January 26, 2023
      
                  
        
  Author(s)
  David Travis  Gallagher,   Biao  Ruan,   Yanan  He,   Yingwei  Chen,   Eun Jung  Choi,   Yihong  Chen,   Dana  Motabar,   Tsega  Solomon,   Richard  Simmerman,   Thomas  Kauffman,   John  Orban,   Philip  Bryan
 
       
            
    
    
        Protein sequences encoding three common small folds (3-alpha, beta-grasp, and alpha/beta plait) were connected in a network of mutational pathways that intersect at high-identity sequences, termed nodes. The structures of proteins around nodes were