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Tracey Schock (Fed)

Tracey's research interests have focused on the intimate cyclic relationship of oceans and humans. Her backgrounds in marine science and molecular biology followed by a shift to marine natural products chemistry (dissertation work) have facilitated a seamless transition into her current research emphasis at NIST in the field of environmental metabolomics.

Metabolomics research is a quickly growing field with broad application and a likely long-lived future for the measure of physiology or health in real time. Tracey is applying this technique to investigate effects of environmental stressors, such as chemical exposure, disease and/or abiotic changes like rise of sea water temperature, which offers the opportunity to assess systematic responses at the organismal level. The research may result in identification of novel biochemistry, potential markers of stress, information about stressor mechanisms of action, and ultimately a monitoring tool for the health of the environment. The lab has conducted metabolomics studies on a variety of conditions and organisms including oxidative stress in crustaceans, temperature effect in the coral pathogen Vibrio coralliilyticus, alternative diets for aquaculture species, and illness in green sea turtles. Nuclear magnetic resonance (NMR) has been the primary analytical platform for these analyses with immediate plans for LC/MS-based analyses in upcoming studies.

Tracey's research has an overarching aim of promoting best practices to produce high quality metabolomics data which includes stringent experimental designs, efficient and repeatable metabolite extraction, and reproducible metabolite measurements. Her current metabolomic studies include health assessments of samples collected and banked with the Pacific Islands team of the NIST Marine Environmental Specimen Bank and toxicology studies with sentinel species

Membership and Professional Activities

  • Metabolomics Society
  • Society of Environmental Toxicology and Chemistry (SETAC)
  • American Chemical Society
  • Adjunct Appointments
    - The College of Charleston
    - The Medical University of South Carolina

Publications

Best practices in NMR metabolomics: Current state

Author(s)
Tracey Schock, Amanda Bayless, Goncalo Gouveia, Robert Powers, Valerie Copie, John Cort, Hamid R. Eghbalnia, Wimal Pathmasiri, David S Wishart, Erik Andersson, Robert Brua, Leo Cheng, Chaevien Clendinen, Darcy Cochran, Alexandra Crook, Michah Jeppesen, Amith Maroli, Matthew Merritt, Heidi Roth, Isin Sakallioglu, Saurav Sarma, Lloyd Sumner, Panteleimon Takis, Mario Uchimiya
A literature survey was conducted to identify current practices used by NMR metabolomics investigators. A total of 463 papers from 2020 and 80 papers from 2010
Created August 15, 2019, Updated December 8, 2022