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Displaying 626 - 650 of 1284

Quantitative bottom-up proteomics depends on digestion conditions

December 2, 2013
Author(s)
Mark S. Lowenthal, Yuxue Liang, Karen W. Phinney, Stephen E. Stein
Accurate quantification is a fundamental requirement in the fields of proteomics and biomarker discovery, and for clinical diagnostic assays. To demonstrate the extent of quantitative variability in measurable peptide concentrations due to differences

Prototype Phantoms for Characterization of Ultra-Low Field Magnetic Resonance Imaging

November 26, 2013
Author(s)
Michael A. Boss, John A. Mates, Sarah E. Busch, Paul SanGiorgio, Stephen E. Russek, Kai Buckenmaier, Kent D. Irwin, Hsiao-Mei Cho, Gene C. Hilton, John Clarke
Purpose: Prototype phantoms were designed, constructed, and characterized for the purpose of calibrating ultralow field magnetic resonance imaging (ULF MRI) systems. The phantoms were designed to measure spatial resolution and to quantify sensitivity to

Airbrushed Nanofiber Scaffolds Support Bone Marrow Stromal Cell Differentiation

November 1, 2013
Author(s)
Carl G. Simon Jr., Wojtek J. Tutak, Sumona Sarkar, Tanya M. Farooque, Jyotsnendu J. Giri, Dongbo Wang, Sheng Lin-Gibson, Joachim Kohn, Durgadas Bolikal
Nanofiber scaffolds are effective for tissue engineering since they emulate the fibrous nanostructure of native extracellular matrix (ECM). Although electrospinning has been the most common approach for fabricating nanofiber scaffolds, airbrushing

Determining carbapenemase activity with 18O labeling and targeted mass spectrometry

October 16, 2013
Author(s)
Meiyao Wang, Yang Shen, Illarion Turko, Daniel Nelson, Shuwei Li
Carbapenems are broad spectrum antibiotics considered as last resort drugs to treat bacterial infections. Carbapenem-hydrolyzing β-lactamases (also called carbapenemases), however, can confer bacterial resistance and represent a serious health threat. Here

Comprehensive analysis of protein digestion using six trypsins reveals the origin of trypsin as a significant source of variability in proteomics

October 11, 2013
Author(s)
Stephen E. Stein, Paul A. Rudnick, Scott J. Walmsley, Qian Dong, Alexey I. Nesvizhskii, Yuxue Liang
Trypsin is an endoprotease commonly used for sample preparation in proteomics experiments. Importantly, protein digestion is dependent on multiple factors, including the trypsin origin and digestion conditions. In-depth characterization of trypsin activity

Some Journal Metrics for Forensic Science International: Genetics

October 2, 2013
Author(s)
John M. Butler
Forensic Science International: Genetics, which is the official journal of the International Society for Forensic Genetics, has grown in readership and impact factor since its introduction in 2007. This article reviews some metrics of the 32 issues

Functionalization-Dependent Induction of Cellular Survival Pathways by CdSe Quantum Dots in Primary Normal Human Bronchial Epithelial Cells

September 5, 2013
Author(s)
Amber Nagy, Jennifer A. Hollingsworth, Bin Hu, Andrea Steinbruck, Peter C. Stark, Cristina Rios Valdez, Momchilo Vuyisich, Michael H. Stewart, Donald H. Atha, Bryant C. Nelson, Rashi Iyer
Quantum dots (QDs) are semiconductor nanocrystals exhibiting unique optical properties which can be exploited for many practical applications ranging from photovoltaics to biomedical imaging and drug delivery. They are increasingly manufactured in large

Measurement Uncertainty in Cell Image Segmentation Data Analysis

August 13, 2013
Author(s)
Jin Chu Wu, Michael W. Halter, Raghu N. Kacker, John T. Elliott, Anne L. Plant
Cell image segmentation is a part of quantitative studies regarding cell movement and cell behavior, and it plays a critical role in molecular biology and cellular biochemistry. Therefore, it is fundamentally important to evaluate the performance levels of

NIST Micronutrients Measurement Quality Assurance Program Summer 2007 Comparability Studies: Results for Round Robin LXII Fat-Soluble Vitamins and Carotenoids in Human Serum and Round Robin 27 Ascorbic Acid in Human Serum

