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Search Publications by: Tracey Schock (Fed)

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Displaying 1 - 25 of 34

Metabolomics 2023 Workshop Report: Moving Toward Consensus on Best QA/QC Practices in LC-MS-Based Untargeted Metabolomics

July 9, 2024
Author(s)
Tracey Schock, Jonathan Mosley, Warwick Dunn, Julia Kuligowski, Matthew Lewis, Maria Monge, Candice Ulmer Holland, Dajana Vuckovic, Krista Zanetti
Introduction: During the Metabolomics 2023 conference, the Metabolomics Quality Assurance and Quality Control Consortium (mQACC) presented a workshop focusing on key quality assurance and quality control (QA/QC) topic categories for LC-MS-based untargeted

Perspective: use and reuse of NMR-based metabolomics data: what works and what remains challenging

March 13, 2024
Author(s)
Tracey Schock, Goncalo Gouveia, Thomas Head, Leo L. Cheng, Chaevian Clendinen, John Cort, Xiuxia Du, Edison Arthur, Candace Fleischer, Jeffrey C. Hoch, Nathaniel Mercaldo, Wimal Pathmasiri, Daniel Raftery, Lloyd Sumner, Panteleimon Takis, Valerie Copie, Hamid R. Eghbalnia, Robert Powers
The National Cancer Institute (NCI) issued a Request for Information (RFI) in October 2022, soliciting input on using and reusing metabolomics data. This RFI aimed to seek input on best practices for metabolomics data storage, management, and use/reuse. In

Establishing a framework for best practices for quality assurance and quality control in untargeted metabolomics

February 12, 2024
Author(s)
Tracey Schock, Jonathan Mosley, Chris Beecher, Warwick Dunn, Julia Kuligowski, Matthew Lewis, Georgios Theodoridis, Candice Ulmer, Dajana Vuckovic, Ian Wilson, Krista Zanetti
Background: Quality assurance (QA) and quality control (QC) practices are key tenets that facilitate study and data quality across all applications of untargeted metabolomics. Such important practices will strengthen this field and accelerate its success

Best practices in NMR metabolomics: Current state

December 12, 2023
Author(s)
Tracey Schock, Amanda Bayless, Goncalo Gouveia, Robert Powers, Valerie Copie, John Cort, Hamid R. Eghbalnia, Wimal Pathmasiri, David S Wishart, Erik Andersson, Robert Brua, Leo Cheng, Chaevien Clendinen, Darcy Cochran, Alexandra Crook, Michah Jeppesen, Amith Maroli, Matthew Merritt, Heidi Roth, Isin Sakallioglu, Saurav Sarma, Lloyd Sumner, Panteleimon Takis, Mario Uchimiya
A literature survey was conducted to identify current practices used by NMR metabolomics investigators. A total of 463 papers from 2020 and 80 papers from 2010 were selected from PubMed. The papers were manually analyzed by a team of investigators to

Untargeted metabolomics analyses and contaminant chemistry of Dreissenid mussels at the Maumee River Area of Concern in the Great Lakes

November 22, 2023
Author(s)
Tracey Schock, Daniel Bearden, Fabio Casu, Michael Edwards, Annie Jacob, Edward Johnson, Amanda Bayless, Elena Legrand
Bivalves stand out as an ideal ecological indicator and have been the basis of NOAA's Mussel Watch Program to monitor environmental health. In this study, we aimed to investigate the health of the Dreissenid mussel in the Maumee River. In addition to the

Metabolomics 2022 Workshop Report: State of QA/QC Best Practices in LC-MS-Based Untargeted Metabolomics, Informed Through mQACC Community Engagement Initiatives

November 8, 2023
Author(s)
Tracey Schock, Warwick Dunn, Julia Kuligowski, Jonathan Mosley, Candice Ulmer Holland, Dajana Vuckovic
Introduction: The Metabolomics Quality Assurance and Quality Control Consortium (mQACC) organized a workshop during the Metabolomics 2022 conference. Objectives: The goal of the workshop was to disseminate recent findings from mQACC community-engagement

Multi-omics characterization of NIST seafood reference materials and alternative matrix preparations

September 18, 2023
Author(s)
Debra Ellisor, Amanda Bayless, Clay Davis, Tracey Schock, Benjamin Trey Knott, John Seghers, Hanne Leys, Hakan Emteborg
The National Institute of Standards and Technology (NIST) has prepared four seafood reference materials (RMs) for use in food safety and nutrition studies: wild-caught and aquacultured salmon (RM 8256 and RM 8257) and wild-caught and aquacultured shrimp

Multi'omic Characterization of Human Whole Stool RGTMs

September 8, 2023
Author(s)
Amanda L. Bayless, Sandra M. Da Silva, Clay Davis, Abraham Kuri Cruz, Tracey Schock, Stephanie Servetas, Paulina Piotrowski
The gut microbiome plays a critical role in a vast and disparate set of health and disease states, including cancer and obesity. Human fecal is a complex mixture including microbes, proteins, undigested plant matter and fat content according to the diet

NMR and Metabolomics -A Roadmap for the Future

July 23, 2022
Author(s)
Tracey Schock, David Wishart, Leo Cheng, Valerie Copie, Arthur Edison, Hamid Eghbalnia, Jeffrey Hoch, Goncalo Gouveia, Wimal Pathmasiri, Robert Powers, Llyod Sumner, Mario Uchimiya
Metabolomics investigates global metabolic alterations associated with chemical, biological, physiological, or pathological processes. These metabolic changes are measured with various analytical platforms. While liquid chromatography-mass spectrometry (LC

