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Search Publications by: John Pettibone (Fed)

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Displaying 1 - 25 of 30

Rapid chemical screening of microplastics and nanoplastics by thermal desorption and pyrolysis mass spectrometry with unsupervised fuzzy clustering

August 11, 2023
Author(s)
Thomas P. Forbes, John Pettibone, Eric S. Windsor, Joseph M. Conny, Robert A. Fletcher
The transport and chemical identification of microplastics and nanoplastics (MNPs) are critical to the concerns over plastic accumulation in the environment. Chemically and physically transient MNP species present unique challenges for isolation and

Improved Accuracy for Calibrated Mass Distribution Measurements of Bimetallic Nanoparticles

May 23, 2022
Author(s)
Kaleb Duelge, George Mulholland, Antonio Montoro Bustos, Michael Zachariah, Michael Zachariah, John Pettibone
Implementation of hybrid nanoparticles (HNPs), consisting of two different metal components, into applied systems has been hindered by an incomplete understanding of structural and chemical properties responsible for their enhanced, yet inconsistent

Parallel multi-parameter study of PEI-functionalized gold nanoparticle synthesis for bio- medical applications: Part 2. Elucidating the role of surface chemistry and polymer structure on performance

November 10, 2020
Author(s)
Tae Joon Cho, Justin M. Gorham, John M. Pettibone, Jingyu Liu, Jiaojie Tan, Vincent A. Hackley
Despite the breadth and quality of published work in this area, it remains unclear how the specific properties of polyethyleneimine (PEI) and the methods utilized to conjugate it to gold nanoparticles (AuNPs) impact the final product morphology and

Parallel multi-parameter study of PEI-functionalized gold nanoparticle synthesis for bio-medical applications: Part 1. A critical assessment of methodology, properties and stability

August 20, 2019
Author(s)
Tae Joon Cho, Justin M. Gorham, John M. Pettibone, Jingyu Liu, Jiaojie Tan, Vincent A. Hackley
Cationic polyethyleneimine (PEI) conjugated gold nanoparticles (AuNPs) that are chemically and physically stable under physiological conditions are an ideal candidate for certain bio-medical applications, in particular DNA transfection. However, the

Discriminated properties of PEI functionalized gold nanoparticles (Au-PEIs) predetermined by synthetic routes of ligand exchange and reduction processes: Paths and Fates

June 17, 2019
Author(s)
Tae Joon Cho, John M. Pettibone, Vincent A. Hackley
Polyethyleneimine (PEI) functionalized AuNPs (Au-PEIs) are have potent as positively charged gold nanoparticles (AuNPs) for nano-medicinal applications, due to their cationic surfaces that promote cellular uptake and gene transfection. 1-6 1-6 1-61-6 Au

Transformation of Engineered Nanomaterials through the Prism of Silver Sulfidation

January 1, 2019
Author(s)
Fan Zhang, Andrew J. Allen, Aaron C. Johnston-Peck, Jingyu Liu, John M. Pettibone
Structure transformation of engineered nanomaterials (ENMs) often dictates their efficacy, safety, and environmental impact. To address the existing significant knowledge gap regarding the fundamental kinetic rate and extent of ENMs transformation in

Surface Modification of Cisplatin-Complexed Gold Nanoparticles and Its Influence on Colloidal Stability, Drug Loading, and Drug Release

November 10, 2017
Author(s)
Jiaojie Tan, Tae Joon Cho, De-Hao Tsai, Jingyu Liu, John M. Pettibone, Rian You, Michael R. Zachariah, Vincent A. Hackley
Cisplatin-complexed gold nanoparticles (PtII-AuNP) provide a promising strategy for chemo- radiation based anticancer drugs. Effective design of such platforms necessitates reliable assessment of surface engineering on a quantitative basis, and its

Research highlights: Probing adsorbed organic coatings on nanoparticle surfaces

October 1, 2015
Author(s)
Stacey M. Louie, John M. Pettibone
Organic coatings adsorbed at a nanoparticle surface, together with the system properties, change the physicochemical properties of the nanoparticle, thereby possibly modifying its behavior and interactions with its surroundings. A detailed understanding of

Accurate determination of the size distribution for polydisperse, cationic metallic nanomaterials by asymmetric-flow field flow fractionation

November 13, 2014
Author(s)
Julien C. Gigault, Thao M. Nguyen, John M. Pettibone, Vincent A. Hackley
In this work we have developed and validated a methodology for determining the size distribution in polydisperse cationic nanoparticle (NP) samples using asymmetric-flow field flow fractionation (A4F), where known compositional influence of previously used

Temperature-Programmed Electrospray-Differential Mobility Analysis for Characterization of Ligated Nanoparticles in Complex Media

August 12, 2013
Author(s)
De-Hao D. Tsai, Frank W. DelRio, John M. Pettibone, Pin A. Lin, Jiaojie Tan, Michael R. Zachariah, Vincent A. Hackley
In this study, an electrospray-differential mobility analyzer (ES-DMA) was operated with an aerosol flow-mode, temperature-programmed approach to enhance its ability to characterize the particle size distributions (PSDs) of nanoscale particles (NPs) in the

Surface mediated assembly of small, metastable gold nanoclusters

May 27, 2013
Author(s)
John M. Pettibone, William A. Osborn, Konrad Rykaczewski, Albert A. Talin, John E. Bonevich, Jeffrey W. Hudgens
The unique properties of metallic nanoclusters are attractive for numerous commercial and industrial applications but are generally less stable than nanocrystals. Thus, developing methodologies for stabilizing nanoclusters and retaining their enhanced