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Health

Pharmaceuticals

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Displaying 101 - 122 of 122

Recent Advances in Electrochemical Glyco-biosensing

April 8, 2011
Author(s)
Rebecca A. Zangmeister, Germarie Sanchez-Pomales
Biosensors based on electrochemical transduction mechanisms have recently made advances into the field of glycan analysis. These glyco-biosensor assays offer simple, rapid, sensitive and economical approaches to the measurement need for rapid glycan

Combined scanning probe and light scattering characterization of multi-stage self-assembly of targeted liposome-based delivery systems

December 21, 2010
Author(s)
Natalia Farkas, John A. Dagata, Chengli Yang, Antonina Rait, Kathleen Pirollo, Esther Chang
The mean size and size distribution of a targeted nanoparticle delivery system (NDS) strongly influences the intrinsic stability and functionality of this molecular complex, affects its performance as a systemic drug delivery platform, and ultimately

Fluorinated Copolymer Nanoparticles for Multimodal Imaging Applications

February 18, 2010
Author(s)
Mark M. Bailey, Christine M. Mahoney, Elodie Dempah, Jeffrey M. Davis, Matthew Becker, Supang Khondee, Eric J. Munson, Cory J. Berkland
Nanomaterials have emerged as valuable tools in biomedical imaging techniques, such as magnetic resonance imaging (MRI), fluorescence, positron emission tomography (PET), and others. Some have been designed to serve as multimodal imaging agents, combining

Isolation, Purification, and Full NMR Assignments of cyclopamine from Veratrum californicum

June 24, 2009
Author(s)
Daniel W. Bearden, John E. Oatis, Pam Brunsfeld, James W. Rushing, Peter D. Moeller, Thomas N. Gallien, George W. Cooper
The Hedgehog (Hh) signaling pathway is essential for embryogenesis and tissue homeostasis in the adult. However, it may also induce malignancies in a number of tissues when constitutively activated, and it also may have a role in other forms of normal and

Solid State Chemistry of Proteins: II. The Correlation of Storage Stability of Freeze-Dried Human Growth Hormone (hGH) With Structure and Dynamics in the Glassy Solid

December 1, 2008
Author(s)
Michael Pikal, Daniel Rigsbee, Michael L. Roy, Dawn Galreath, Karl J. Kovach, Bingquan S. Wang, John Carpenter, Marcus T. Cicerone
This research presents storage stability of human growth hormone, hGH, in a variety of lyophilized formulations, including systems of varying sugar:hGH weight ratios for both sucrose and trehalose. Stability was assessed at multiple time points during

Cold Chain Storage of Vaccines: A Brief Introduction to Thermometry

September 1, 2008
Author(s)
Dean C. Ripple
To maintain the efficacy of vaccines requires maintaining the storage temperature within well-defined limits; vaccine failure due to improper storage results in large direct and indirect public health costs. In this presentation, I give a brief

Color Test Reagents/Kits for Preliminary Identification of Drugs of Abuse

July 1, 2000
Author(s)
Alim A. Fatah
The objective of this standard is to establish minimum requirements for color test reagent/kits to detect drugs. It is applicable to field testing kits that consist of color reagents for the preliminary identification of drugs. It does not apply to kits
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