Reference Materials for MS-based Untargeted Metabolomics and Lipidomics: A Review by the Metabolomics Quality Assurance and Quality Control Consortium (mQACC)

April 9, 2022
Author(s)
Katrice Lippa, William Davis, Christina Jones, Tracey Schock, Juan Aristizabal-Henao, Richard Beger, John Bowden, Corey Broeckling, Chris Beecher, Warwick Dunn, Roberto Flores, Goncalo Gouveia, Thomas Hartung, Matthew Lewis, Ioanna Ntai, Andrew Percy, Dan Raftery, Jinchun Sun, Georgios Theodoridis, Fariba Tayyari, Federico Torta, Candice Ulmer, Baljit Ubhi
Introduction The metabolomics quality assurance and quality control consortium (mQACC) is enabling the identification, development, prioritization and promotion of suitable reference materials (RMs) to be used in quality assurance (QA) and quality control

Understanding molt control switches: Transcriptomic and expression analysis of the genes involved in ecdysteroidogenesis and cholesterol uptake pathways in the Y-organ of the blue crab, Callinectes sapidus

September 3, 2021
Author(s)
Tracey Schock, Elena Legrand, J. Sook Chung, Tsvetan Bachvaroff
The crustacean molting process is regulated by an interplay of hormones produced by the eyestalk ganglia and Y-organs (YO). Molt-inhibiting hormone and crustacean hyperglycemic hormone released by the sinus gland of the eyestalk ganglia (EG) inhibit the

Evaluation of Graded Levels of Soy Oil as a Fish Oil Replacement in High Soy Protein Feeds for Juvenile Red Drum, Sciaenops ocellatus

June 30, 2020
Author(s)
Tracey B. Schock, Aaron Watson, Michael P. Napolitano, John A. Bowden, Jason Frost, Justin Yost, Michael R. Denson
A 9-week feeding trial was conducted with juvenile red drum, Sciaenops ocellatus, to evaluate the use of soy oil as a fish oil replacement. Three primary protein sources (fishmeal - FM, soybean meal - SBM, and soy protein concentrate - SPC) were utilized

Examining Mercury Transfer in the American Alligator

December 6, 2019
Author(s)
Stephen E. Long, Tracey B. Schock, Nilsen Frances
American alligators are exposed to mercury (Hg) throughout their natural range and may maternally transfer Hg into their eggs. Wildlife species are highly sensitive to Hg toxicity during embryonic development and neonatal life, and information on Hg

Remote blubber sampling paired with liquid chromatography tandem mass spectrometry for steroidal endocrinology in free-ranging bottlenose dolphins (Tursiops truncatus)

June 11, 2019
Author(s)
Ashley S. Boggs-Russell, Jared M. Ragland, Eric Zolman, Tracey B. Schock, Jeanine S. Morey, Thomas M. Galligan, Greta Dalle Luche, Brian C. Balmer, Randall S. Wells, John R. Kucklick, Lori Schwacke
Liquid chromatography tandem mass spectrometry allows for the measurement of steroid hormone suites in the blubber of marine mammals. By combining this technology with minimally invasive techniques such as remote biopsy, endocrine profiles can be assessed

Examining American Alligators as Sentinels of Toxic Trace Element Exposure in Human Populations

April 15, 2019
Author(s)
Frances Nilsen, Thomas Rainwater, Stephen E. Long, Tracey Johnston, Philip Wilkinson, Arnold Brunell, Brittany Kassim, John A. Bowden
Mercury (Hg) is a ubiquitous toxic element eliciting a myriad of health problems including Minamata disease. Exposure to methylmercury, the most toxic bioaccumulative form of Hg, occurs through aquatic dietary sources. Many nations have consumption

Examining Heat Treatment for Stabilization of the Lipidome

February 16, 2018
Author(s)
John Bowden, Candice Z. Ulmer, Christina Jones, Tracey Johnston, Jeremy P. Koelmel, Timothy J. Garrett, Richard A. Yost
Aim: To confidently determine lipid-based biomarkers, it is important to minimize variation introduced during preanalytical steps. We evaluated reducing variation associated with lipid measurements in invertebrate sentinel species using a state-of-the-art

Trichothiazole A, a dichlorinated polyketide featuring an embedded thiazole isolated from Trichodesmium thiebautii blooms

September 18, 2017
Author(s)
Tracey B. Schock, Peter D. Moeller, Rick Belisle, Christopher W. Via, Tracy A. Villareal, Kevin Beauchesne, Matthew J. Bertin, Paul Zimba
Mass spectrometry-guided isolation of the lipophilic extract of Trichodesmium thiebautii bloom material led to the isolation and structure characterization of a new thiazole-containing di-chlorinated polyketide (1). The structure of 1 was deduced using 1D

Seasonal variation of total mercury burden in the American alligator (Alligator mississippiensis) at Merritt Island National Wildlife Refuge (MINWR), Florida

July 8, 2017
Author(s)
Frances Nilsen, Jonathan E. Dorsey, Stephen E. Long, Tracey B. Schock, John A. Bowden, Russell H. Lowers, Louis J. Guillette Jr.
Seasonal variation of mercury (Hg) is not well studied in free-ranging wildlife. Atmospheric deposition patterns of Hg have been studied in detail and have been modeled for both global and specific locations with great accuracy and correlates to