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Certification of Standard Reference Material® 1955a Homocysteine in Frozen Human Serum



Carolyn Burdette, Elena Wood, Jerome Mulloor, Michael Nelson, Blaza Toman, Aaron Urbas


Standard Reference Material (SRM) 1955a Homocysteine in Frozen Human Serum is intended for use in validating homocysteine measurement procedures used by in vitro diagnostics manufacturers, reference laboratories, and clinical laboratories in the United States and globally. A unit of SRM 1955a consists of three vials of frozen human serum, each of a different homocysteine concentration. This publication documents the production, analytical methods, and computations involved in characterizing this product.
Special Publication (NIST SP) - 260-247
Report Number


Homocysteine, Isotope Dilution Liquid Chromatography Mass Spectrometry (ID LC-MS), Reference Measurement Procedure (RMP), Standard Reference Material (SRM).


Burdette, C. , Wood, E. , Mulloor, J. , Nelson, M. , Toman, B. and Urbas, A. (2024), Certification of Standard Reference Material® 1955a Homocysteine in Frozen Human Serum, Special Publication (NIST SP), National Institute of Standards and Technology, Gaithersburg, MD, [online],, (Accessed July 20, 2024)


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Created June 21, 2024, Updated June 27, 2024