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Biomolecular Structure and Function Group

The Biomolecular Structure and Function Group advances new measurement methods and modeling tools for structural analysis of biomolecules and biomolecular complexes.

In collaboration with U.S. industry, government agencies, and scientific institutions, the Biomolecular Structure and Function Group develops precision measurement and modeling tools and standards to support determination of biomolecular structure, dynamics, energetics and function.  The group also advances innovative approaches for engineering biological systems to support applications in biotechnology and bioscience research.  

Our group is located at the Institute for Bioscience and Biotechnology Research (IBBR), a joint institute of the University of Maryland and NIST.  For information on group activities please visit IBBR

News and Updates

Projects and Programs

Biomanufacturing Initiative

Ongoing
Protein drugs are the top selling pharmaceuticals worldwide, a hundred billion dollar industry, but also the fastest growing category of health care costs. The

Publications

Design and characterization of a protein fold switching network

Author(s)
David Travis Gallagher, Biao Ruan, Yanan He, Yingwei Chen, Eun Jung Choi, Yihong Chen, Dana Motabar, Tsega Solomon, Richard Simmerman, Thomas Kauffman, John Orban, Philip Bryan
Protein sequences encoding three common small folds (3-alpha, beta-grasp, and alpha/beta plait) were connected in a network of mutational pathways that

Awards

Contacts

Group Leader