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Displaying 18826 - 18850 of 74256

2D 1HN, 15N Correlated NMR Methods at Natural Abundance for Obtaining Structural Maps and Statistical Comparability of Monoclonal Antibodies

March 1, 2015
Author(s)
Luke Arbogast, Robert G. Brinson, Catherine A. Mouchahoir, James T. Hoopes, John Marino
Purpose High-resolution nuclear magnetic resonance spectroscopy (NMR) provides a robust approach for producing unique spectral signatures of protein higher order structure at atomic resolution. Such signatures can be used as a tool to establish consistency

Adiabatic optimization without local minima

March 1, 2015
Author(s)
Stephen P. Jordan, Michael Jarret
Several previous works have investigated the circumstances under which quantum adiabatic optimization algorithms can tunnel out of local energy minima that trap simulated annealing or other classical local search algorithms. Here we investigate the even

Coexistence of Superconductivity and Antiferromagnetism in (Li 0.8 Fe 0.2 ) OHFeSe

March 1, 2015
Author(s)
X. F. Lu, N. Z. Wang, Hui Wu, Y. P. Wu, D. Zhao, X. Z. Zeng, X. G. Luo, T. Wu, W. Bao, G. H. Zhang, F. Q. Huang, Qingzhen Huang, X. H. Chen
FeSe-derived superconductors show some unique behaviors relative to iron-pnictide superconductors, which are very helpful to understand the mechanism of superconductivity in high-T c iron-based superconductors. The low-energy electronic structure of the

Considerations for Design and In-Situ Calibration of High Accuracy Length Artifacts for Field Testing of Laser Trackers

March 1, 2015
Author(s)
Aaron Hudlemeyer, Daniel S. Sawyer, Christopher J. Blackburn, Vincent Lee, Mark Meuret, Craig M. Shakarji
Interim testing of laser trackers can be problematic due to the lack of high precision, long length artifacts that maintain their calibrated lengths during measurement. Gravitational loading, fixturing forces, and changes in the atmospheric conditions can

Fuzz Testing for Software Assurance

March 1, 2015
Author(s)
Vadim Okun, Elizabeth N. Fong
Fuzz Testing, or fuzzing, is a software testing technique that involves providing invalid, unexpected, or random test inputs to the software system under test. The system is then monitored for crashes and other undesirable behavior. Fuzz testing can be

Investigation of Surrogate Smoldering Ignition Sources for Testing Soft Furnishings

March 1, 2015
Author(s)
Richard G. Gann, Morgan Bruns, Amanda Robbins, Edward Hnetkovsky, Michael Ladas
The introduction of cigarette ignition propensity standards has led to a reduction in the availability of high ignition propensity commercial cigarettes. Since high ignition propensity cigarettes are needed for soft furnishing flammability tests, a

Mapping Monoclonal Antibody Structure by 2D 13C NMR at Natural Abundance

March 1, 2015
Author(s)
Luke Arbogast, Robert G. Brinson, John Marino
Monoclonal antibodies (mAbs) represent an important and rapidly growing class of biotherapeutics. Correct folding of a mAb is critical for drug efficacy, while misfolding can impact safety by eliciting unwanted immune or other off-target responses. Robust

Reference Diffraction Patterns, Microstructure, and Pore Size Distribution for the Copper (II) benzene-1,3,5-tricarboxylate Metal Organic Framework (Cu-BTC) Compounds

March 1, 2015
Author(s)
Winnie K. Wong-Ng, James A. Kaduk, Daniel W. Siderius, Andrew J. Allen, Laura Espinal, Brad Boyerinas, Igor Levin, Matthew Suchomel, Jan Ilavsky, Eric J. Cockayne, Hui Wu
Cu-paddle-wheel-based Cu3(BTC)2 (nicknamed Cu-BTC, where BTC ≡ benzene 1,3,5-tricarboxylate) is a metal organic framework (MOF) compound that adopts a zeolite topology. We have determined the pore size distribution using the Gelb and Gubbins technique, the

Characterizing Task-Based Human-Robot Collaboration Safety in Manufacturing

February 27, 2015
Author(s)
Jeremy A. Marvel, Joseph A. Falco, Ilari Marstio
A new methodology for describing the safety of human-robot collaborations is presented. Taking a task-based perspective, a risk assessment of a collaborative robot system safety can be evaluated offline during the initial design stages. This risk

Competition Between the Inter- and Intra-sublattice Interactions in Yb 2 V 2 O 7

February 27, 2015
Author(s)
Z. L. Dun, J. Ma, H. B. Cao, Yiming Qiu, John R. Copley, T. Hong, M. Matsuda, J. G. Cheng, M. Lee, E. S. Choi, S. Johnston, H. D. Zhou
We studied single crystals of Yb 2V 2O 7 using dc and ac susceptibility measurements, elastic and inelastic neutron scattering measurements, and linear spin wave theory. The experimental data shows a ferromagnetic ordering of V 4+ ions at 70 K, a short
Displaying 18826 - 18850 of 74256
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