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Displaying 226 - 250 of 528

Standard Operation Procedures (SOPs) for the Palla VM-KT Vibrating Cryomill: Production of Fresh Frozen Standard Reference and Control Materials (SRMs/CMs) at the NIST Reference Material Production Facility

August 11, 2016
Author(s)
Amanda J. Moors, Rebecca S. Pugh, Jody R. Evans, Jennifer M. Ness, Debra L. Ellisor, Melannie J. Bachman
The NIST Reference Materials Production (RMP) Facility at the Hollings Marine Laboratory produces fresh, frozen powder materials which are used as Standard Reference Materials (SRMs) and Control Materials (CMs) from frozen biological, environmental

Extensive sequencing of seven human genomes to characterize benchmark reference materials

June 7, 2016
Author(s)
Justin M. Zook, Jennifer H. McDaniel, David N. Catoe, Lindsay Harris, Marc L. Salit
The Genome in a Bottle Consortium hosted by the National Institute of Standards and Technology, (NIST), is creating reference materials and data for human genome sequencing, as well as methods for genome comparison and benchmarking. Here, we describe a

STANDARD REFERENCE MATERIALS FOR THE POLYMERS INDUSTRY

May 24, 2016
Author(s)
Walter G. McDonough, Sara Orski, Charles M. Guttman, Kalman Migler, Kathryn L. Beers
The National Institute of Standards and Technology (NIST) provides science, industry, and government with a central source of well-characterized materials certified for chemical composition or for some chemical or physical property. These materials are

National Voluntary Laboratory Accreditation Program (NVLAP) Calibration Laboratories

May 10, 2016
Author(s)
Barbara J. Belzer, Kari K. Harper, Thomas R. Hettenhouser, Warren R. Merkel
NIST Handbook 150-2, 2016 edition, presents the technical requirements and guidance for the accreditation of laboratories under the National Voluntary Laboratory Accreditation Program (NVLAP) Calibration Laboratories Program. The 2016 edition of NIST

Comparison of T1 measurement using ISMRM/NIST system phantom

May 9, 2016
Author(s)
Kathryn E. Keenan, Karl F. Stupic, Michael A. Boss, Stephen E. Russek, Thomas L. Chenevert, Pottumarthi V. Prasad, Wilburn E. Reddick, Jie Zheng, Peng Hu, Edward F. Jackson
We used the ISMRM/NIST system phantom to assess variations of T1 measurements across MRI systems at 1.5 T and 3 T, to determine the repeatability and reproducibility of the T1 measurements. This study demonstrates that T1 variations from NMR-measured value

Development of Two Fine Particulate Matter Standard Reference Materials ( 4 mm and 10 mm) for the Determination of Organic and Inorganic Constituents

April 13, 2016
Author(s)
Michele M. Schantz, Danielle Cleveland, N. Alan Heckert, John Kucklick, Stefan D. Leigh, Stephen E. Long, Jennifer Lynch, Karen E. Murphy, Rabia Oflaz, Adam L. Pintar, Barbara J. Porter, Savelas A. Rabb, Stacy Schuur, Stephen Wise, Rolf L. Zeisler
Two new Standard Reference Materials (SRMs), SRM 2786 Fine Particulate Matter ( 4 µm) and SRM 2787 Fine Particulate Matter ( 10 µm) have been developed in support of the US Environmental Protection Agency's National Ambient Air Quality Standards for

PEPR: Pipeline for Evaluating Prokaryotic References

April 1, 2016
Author(s)
Nathanael D. Olson, Justin M. Zook, Daniel V. Samarov, Scott A. Jackson, Marc L. Salit
The rapid adoption of microbial whole genome sequencing in public health, clinical testing, and forensic labo-ratories requires the use of validated and well characterized measurement processes. Reference materials thatare well characterized and

Towards Establishing Compact Imaging Spectrometer Standards

March 31, 2016
Author(s)
David W. Allen, Elmer T. Slonecker, Ronald G. Resmini
Remote sensing science is currently undergoing a tremendous expansion in the area of hyperspectral imaging (HSI) technology. Spurred largely by the explosive growth of Unmanned Aerial Vehicles (UAV), sometimes called Unmanned Aircraft Systems (UAS), or

SRM 1967a: High-Purity Platinum Thermoelement

March 9, 2016
Author(s)
Karen M. Garrity, Weston L. Tew, Dean C. Ripple
Consisting of a 1 m long piece of 0.5 mm diameter platinum wire, SRM 1967a meets the requirements for a thermoelectric reference material for temperatures from 196 °C up to approximately 1700 °C. We have tested the thermoelectric emf of four SRM 1967a

