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Michele M. Schantz, Carissa Powers, Schleicher Rosemary, Joseph Betz, Stephen A. Wise
The National Institute of Standards and Technology, in collaboration with the National Institutes of Health Office of Dietary Supplements and the Centers for Disease Control and Prevention, is conducting an accuracy-based program for improving the
Aaron Johnson, Iosif Isaakovich Shinder, Rodney A. Bryant, JohnPaul R. Abbott, Keith A. Gillis, Joey Boyd, James Filla, Michael R. Moldover
Accurate flow measurements are essential to quantify the amount of greenhouse gases (GHGs) and other pollutants emitted from power plant stacks. Although protocols have been developed, the uncertainty of stack flow measurements has not been documented.
Chih-Jian Lih, Robin D. Harrington, Kneshay Harper, David J. Sims, Paul McGregor, Corinne Camalier, Han Si, Biswajit Das, P. M. Williams, Hua-Jun He, Jamie L. Almeida, Steven Lund, Steven J. Choquette, Kenneth D. Cole
The National Institute of Standards and Technology (NIST) Standard Reference Materials 2373 is a set of genomic DNA samples prepared from five breast cancer cell lines with certified values for the ratio of the HER2 gene copy number to the copy numbers of
The last of the radium-226 standards that Marie Curie personally handled is destined for a radioactive materials waste dump. Presented here is a history of the standards and a challenge to the scientific community to present a rationale for why this
Stephen E. Long, Brittany L. Kassim, Ashley S. Boggs-Russell, Susan Tai, Stephen A. Wise
Iodine deficiency remains a significant global public health challenge. Analytical measurements are therefore made routinely to assess iodine intake from food and supplements, public health status and trends. The National Institute of Standards and
Amanda J. Moors, Rebecca S. Pugh, Jody R. Evans, Jennifer M. Ness, Debra L. Ellisor, Melannie J. Bachman
The NIST Reference Materials Production (RMP) Facility at the Hollings Marine Laboratory produces fresh, frozen powder materials which are used as Standard Reference Materials (SRMs) and Control Materials (CMs) from frozen biological, environmental
Justin Zook, John G. Cleary, Len Trigg, Francisco De La Vega
To evaluate and compare the performance of variant calling methods and confidence scores, comparisons between a test call set and a "gold standard" need to be carried out. Unfortunately, these comparisons are not straightforward with the current Variant
Vladimir L. Orkin, S. P. Sander, James B. Burkholder, J. P. D. Abbatt D. Abbatt, J. R. Barker, Robert E. Huie, C E. Kolb, Michael J. Kurylo III, David M. Wilmouth, P. H. Wine
Justin M. Zook, Jennifer H. McDaniel, David N. Catoe, Lindsay Harris, Marc L. Salit
The Genome in a Bottle Consortium hosted by the National Institute of Standards and Technology, (NIST), is creating reference materials and data for human genome sequencing, as well as methods for genome comparison and benchmarking. Here, we describe a
Walter G. McDonough, Sara Orski, Charles M. Guttman, Kalman Migler, Kathryn L. Beers
The National Institute of Standards and Technology (NIST) provides science, industry, and government with a central source of well-characterized materials certified for chemical composition or for some chemical or physical property. These materials are
A Regional Metrology Organization (RMO) Key Comparison of dew/frost point temperatures was carried out by the National Institute of Standards and Technology (NIST, USA) and the Laboratorio Costarricense de Metrología (LACOMET, Costa Rica) between February
Barbara J. Belzer, Kari K. Harper, Thomas R. Hettenhouser, Warren R. Merkel
NIST Handbook 150-2, 2016 edition, presents the technical requirements and guidance for the accreditation of laboratories under the National Voluntary Laboratory Accreditation Program (NVLAP) Calibration Laboratories Program. The 2016 edition of NIST
