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Bioscience

Biomaterials

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Displaying 301 - 325 of 3439

Mechanosensitive ion permeation across sub-nanoporous MoS2 monolayers

January 23, 2019
Author(s)
Alta Y. Fang, Kenneth Kroenlein, Alex Smolyanitsky
We use all-atom molecular dynamics simulations informed by density functional theory calculations to investigate aqueous ion transport across subnanoporous monolayer molybdenum disulfide (MoS2) membranes subject to varying tensile strains. Driven by a

Combinatorial Cassettes for Higher-Throughput Screening of Osteogenesis

October 4, 2018
Author(s)
Carl G. Simon Jr., Subhadip Bodhak, Hariharan K. Iyer, Luis Fernandez de Castro Diaz, Pam Robey, Azusa Maeda, Sergei Kuznetsov
Animal models are the most biologically relevant method for measuring the osteogenic capability of bone graft formulations. However, animal experiments are slow, tedious and the results can be highly variable, even when conducted within the same lab. In

Nanoscale Hygromechanical Behavior of Lignin

September 22, 2018
Author(s)
Kristen M. Hess, Jason Killgore, Wil Srubar
The nanoscale hygromechanical behavior of lignin is presented in this work. Three atomic force microscopy experimental methods were used to correlate moisture sorption of lignin to its mechanicalbehavior. First, sorption isotherms were established using

Hierarchical Cellulose Nanocrystal Blends for Bioinspired Damage Tolerant Photonic Films

May 4, 2018
Author(s)
Bharath NMN Natarajan, Ajay Krishnamurthy, Caglar Dogu Emiroglu, Amanda L. Forster, E. J. Foster, Christoph Weder, Douglas M. Fox, Jan Obrzut, Jeffrey W. Gilman
Attempts to emulate strong and tough natural composites using wood cellulose nanocrystals (CNCs) fall short in mechanical performance due to the low shear transfer ability of CNC interfaces in their helicoidal ensembles. This shortcoming is ascribed to the

Cholesterol Functionalized Aliphatic N-Substituted 8 Membered Cyclic Carbonate

April 10, 2018
Author(s)
Vivek M. Prabhu, Shrinivas Venkataraman, Kenneth Mineart, James Hedrick, Yi Yan Yang
Straightforward synthesis of cholesterol functionalized aliphatic N-substituted 8 membered cyclic carbonate monomer is reported. Well-defined PEGylated diblock copolymers were readily accessed via organo catalytic ring opening polymerization. These block

The Evolution of Polystyrene as a Cell Culture Material: A Brief History

April 10, 2018
Author(s)
Max J. Lerman, Josephine Lembong, Shinichiro Muramoto, John G. Gillen, John P. Fisher
Polystyrene (PS) has brought in vitro cell culture from its humble beginnings to the modern era, propelling dozens of research fields along the way. This review discusses the development of the material, fabrication, and treatment approaches to create the

The NISTmAb Reference Material 8671 Value Assignment, Homogeneity, and Stability

March 1, 2018
Author(s)
John E. Schiel, Abigail Turner, Catherine A. Mouchahoir, Katharina S. Yandrofski, Srivalli Telikepalli, Jason King, Paul C. DeRose, Dean C. Ripple, Karen W. Phinney
The NISTmAb Reference Material (RM) 8671 is intended to be the common industry standard monoclonal antibody for pre-competitive research in harmonizing current state-of-the-art technology and designing next generation characterization technologies for
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