Skip to main content

NOTICE: Due to a lapse in annual appropriations, most of this website is not being updated. Learn more.

Form submissions will still be accepted but will not receive responses at this time. Sections of this site for programs using non-appropriated funds (such as NVLAP) or those that are excepted from the shutdown (such as CHIPS and NVD) will continue to be updated.

U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

This page is no longer being updated and the information may be out of date.

Context: Toxicity and Hazard



Evaluation of Halon Alternatives.. Robin, M. L.; 1991

Air Force Approach to Toxicology of Halon Replacements.. McDougal, J. N.; Dodd, D. E.; 1992

Human Health and Environmental Toxicity Issues for Evaluation of Halon Replacements.. Rubenstein, R.; 1992

Implications of Using Halon and CFC Substitutes on Occupational Safety and Health Standards.. Perry, W.; Kent, M.; 1992

Metabolism and Pharmacokinetics of Halon 1211 and Its Potential Replacements HCFC-123 and Perfluorohexane.. Brashear, W. T.; Vinegar, A.; 1992

Toxicity Testing of Alternatives: An Industry Perspective.. Derelanko, M. J.; 1992

Development of Perfluoroalkanes as Clean Extinguishing Agents: System and Fire Test Protocols.. Pignato, J. A., Jr.; Rivers, P. E.; Pike, M. T.; 1993

Final Firefighter Exposure Results: A Comparison of Halon 1211, HCFC 123 and PFH.. Floden, J. R.; Scheil, G.; Klamm, S.; 1993

Hazard Assessment of Thermal Decomposition Products of Halon Alternatives.. Hanauska, C.; Forssell, E. W.; DiNenno, P. J.; 1993

Overview of Toxicity/Effectiveness Issues.. Laursen, T.; 1993

Recommending Exposure Limits for Halon Replacements.. McDougal, J. N.; Dodd, D. E.; Skaggs, S. R.; 1993

Short Duration High-Level Exposure to Halon Substitutes: Potential Cardiovascular Effects.. Rubenstein, R.; Bellin, J. S.; 1993

Structure-Activity Relationship of 2- and 3-Carbon Halogenated Halocarbons.. Skaggs, S. R.; 1993

Fluoroiodocarbons as Halon 1211/1301 Replacements: An Overview.. Kibert, C.; 1994

Perfluorohexane Clean Extinguishing Agent for Streaming and Local Application systems.. Pignato, J. A., Jr.; Ruffing, J. F.; 1994

Regulation of Halon and Halon Substitutes. Keynote Address.. Metchis, K.; 1994

Toxicological Assessment of a Fire Suppressant and Potential Substitute for Ozone Depleting Sustances.. Smith, E. A.; Kimmel, E. C.; Bowen, L. E.; Reboulet, J. E.; Carpenter, R. L.; 1994

90-Day Inhalation Toxicity Study of CF3I in Fischer 344 Rats.. Vinegar, A.; Kinkead, E. R.; Leahy, H. F.; English, J. H.; Jepson, G. W.; 1995

Assessment of Toxicity After Exposure to a Pyrotechnically-Generated Aerosol.. Smith, E. A.; Kimmel, E. C.; English, J. H.; Carpenter, R. L.; 1995

Halon Alternatives Health Effects Assessment.. Rubenstein, R.; 1995

Physical and Chemical Characteristics of SFE Fire Suppressant Atmospheres: Comparison of Small With Large Scale Laboratory Atmospheres.. Kimmel, E. C.; Smith, E. A.; Reboulet, J. E.; Black, B. H.; Sheinson, R. S.; Carpenter, R. L.; 1995

Toxicological Evaluation of a Halon Replacement.. Chengelis, C. P.; Nemec, M. D.; Nass, D. J.; Walter, G. J.; 1995

U.S. Environmental Protection Agency: Regulatory Update.. Metchis, K.; 1995

Ab Initio Calculations and Kinetic Modeling of Halon and Halon Replacements.. Paige, H. L.; Berry, R. J.; Schwartz, M.; Marshall, P.; Burgess, D. R. F., Jr.; Nyden, M. R.; 1996

Determinants of SFE Toxicity: Interaction of Atmospheric, Dynamic, and Physiological Responses.. Carpenter, R. L.; Kimmel, E. C.; Smith, E. A.; 1996

Laboratory Optimization and Medium-Scale Screening of Iodide Salts and Water Mixtures.. Moore, T. A.; Weitz, C. A.; McCormick, S.; Caluson, M. S.; 1996

Physicochemical Properties of SFE Fire Suppressant Atmospheres in Toxicity vs. Fire Extinguishment Tests: Implications for Aerosol Deposition and Toxicity.. Kimmel, E. C.; Smith, E. A.; Reboulet, J. E.; Carpenter, R. L.; 1996

Pulmonary Edemagenesis in F-344 Rats Exposed to SFE (Fromulation A) Atmospheres.. Kimmel, E. C.; Smith, E. A.; Prues, S.; Zepp, K.; English, J. H.; Carpenter, R. L.; 1996

Toxic Gas Measurement in Inhibited Flames Using Tunable Diode Laser Spectroscopy.. McNesby, K. L.; Daniel, R. G.; Modiano, S. H.; Miziolek, A. W.; 1996

Toxicological Evaluation of Exposure to Two Formulation of a Pyrotechnically-Generated Aerosol: Range Finding and Multiple Dose.. Smith, E. A.; Kimmel, E. C.; Reboulet, J. E.; Prues, S.; Zepp, K.; Bulger, S.; Cassell, J. L.; Carpenter, R. L.; 1996

Concepts in the Inhalation Toxicity of Fire Suppressants: Pneumotoxicity.. Kimmel, E. C.; Carpenter, R. L.; 1997

