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Gaithersburg

FCSC Impacts

The NIST Flow Cytometry Standards Consortium promotes: Shared measurement assurance tools and standards for flow cytometry measurement...
Schematic of a three stage process. Stage 1 flow cytometry data and clinical data and/or information are collected as inputs. Stage 2 inputs are used to build an AI/ML model that can be predictive, clustering, generative or large language. Stage 3 applies the model to predict clinical outcomes, identify and/or correlate biomarkers, and cluster by cell type or function. Rounds of generating hypotheses and updating data or models iteratively feed back into stages 1 and 2 to generate new results.

FCSC Working Group 5

Artificial Intelligence and Machine Learning (AI/ML) Approaches Working Group 5 (WG5), once launched, will use high-quality reference...
A figure with two panels. Left panel shows the activities of WG4-ILS1 physical titer, WG4-ILS2 infectious titer, and WG4-ILS3 purity, as funneling into the result of measurement assurance for gene delivery systems and potential generation of standard methods, reference materials or reference data. Right panel shows the activities of WG4-ILS1 that will be distributed to labs through sharing contributed materials for measurements of genome titer, capsid titer, particle concentration, and other methods.

FCSC Working Group 4

Gene Delivery Systems Working Group 4 (WG4) efforts are focused on identifying and minimizing the sources of variability in assays of gene...
A figure in three panels. Left panel, beginning in upper left, shows the information, descriptors and types or filetypes for WG1-ILS1 calibrations as a subset of, below, additional information for samples and controls in WG2-ILS1. Data were collected by all 17 orgs as the input for WG3 ILS1 tasks. Middle panel shows input data in a structured repository moving through consensus analysis and resulting in post-processed reference data and analysis reports. Right panel shows outputs and dissemination.

FCSC Working Group 3

Data Repository and Centralized Data Analysis Working Group 3 (WG3) organizes, analyzes and disseminates the data generated by Consortium...

FCSC Working Group 2

Flow Cytometry Assay Standardization Working Group 2 (WG2) designs and conducts interlaboratory studies for the development of standards...
Schematic demonstrating, in the upper half, how comparing the fluorescence spectra of reference fluorophore solutions to the fluorescence spectra of calibration beads allows, in the lower half, calibrations made using different calibration beads to become comparable measurements through the equivalent number of reference fluorophores (ERF) value.

FCSC Working Group 1

ERF-Based Instrument Calibration and Standardization Working Group 1 (WG1) is developing standards including reference materials, reference...

FCSC Events

The Consortium holds monthly members only meetings to advance the goals of the Consortium. Current Consortium members can access past...

FCSC Membership

Become a Member of the NIST Flow Cytometry Standards Consortium Complete the Letter of Interest (electronic form). Participants will enact a...
FCMN 2026: March 16-19, 2026

FCMN

The International Conference on Frontiers of Characterization and Metrology for Nanoelectronics (FCMN) brings together scientists and...

Material Jetting

Material jetting forms solid structures from liquid material. Similar to traditional inkjet printing, material jetting builds objects by...

Binder Jetting

Binder jetting prints three-dimensional structures by fusing powdered material together with a binder. The technique can produce colorful...

Vat Photopolymerization

Vat photopolymerization forms structures by curing liquid photopolymer resin with ultraviolet light. The structure is submerged, raised, and...

Material Extrusion

Material extrusion can produce three-dimensional structures by building up material layer-by-layer. This technique is commonly used by...

Directed Energy Deposition

Directed energy deposition (DED) builds up material layer-by-layer. A nozzle deposits and melts material onto a target with a directed beam...

Powder Bed Fusion

Powder bed fusion can produce functional parts by melting and fusing layers of powdered material (e.g. metal) with either a high-power laser...