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EVENTS

Genome Editing Consortium Workshop

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Genome editing technologies

The purpose of this workshop is to share and obtain feedback on current and future activities of the NIST Genome Editing Consortium. Discussion topics will include control materials/assay qualification for DNA detection, genome editing data/metadata norms, and newly launched sub-groups focused on controls for and qualification of off-target assays, and quality of genome editing components.

 

Thursday, June 12th will be our public NIST Genome Editing Workshop. Friday, June 13th will be a closed members-only meeting.

 

Please use the registration button to the right to register for the event. Registration deadline is June 6th, 2025.

All times in Eastern Standard Time

9:00 am – 9:15 am 

Welcome & Opening Remarks 

Workshop Overview 

9:15 - 10:00 am 

Update from Federal Partners with Related Efforts  

FDA-CVM Regulatory Bioinformatics Analysis of Intentional Genomic Alterations (IGAs) in Animals
     Alexis Norris, Bioinformatician
     U.S. Food and Drug Administration, Center for Veterinary Medicine (FDA CVM)


Update on the  NIH Common Fund Somatic Cell Genome Editing (SCGE) Consortium 
     Philip. J. Brooks, Co-Coordinator, SCGE program, Deputy Director, Division of Rare Diseases Research Innovation , NCATS, NIH 
     Division of Rare Diseases Research Innovation , National Center for Advancing Translational Sciences, NIH


How ARPA-H is leaning into NIST GE Consortium to support EMBODY performers 
     Daria Fedyukina, Program Manager
     The Advanced Research Projects Agency for Health (ARPA-H) 
 

10:00 – 10:40 am 

Current NIST Genome Editing Consortium Activities
Update and Discussion of Next Steps  

                 Victor J. Weigman, VP, Computational Biology & Analytics
                 Bioskryb Genomics, Inc.

                 Ayah Shevchenko, Bioinformaticist
                 NIST Genome Editing Program

 

10:40 am - 11:00 am

BREAK

11:00 am – 12:00 pm 

Current NIST Genome Editing Consortium Activities 
Update and Discussion of Next Steps  
(continued)

  • WG1-SUBGROUP: QUALITY OF GENOME EDITING COMPONENTS
    Subgroup Objective: Identify sources of variability and develop consensus approaches to qualifying off-target assays (including potential interlaboratory studies or control materials)

                   Samantha Maragh, Leader
                   NIST Genome Editing Program

 

  • WG1- SUBGROUP: QUALIFICATION OF OFF-TARGET ASSAYS
    Subgroup Objective: Identify concepts/information, approaches/assays, and potential controls for assessing quality of genome editing components

                   Puzhou Wang, Director, Research & Data
                   Synthego Corporation

                   Gavin Kurgan, Bioinformatics Applications and Market Development Manager
                   Integrated DNA Technologies (IDT), Inc.

12:00 – 1:00 pm 

BREAK

1:00 - 1:45 pm

Current NIST Genome Editing Consortium Activities
Update and Discussion of Next Steps
(continued)

                   Sierra Miller, Bioinformaticist
                   NIST Genome Editing Program

                   Cole Lyman, Chief Executive Officer
                   McKay Bowcut, Software Developer
                   Trevor Martin, Software Developer
                   Edilytics, Inc. 

 

  • WG3 Lexicon:  ISO 5058 GENOME EDITING PT 1 VOCABULARY; ADDITIONAL TERMS TO CONSIDER 

                   Samantha Maragh, Leader
                   NIST Genome Editing Program

1:45 - 2:30 pm

Breakout Topics

  • OFF-TARGET GENOME EDITING: ANALYSIS, INTERPRETATION, & METADATA

                   Samantha Maragh, Leader
                   Patty Kiesler, Biologist 
                   Sierra Miller, Bioinformaticist 
                   Ayah Shevchenko, Bioinformaticist
                   NIST Genome Editing Program

                  Speaker TBD                   
                  Integrated DNA Technologies (IDT), Inc.

2:30 - 2:45 pm

BREAK

2:45 - 3:45 pm  

Breakout Topics 
(continued)

  • MEASUREMENT CHALLENGES AND CONSIDERATIONS FOR EPIGENETIC EDITORS

                 Keith Szulwach, Associate Director, Genome Sciences
                 Ofer Yizhar-Barnea, Senior Scientist, Genome Sciences
                 Scribe Therapeutics Inc.

  • AI IN GENOME EDITING

                Grace Tiao, CEO
                Tim Poterba, CTO
                E9 Genomics

                CRISPR Genome Editing: Guide RNA Design using DNA Foundational Models
                Yaniv Shmueli, PhD, CTO & Co-founder
                 Cassidy Bio
 

3:45 - 4:00 pm

BREAK

4:00 – 5:00 pm  

Technology Talks 
(10 mins each)

  • Precision Genotyping Tools for Gene Editing Analysis and Characterization 
    Iván Hernández, CSO
    Countagen AB
     
  • Precision Genome Editing Analysis with CRISPResso 
    Cole Lyman, Chief Executive Officer
    Edilytics, Inc.
     
  • Transposase-Based Tools for Genome Editing QC Workflows 
    Joseph Mellor, PhD, Co-Founder and Chief Scientific Officer
    seqWell, Inc.
     
  • Deep Reasoning with Biological Data: from Gene Editing Target Identification to Off-Target Prioritization and Interpretation 
    Grace Tiao, CEO 
    Tim Poterba, CTO
    E9 Genomics
     

5:00 – 5:15 pm  

Re-Cap of Workshop & Adjourn  

Bioscience, Bioeconomy, Bioinformatics, Biometrology, Genome engineering, Genome editing, Health, Biopharmaceuticals, Cell and gene therapy, Precision medicine and Regenerative medicine and advanced therapy
Created November 6, 2024, Updated June 11, 2025
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