Clinical Implications of Technical Performance in Medical Genome Sequencing

March 2, 2016
Author(s)
Justin M. Zook, James Priest, Rachel Goldfeder, Megan Grove, Daryl Waggott, Matthew Wheeler, Euan Ashley, Marc L. Salit
As next-generation sequencing is becoming routinely applied to clinical care, the predictive characteristics and limitations of whole exome and whole genome sequencing need to be well-understood. The Genome in a Bottle Consortium has recently published a

Identification and Quantification of Seven Fused Aromatic Rings C26H14 Peri-Condensed Benzenoid Polycyclic Aromatic Hydrocarbons in a Complex Mixture of Polycyclic Aromatic Hydrocarbons from Coal Tar

March 2, 2016
Author(s)
Jorge O. Ona Ruales, Ruiz-Morales Yosadara, Stephen A. Wise
A methodology for the characterization of groups of PAHs using a combination of Normal Phase Liquid Chromatography with Ultraviolet-Visible Spectroscopy (NPLC/UV-vis) and Gas Chromatography with Mass Spectrometry (GC/MS) was used for the identification and

Long-term stability of carrier-added Ge-68 standardized solutions

March 1, 2016
Author(s)
Brian E. Zimmerman, Denis E. Bergeron, Ryan P. Fitzgerald, Jeffrey T. Cessna
Tests for chemical stability were carried out on carrier-added 68Ge solutions prepared and calibrated in 2007 and 2011 to evaluate the suitability of the specific composition as a potential Standard Reference Material. Massic count rates of the stored

Method Validation and Standards in Hydrogen/Deuterium Exchange Mass Spectrometry

March 1, 2016
Author(s)
Jeffrey W. Hudgens, Richard Y. Huang, Emma D'Ambro
The chapter examines method validation and measurement standards for measuring protein dynamics by hydrogen/deuterium exchange mass spectrometry. Topics examined include the rationale for a reference measurement system for HDX-MS, attaining high accuracy

Development of a Northern Continental Air Standard Reference Material

February 18, 2016
Author(s)
George C. Rhoderick, Duane Kitzis, Michael E. Kelley, Walter R. Miller Jr., Bradley Hall, Edward Dlugokencky, Pieter Tans, Antonio M. Possolo, Jennifer Carney
The National Institute of Standards and Technology (NIST) recently began to develop standard mixtures of greenhouse gases as part of a broad program mandated by the 2009 United States Congress to support research in climate change. To this end, NIST made

Measurement Challenges and Metrology for Monitoring CO2 Emissions from Smokestacks Workshop Summary

January 20, 2016
Author(s)
Aaron N. Johnson, Rodney A. Bryant, Tamae M. Wong, James R. Whetstone, Eric Harman, Woong Kang, Keith A. Gillis, Hsin-Hung Lee, Iosif I. Shinder, Liang Zhang
On April 20-21, 2015, NIST hosted a workshop that, through measurement science, enabled the owners of stationary sources (primarily the electric power industry) and their regulatory agencies (federal and state) to better characterize greenhouse gas (GHG)

SVClassify: a method to use multiple datasets to classify candidate structural variants into true positives and false positives

January 16, 2016
Author(s)
Justin M. Zook, Hemang M. Parikh, Desu Chen, Hariharan K. Iyer, Marc L. Salit, Wolfgang Losert
The human genome contains variants ranging in size from small single nucleotide polymorphisms (SNPs) to large structural variants (SVs). While high-quality benchmark small variant calls have recently been developed by the Genome in a Bottle Consortium, no

ASTM Workshop on Standards & Measurements for Tissue Engineering Scaffolds

January 1, 2016
Author(s)
Carl G. Simon Jr., John Test, Michael Yaszemski, Reto Luginbuehl, Anthony Ratcliffe, Paul Tomlins
A “Workshop on Standards & Measurements for Tissue Engineering Scaffolds” was held on May 21, 2013 and was sponsored by the American Society of Testing and Materials International (ASTM International) in Indianapolis, IN. The purpose of the workshop was to

Potential Stable Low-Permeation Rate Standard Based on Micro-machined Silicon

December 15, 2015
Author(s)
Grady S. White, Adrian Verwolf, Chris M. Poling, Nicholas Barbosa, Nikki S. Rentz
Silicon wafers with micro-machined holes were evaluated for use as low permeation standard artifacts. Accuracy, stability, and reliability were assessed. Two experimental techniques were used: chilled mirror hygrometer and mass loss. The wafers exhibited a
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