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Search Publications by: David P. Hoogerheide (Fed)

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Displaying 26 - 33 of 33

Optimization of Reflectometry Experiments using Information Theory

February 1, 2019
Author(s)
Bradley W. Treece, Paul A. Kienzle, David Hoogerheide, Charles Majkrzak, Mathias Loesche, Frank Heinrich
A method based on Bayesian statistics and information theory is developed to analyze the information gain Δ}H of surface-sensitive reflectometry experiments. After presenting the underlying mathematical framework and its implementation, the method is

Real-Time Nanopore-Based Recognition of Protein Translocation Success

February 27, 2018
Author(s)
David Paul Hoogerheide, Philip A. Gurnev, Tatiana K. Rostovtseva, Sergey M. Bezrukov
A growing number of new technologies are supported by a single- or multi-nanopore architecture for capture, sensing, and delivery of polymeric biomolecules. 1-6 Nanopore-based single-molecule DNA sequencing, in which engineered nanopores 7 are augmented

Structural Features and Lipid Binding Domain of Tubulin on Biomimetic Mitochondrial Membranes

April 18, 2017
Author(s)
David Paul Hoogerheide, Sergei Y. Noskov, Daniel Jacobs, Lucie Bergdoll, Vitalii Ivanovich Silin, David L. Worcester, Jeff Abramson, Hirsh Nanda, Tatiana K. Rostovtseva, Sergey M. Bezrukov
Amphitropic proteins, the subfamily of peripheral membrane proteins that interact directly with lipid bilayers, comprises members whose function depends on their localization either in the cytosol or at the cellular membranes. Despite the well-established

Conductance Hysteresis in the Voltage-Dependent Anion Channel

September 1, 2015
Author(s)
Shay M. Rappaport, Oscar Teijido, David Hoogerheide, Tatiana K. Rostovtseva, Alexander M. Berezhkovskii, Sergey M. Bezrukov
In contrast to the voltage gating of ion-selective channels of electrophysiology, the mechanisms of voltage sensitivity of ¿large¿ beta-barrel channels remain obscure, even at the conceptual level. Here we study hysteresis in the conductance response of
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