Determination of Risk Factors for Acute Exposure to Powdered Aerosols.. Rusch, G. M.; 1997

Development of Quantitative Structure-Property Relationships for Screenings of Tropodegradable Halocarbons.. Grzyll, L. R.; Back, D. D.; Vitali, J. A.; Linscheer, G.; 1997

PBPK Modeling of CF3I Releases From F15 Engine Nacelles.. Vinegar, A.; Jepson, G. W.; 1997

Cardiac Sensitization: Methods Development and Understanding the Hazard and Potential Risk.. Brock, W. J.; 1998

Examining the Risks of Carbon Dioxide as a Fire Suppressant.. Skaggs, S. R.; 1998

Next-Generation Fire Suppression Technology Program.. Gann, R. G.; 1998

Pharmacokinetic Modeling for Determining Egress From Exposure to Halon Replacement Chemicals.. Vinegar, A.; Jepson, G. W.; 1998

Review of the Inhalation Toxicity of Hydrogen Fluroide.. Delly, D. P.; 1998

Epinephrine Challenge for Cardiac Sensitization Testing VS. Endogenous Epinephrine: A Perspective.. Vinegar, A.; Jepson, G. W.; 1999

Hydrogen Fluoride: How Toxic Is Toxic? (A Hazard and Risk Analysis).. Brock, W. J.; 1999

Potential CF3I Depolyment: An Airframe Perspective.. Harper, G.; Kay, M. C.; 1999

Setting the Occupational Exposure Limit for CF3I.. Skaggs, S. R.; Rubenstein, R.; 1999

Toxicity Data Comparison of CF3I With Currently Used Fire-Extinguishing Agents and Refrigerants of Interest to the Military.. Dodd, D. E.; Vinegar, A.; 1999

Toxicity Review for Iodotrifluoromethane (CF3I).. McCain, W. C.; Macko, J. C.; 1999

Comparative Testing of Halon 1301 Substitutes Using a Method for Assessing Toxic Hazard.. Kopylov, N. P.; Ilitchkine, V. A.; Potanine, B. V.; Belevtsev, J. G.; 2000

Tropodegradable Bromocarbon Extinguishants: Progress Overview.. Mather, J. D.; Tapscott, R. E.; 2000

Update on NFPA 2001 and ISO/fDIS 14520 Standards.. Robin, M. L.; 2000

Effect of Fire Size on Suppression Characteristics of Halon Replacement Total-Flooding Systems.. Kashiwagi, H.; Oshikawa, S.; Yui, J.; Saso, Y.; 2001

Toxic Hazard Associated With Fire Engineering Aerosols: The Current State of the Art and a Method for Assessment.. Kopylov, N. P.; Ilitchkine, V. A.; Potanine, B. V.; Novikov, I. A.; 2001

Development and Testing of Goodrich 244 Fire Suppressant.. Olander, D. E.; 2002

Toxicity Screening of Halogenated Aliphatics Using a Novel In Vitro Volatile Chemical Exposure System.. Geiss, K. T.; Frazier, J. M.; Dodd, D. E.; 2002

Tropodegradable Bromocarbon Extinguishants: Compound Selection and Testing Issues.. Mather, J. D.; Tapscott, R. E.; 2002

Study of Effect of Aerosol and Vapor of Organophosphorus Fire Suppressants on Diffusion Heptane and Premixed C3H8/Air Flames.. Korobeinichev, O. P.; Shmakov, A. G.; Shvartsberg, V. M.; Knyazkov, D. A.; Makarov, V. I.; Koutsenogii, K. P.; Samsonov, Y. N.; Nifantev, E. E.; Kudryavtsev, I. Y.; Goryunov, E. I.; Nikolin, V. P.; Kaledin, V. I.; 2003

Suitability of CF3I to Replace Halon 1301 as the Inerting Agent in Wing Fuel Tanks on the F-16 Aircraft.. Gann, R. G.; 2003

Tropodegradable and Other Environmentally Acceptable Flame Extinguishants NAGP Elements: 4D/14/1 and 4B/6/23.. Mather, J. D.; Tapscott, R. E.; 2003

Environmentally Acceptable Flame Extinguishants NGP Element: 4D/6/23.. Mather, J. D.; Tapscott, R. E.; 2004

Next Generation Fire Suppression Technology Program: FY2004 Progress.. Gann, R. G.; 2004

Study of Effectiveness of Flame Suppression by Organophosphorus Compounds in Laboratory and Scaled-Up Tests.. Korobeinichev, O. P.; Shmakov, A. G.; Chernov, A. A.; Shvartsberg, V. M.; Rybitskaya, I. V.; Makarov, V. I.; Nifantev, E. E.; Kudryavtsev, I. Y.; Goryunov, E. I.; 2004

Environmentally Acceptable Flame Extinguishants.. Mather, J. D.; Tapscott, R. E.; 2005

Evaluation of Calculation Methodologies for the Safe Use of Clean Agents Onboard Aircraft.. Colton, B. A.; Nay, A.; 2005

Research and Development Program of the German Armed Forces Scientific Institute for Protection Technologies in the Field of Fire Protection and Halon Replacement.. Schilling, H.; Pauli, R.; Kummerlen, F. R.; Grabski, R.; 2005

Methods of Quantifying and Mitigating Aerosol Fire and Explosion Hazards Associated With Low Vapor Pressure Liquids.. Willauer, H. D.; Ananth, R.; Hoover, J. B.; Mushrush, G. W.; Williams, F. W.; 2006

Screening Tests for Alternative Suppressants for In-Flight Aircraft Fires.. Gann, R. G.; 2006

Created December 6, 2011, Updated September 23, 2025
Was this page helpful?