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Displaying 20101 - 20125 of 73963

Measuring Stem Cell Dimensionality in Tissue Scaffolds

April 1, 2014
Author(s)
Carl G. Simon Jr., Sapun Parekh, Christopher K. Tison, Girish Kumar, Tanya M. Farooque, Charles H. Camp
Many 3D scaffold systems have evolved for tissue engineering, drug screening and in vitro tissue models. However, it is not clear which scaffolds provide a 3D cell niche and there is no clear way to measure cell niche dimensionality. Advances in 3D niche

N-methylmesoporphyrin IX fluorescence as a reporter of strand orientation in guanine quadruplexes

April 1, 2014
Author(s)
Navin C. Sabharwal, Victoria Savikhin, Joshua Turek-Herman, John M. Nicoludis, Veronika Szalai, Liliya Yatsunyk
Guanine quadruplexes (GQ) are four-stranded DNA structures formed by guanine-rich DNA sequences. Formation of GQs inhibits cancer cell survival, but detecting GQs in vivo has proved difficult, in part because of GQ structural diversity. Development of GQ

Phase-Sensitive Small-Angle Neutron Scattering

April 1, 2014
Author(s)
Charles F. Majkrzak, Kathryn L. Krycka, Susan Krueger, Norman F. Berk, Paul A. Kienzle, Brian B. Maranville
A method is described for determining the neutron scattering length density distribution of a molecular scale object directly from phase-sensitive small angle neutron scattering (SANS). The structure factor amplitude is obtained through the use of a

Common-Path Method for Laser Tracker Ranging Calibration

March 31, 2014
Author(s)
Christopher J. Blackburn, Daniel S. Sawyer, Craig M. Shakarji
We present an alternative to the back-to-back method of testing laser tracker ranging systems. Our approach uses a common air path for both the measurement and reference laser beams. This technique allows for more accurate determination of the reference

Determination of the Planck constant using a watt balance with a superconducting magnet system at the National Institute of Standards and Technology

March 31, 2014
Author(s)
Stephan Schlamminger, Darine El Haddad, Frank C. Seifert, Leon S. Chao, David B. Newell, Richard L. Steiner, Jon R. Pratt
In the past two years measurements were performed with a watt balance at the National Institute of Standards and Technology (NIST) to determine the Planck constant. A detailed analysis of these measurements and their uncertainties led to a value of h=6.626

Hydrogen traps in the outgassing model of a stainless steel vacuum chamber

March 31, 2014
Author(s)
Robert F. Berg
This article describes a model for hydrogen outgassing into a stainless steel vacuum chamber. It accounts for the geometry of the chamber components, the hydrogen dissolved in those components, and the processes of diffusion, recombination, and trapping

Influence Of Sorbitol on Protein Crowding in Solution and Freeze-Concentrated Phases

March 31, 2014
Author(s)
Sheila Khodadadi, Nicholas James Clark, Arnold McAuley, Viviana Cristiglio, Joseph E. Curtis, Evgenyi Y. Shalaev, Susan T. Krueger
Protein stability during processing and storage is of great challenge for biotechnology and pharmaceutical industries. Polyhydroxy compounds are well-known cryo- and lyo-protectors, which minimize destabilization of proteins and biological systems during

Report of the 98th National Conference on Weights and Measures (2013)

March 31, 2014
Author(s)
Linda D. Crown, Tina G. Butcher, Richard A. Harshman, David A. Sefcik, Lisa Warfield
The 98th Annual Meeting of the National Conference on Weights and Measures (NCWM) was held July 14 to 18, 2013, at the Seelbach Hilton Louisville, Louisville, Kentucky. The theme of the meeting was “On the Path to Tomorrow.” Reports by the NCWM Board of

Quantum-noise-limited cavity ring-down spectroscopy

March 29, 2014
Author(s)
David A. Long, Adam J. Fleisher, Szymon S. Wojtewicz, Joseph T. Hodges
Spectroscopic techniques with ultra-high sensitivity allow for the study of a wide variety of physical and chemical phenomena, ranging from the interrogation of individual atoms1 and molecules2,3 to the quantitative extraction of ensemble properties from
Displaying 20101 - 20125 of 73963
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