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Chemistry

Molecular characterization

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Displaying 26 - 50 of 178

Glycosylation and the global virome

October 10, 2022
Author(s)
Cassandra Pegg, Benjamin Schulz, Ben Neely, Gregory Albery, Colin Carlson
The sugars that coat the outsides of viruses and host cells are key to successful disease transmission, but they remain understudied compared to other molecular features. Understanding the comparative zoology of glycosylation - and harnessing it for

Mass Spectral Library Methods for Analysis of Site-Specific N-Glycosylation: Application to Human Milk Proteins

September 16, 2022
Author(s)
Concepcion Remoroza, Meghan Burke Harris, Xiaoyu (Sara) Yang, Sergey Sheetlin, Yuri Mirokhin, Sanford Markey, Dmitrii V. Tchekhovskoi, Stephen E. Stein
We present a mass-spectral library-based method for analyzing site-specific N-linked protein glycosylation. Its operation and utility are illustrated by applying it to both newly measured and available proteomics data of human milk glycoproteins. It

In-situ studies of the swelling by electrolyte in the electrochemical doping of an ethylene glycol substituted polythiophene

June 13, 2022
Author(s)
Lee J. Richter, Lucas Flagg, Lauren Asselta, Nicholas D'Antona, Natalie Stingelin, Tommaso Nicolini, Jonathan Onorato, Christine Luscombe, Ruipeng Li
Organic mixed ionic electronic conductors (OMIECs) have the potential to enable diverse new technologies, ranging from biosensors to flexible energy storage devices and neuromorphic computing platforms. However, study of these materials in their operating

Imaging 3D molecular orientation by orthogonal-pair polarization IR microscopy

February 28, 2022
Author(s)
Shuyu Xu, Chad R. Snyder, Jeremy Rowlette, Young Jong Lee
Anisotropic molecular alignment occurs ubiquitously and often heterogeneously in three dimensions (3D). However, conventional imaging approaches based on polarization can map only molecular orientation projected onto the 2D polarization plane. Here, an

Separations by Shape: Molecular Shape Recognition in Liquid Chromatography

February 28, 2022
Author(s)
Lane C. Sander
Molecular shape can provide a basis for chromatographic separations that is distinct from other interaction mechanisms often considered in liquid chromatography. Molecular shape recognition, or shape selectivity, is most evident for the separation of
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