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Camille Lombard-Banek, Kerstin Pohl, Edward Kwee, John T. Elliott, John E. Schiel
Mass Spectrometry (MS)-based proteomic measurements are uniquely poised to impact the development of cell and gene therapies. With the adoption of rigorous instrumental performance controls (PQs), large-scale proteomics can move from a research to a
Therapeutic monoclonal antibodies (mAbs) contain a variety of amino acids that are susceptible to enzymatic, chemical, and physical modifications. These modifications can happen throughout production, purification, formulation, and storage and many are
Katrice Lippa, William Davis, Christina Jones, Tracey Schock, Juan Aristizabal-Henao, Richard Beger, John Bowden, Corey Broeckling, Chris Beecher, Warwick Dunn, Roberto Flores, Goncalo Gouveia, Thomas Hartung, Matthew Lewis, Ioanna Ntai, Andrew Percy, Dan Raftery, Jinchun Sun, Georgios Theodoridis, Fariba Tayyari, Federico Torta, Candice Ulmer, Baljit Ubhi
Introduction The metabolomics quality assurance and quality control consortium (mQACC) is enabling the identification, development, prioritization and promotion of suitable reference materials (RMs) to be used in quality assurance (QA) and quality control
Now in its sixth decade, size-exclusion chromatography (SEC) remains the premier method by which to determine the molar mass averages and distributions of natural and synthetic macromolecules. Aided by its coupling to a variety and multiplicity of
Coherent anti-Stokes Raman scattering (CARS) microscopy is a label-free chemical imaging modality capable of interrogating local molecular composition, concentration, and even orientation. In comparison to traditional Raman spectroscopy/imaging, CARS
Young Jong Lee, Shuyu Xu, Chad R. Snyder, Jeremy Rowlette
The 3D molecular orientations of polymer chains are imaged and compared for a quiescent spherulite region and a shear deformed region of a semicrystalline poly(e-caprolactone) (PCL) film. The images of 3D orientation are acquired by a newly developed
Dianne L. Poster, Matthew Hardwick, C Cameron Miller, Michael A. Riley, W. W. Shanaka I. Rodrigo, Andras E. Vladar, John D. Wright, Christopher D. Zangmeister, Clarence Zarobila, Jeremy Starkweather, John Wynne, Jason Yilzarde
Data for interpreting virus inactivation on N95 face filtering respirators (FFRs) by ultraviolet (UV) radiation are important in developing UV strategies for N95 FFR disinfection and reuse for any situation, whether it be everyday practices, contingency
Zhengwei Wang, Kevin O'Dwyer, Ryan Muddiman, Tomas Ward, Charles Camp, Bryan Hennelly
Rapid label-free spectroscopy of biological and chemical specimen via molecular vibration through means of Broadband Coherent Anti-Stokes Raman Scattering (B-CARS) could serve as a basis for a robust diagnostic platform for a wide range of applications. A
Molecular shape can provide a basis for chromatographic separations that is distinct from other interaction mechanisms often considered in liquid chromatography. Molecular shape recognition, or shape selectivity, is most evident for the separation of
Christina Cecelski, George C. Rhoderick, Antonio Possolo, Jennifer Carney, Miroslav Vokoun, Jitka Privoznikova, Sangil Lee, Ji Hwan Kang, Yong Doo Kim, Dal Ho Kim, Tatiana Mace, Christophe Sutour, Celine Pascale, Napo Ntsasa, James Tshilongo, Mudalo Jozela, Nompumelelo Leshabane, Goitsemang Lekoto, David Worton, Paul Brewer, Fred Farrow-Dunn, Sergi Moreno, Klaus Wirtz, Volker Stummer, L.A. Konopelko, A.V. Kolobova, Y.A. Kustikov, A.Y. Klimov, O.V. Efremova, Janneke van Wijk, Adriaan van der Veen
The CCQM-K10.2018 comparison aimed to evaluate the capabilities of national metrology institutes (NMIs) to prepare and/or value assign primary reference mixtures containing benzene, toluene, ethylbenzene, p-xylene, m-xylene and o-xylene (subsequently
Antonio Montoro Bustos, Karen E. Murphy, Michael R. Winchester
Single particle inductively coupled plasma-mass spectrometry (spICP-MS) is an emerging technique that is capable of simultaneous measurement of size and number concentration of metal-containing nanoparticles (NPs) at environmentally relevant levels
Christina Cecelski, Kimberly Harris, Cassie Goodman, William A. Kimes, Philip Liu, Walter R. Miller Jr., Jennifer Carney
The Gas Sensing Metrology Group at NIST provides accurate, stable gaseous standards for use in various types of emissions testing and environmental monitoring. The group develops and maintains the highest level of primary gas standards, which provide
Xiao Ma, Georges Pavlidis, Eoghan Dillon, Victoria Beltran, Jeffrey Schwartz, Mathieu Thoury, Ferenc Borondics, Christophe Sandt, Kevin Kjoller, Barbara Berrie, Andrea Centrone
The formation and aggregation of metal carboxylates (metal-soaps) can degrade the appearance and integrity of oil paints and frequently poses a challenge to the conservation of painted works of art. Efforts to understand the root cause of metal-soap