Kathryn E. Keenan, Karl F. Stupic, Michael A. Boss, Stephen E. Russek, Thomas L. Chenevert, Pottumarthi V. Prasad, Wilburn E. Reddick, Jie Zheng, Peng Hu, Edward F. Jackson
We used the ISMRM/NIST system phantom to assess variations of T1 measurements across MRI systems at 1.5 T and 3 T, to determine the repeatability and reproducibility of the T1 measurements. This study demonstrates that T1 variations from NMR-measured value
Michele M. Schantz, Danielle Cleveland, N. Alan Heckert, John Kucklick, Stefan D. Leigh, Stephen E. Long, Jennifer Lynch, Karen E. Murphy, Rabia Oflaz, Adam L. Pintar, Barbara J. Porter, Savelas A. Rabb, Stacy Schuur, Stephen Wise, Rolf L. Zeisler
Two new Standard Reference Materials (SRMs), SRM 2786 Fine Particulate Matter ( 4 µm) and SRM 2787 Fine Particulate Matter ( 10 µm) have been developed in support of the US Environmental Protection Agency's National Ambient Air Quality Standards for
Nathanael D. Olson, Justin M. Zook, Daniel V. Samarov, Scott A. Jackson, Marc L. Salit
The rapid adoption of microbial whole genome sequencing in public health, clinical testing, and forensic labo-ratories requires the use of validated and well characterized measurement processes. Reference materials thatare well characterized and
David W. Allen, Elmer T. Slonecker, Ronald G. Resmini
Remote sensing science is currently undergoing a tremendous expansion in the area of hyperspectral imaging (HSI) technology. Spurred largely by the explosive growth of Unmanned Aerial Vehicles (UAV), sometimes called Unmanned Aircraft Systems (UAS), or
Consisting of a 1 m long piece of 0.5 mm diameter platinum wire, SRM 1967a meets the requirements for a thermoelectric reference material for temperatures from 196 °C up to approximately 1700 °C. We have tested the thermoelectric emf of four SRM 1967a
Justin M. Zook, James Priest, Rachel Goldfeder, Megan Grove, Daryl Waggott, Matthew Wheeler, Euan Ashley, Marc L. Salit
As next-generation sequencing is becoming routinely applied to clinical care, the predictive characteristics and limitations of whole exome and whole genome sequencing need to be well-understood. The Genome in a Bottle Consortium has recently published a
Jorge O. Ona Ruales, Ruiz-Morales Yosadara, Stephen A. Wise
A methodology for the characterization of groups of PAHs using a combination of Normal Phase Liquid Chromatography with Ultraviolet-Visible Spectroscopy (NPLC/UV-vis) and Gas Chromatography with Mass Spectrometry (GC/MS) was used for the identification and
Brian E. Zimmerman, Denis E. Bergeron, Ryan P. Fitzgerald, Jeffrey T. Cessna
Tests for chemical stability were carried out on carrier-added 68Ge solutions prepared and calibrated in 2007 and 2011 to evaluate the suitability of the specific composition as a potential Standard Reference Material. Massic count rates of the stored
Jeffrey W. Hudgens, Richard Y. Huang, Emma D'Ambro
The chapter examines method validation and measurement standards for measuring protein dynamics by hydrogen/deuterium exchange mass spectrometry. Topics examined include the rationale for a reference measurement system for HDX-MS, attaining high accuracy
George C. Rhoderick, Duane Kitzis, Michael E. Kelley, Walter R. Miller Jr., Bradley Hall, Edward Dlugokencky, Pieter Tans, Antonio M. Possolo, Jennifer Carney
The National Institute of Standards and Technology (NIST) recently began to develop standard mixtures of greenhouse gases as part of a broad program mandated by the 2009 United States Congress to support research in climate change. To this end, NIST made
Aaron N. Johnson, Rodney A. Bryant, Tamae M. Wong, James R. Whetstone, Eric Harman, Woong Kang, Keith A. Gillis, Hsin-Hung Lee, Iosif I. Shinder, Liang Zhang
On April 20-21, 2015, NIST hosted a workshop that, through measurement science, enabled the owners of stationary sources (primarily the electric power industry) and their regulatory agencies (federal and state) to better characterize greenhouse gas (GHG)