
Author(s)
Debra Ellisor, Amanda Moors, Jennifer Hoguet, Jennifer Ness, Amanda Capuano, Olivia Franco
The Biospecimen Science Group at the National Institute of Standards and Technology (NIST) Biorepository has been responsible for the curation, maintenance, and preparation of biological specimens at cryogenic temperatures since 2002. The team's expertise

Ozone generation and chemistry from 222 nm germicidal ultraviolet light in a fragrant restroom

May 20, 2024
Author(s)
Michael F. Link, Rileigh Robertson, Andrew Shore, Behrang Hamadani, Christina Cecelski, Dustin Poppendieck
Devices using 222 nm germicidal ultraviolet light (GUV222) have been marketed to reduce virus transmission indoors with low risk of occupant harm from direct UV exposure. GUV222 generates ozone, an indoor air pollutant and oxidant, under constrained

Recommendations on fit-for-purpose criteria to establish a quality management for microphysiological systems (MPS) and for monitoring of their reproducibility

May 14, 2024
Author(s)
David Pamies, Jason Ekert, Marie-Gabrielle Zurich, Olivier Frey, Sophie Werner, MONICA PIERGIOVANNI, Benjamin Freedman, Adrian Keong, Darwin Reyes-Hernandez, Hendrik Erfurth, Peter Loskill, Pelin Candarlioglu, Shan Wang, Thomas Hartung, Sandra Coecke, Glyn Stacey, Marcel Leist
Cell culture technology has seen great innovations and progress in the 21st centuryClassical single-cell and monolayer models have been replaced by more complex 3D models (e.g., reaggregates, spheroids, organoids) to improve the predictivity of in vitro

A proposal for three categories of units within the SI

April 29, 2024
Author(s)
John Lehman, Alan Migdall, Julia Scherschligt
In this letter we examine the organization of the traditional base units and defining constants established in the 2019 redefinition of the international system of units (SI). For the next redefinition of the SI, which will accompany the anticipated

Spatial and Temporal Data Alignment from Disparate Sources for Feature Association

April 25, 2024
Author(s)
Benjamin Standfield, Eric Holterfield, Russell Waddell
Among the chief topic areas of Industry 4.0, digital thread technology offers the opportunity for increased productivity, efficiency, and traceability throughout a product's lifecycle. While the basic concept of digital thread is easy to realize by

Mechanism of Action, Potency and Efficacy: Considerations for Cell and Gene Therapies

April 1, 2024
Author(s)
Carl Simon Jr., Anne L. Plant, Catherine Zander, Erich Bozenhardt, Christina Celluzzi, David Dobnik, Melanie Grant, John Hughes, Uma Lakshmipathy, Kok-Seong Lim, Laura Montgomery, Hesham Nawar, Thiana Nebel, Linda Peltier, James Sherley, Rouzbeh Taghizadeh, Eddie Tan, Sandrine Vessillier
One of the most challenging aspects of cell and gene therapy products (CGTPs) is defining mechanism of action (MOA), potency and efficacy of the product. This perspective examines these concepts and presents helpful ways to think about them through the

Certification Approaches for Weigh-In-Motion Systems in Law Enforcement Applications

March 26, 2024
Author(s)
Katrice Lippa, Jan Konijnenburg, Loren Minnich, Tanvi Pandya, James Willis
Every day, overweight and excessively heavy vehicles cause damage to roads, bridges, and other vehicle-based infrastructure. To protect this vital transportation infrastructure for the U.S., states have imposed weight limits for commercial and fleet

A Common Data Dictionary and Common Data Model for Additive Manufacturing

February 16, 2024
Author(s)
Alexander Kuan, Kareem Aggour, Shengyen Li, Yan Lu, Luke Mohr, Alex Kitt, Hunter Macdonald
Additive manufacturing (AM) leverages emerging technologies and well-adopted processes to produce near-net-shape products. The advancement of AM technology requires data management tools to collect, store and share information through the product
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