August 5, 2013
Author(s)
David L. Duewer, Jeanice M. Brown Thomas
The National Institute of Standards and Technology coordinates the Micronutrients Measurement Quality Assurance Program (MMQAP) for laboratories that measure fat- and water-soluble vitamins and carotenoids in human serum and plasma. This report describes

NIST Micronutrients Measurement Quality Assurance Program Summer 2008 Comparability Studies: Results for Round Robin LXIV Fat-Soluble Vitamins and Carotenoids in Human Serum and Round Robin 29 Ascorbic Acid in Human Serum

August 5, 2013
Author(s)
David L. Duewer, Jeanice M. Brown Thomas
The National Institute of Standards and Technology coordinates the Micronutrients Measurement Quality Assurance Program (MMQAP) for laboratories that measure fat- and water-soluble vitamins and carotenoids in human serum and plasma. This report describes

NIST Micronutrients Measurement Quality Assurance Program Summer 2009 Comparability Studies: Results for Round Robin LXVI Fat-Soluble Vitamins and Carotenoids in Human Serum and Round Robin 31 Ascorbic Acid in Human Serum

August 5, 2013
Author(s)
David L. Duewer, Jeanice M. Brown Thomas
The National Institute of Standards and Technology coordinates the Micronutrients Measurement Quality Assurance Program (MMQAP) for laboratories that measure fat- and water-soluble vitamins and carotenoids in human serum and plasma. This report describes

NIST Micronutrients Measurement Quality Assurance Program Winter 2007 Comparability Studies: Results for Round Robin LXI Fat-Soluble Vitamins and Carotenoids in Human Serum and Round Robin 26 Ascorbic Acid in Human Serum

August 5, 2013
Author(s)
David L. Duewer, Jeanice M. Brown Thomas
The National Institute of Standards and Technology coordinates the Micronutrients Measurement Quality Assurance Program (MMQAP) for laboratories that measure fat- and water-soluble vitamins and carotenoids in human serum and plasma. This report describes

NIST Micronutrients Measurement Quality Assurance Program Winter 2008 Comparability Studies: Results for Round Robin LXIII Fat-Soluble Vitamins and Carotenoids in Human Serum and Round Robin 28 Ascorbic Acid in Human Serum

August 5, 2013
Author(s)
David L. Duewer, Jeanice M. Brown Thomas
The National Institute of Standards and Technology coordinates the Micronutrients Measurement Quality Assurance Program (MMQAP) for laboratories that measure fat- and water-soluble vitamins and carotenoids in human serum and plasma. This report describes

NIST Micronutrients Measurement Quality Assurance Program Winter 2009 Comparability Studies: Results for Round Robin LXV Fat-Soluble Vitamins and Carotenoids in Human Serum and Round Robin 30 Ascorbic Acid in Human Serum

August 5, 2013
Author(s)
David L. Duewer, Jeanice M. Brown Thomas
The National Institute of Standards and Technology coordinates the Micronutrients Measurement Quality Assurance Program (MMQAP) for laboratories that measure fat- and water-soluble vitamins and carotenoids in human serum and plasma. This report describes

NIST Micronutrients Measurement Quality Assurance Program Summer 2010 Comparability Studies: Results for Round Robin LXVIII Fat-Soluble Vitamins and Carotenoids in Human Serum and Round Robin 33 Ascorbic Acid in Human Serum

August 2, 2013
Author(s)
David L. Duewer, Jeanice M. Brown Thomas
The National Institute of Standards and Technology coordinates the Micronutrients Measurement Quality Assurance Program (MMQAP) for laboratories that measure fat- and water-soluble vitamins and carotenoids in human serum and plasma. This report describes

NIST Micronutrients Measurement Quality Assurance Program Winter 2010 Comparability Studies: Results for Round Robin LXVII Fat-Soluble Vitamins and Carotenoids in Human Serum and Round Robin 32 Ascorbic Acid in Human Serum

August 2, 2013
Author(s)
David L. Duewer, Jeanice M. Brown Thomas
The National Institute of Standards and Technology coordinates the Micronutrients Measurement Quality Assurance Program (MMQAP) for laboratories that measure fat- and water-soluble vitamins and carotenoids in human serum and plasma. This report describes
Displaying 626 - 650 of 1284
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