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Standards

Reference materials

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Displaying 226 - 250 of 538

Transmission Electron Microscope Calibration Methods for Critical Dimension Standards

October 13, 2016
Author(s)
Ndubuisi G. Orji, Ronald G. Dixson, Domingo I. Garcia-Gutierrez, Bunday Benjamin, M R. Bishop, Michael W. Cresswell, Richard A. Allen, John Allgair
One of the key challenges in critical dimension (CD) metrology is finding suitable dimensional calibration standards. The transmission electron microscope (TEM), which produces lattice-resolved images having scale traceability to the SI (International

THE NIST MAGNETIC SUSPENSION MASS COMPARATOR: A LOOK AT AUTOMATION

September 29, 2016
Author(s)
Corey A. Stambaugh, Edward C. Mulhern
The magnetic suspension mass comparator at NIST is a fully automated mass comparator with the unique feature that it is able to directly compare a mass in vacuum to one in air. The technique is realized by coupling a weighing pan located in air to a mass

Volume Determination of Irregularly-shaped Quasi-spherical Nanoparticles

September 22, 2016
Author(s)
Ravikiran Attota
Nanoparticles (NPs) are widely used in diverse application areas, such as medicine, engineering, and cosmetics. The size (or volume) of NPs is one of the most important parameters for their successful application. It is relatively straightforward to

Interlaboratory Analytical Comparison of Fatty Acid Concentrations in Serum or Plasma

September 20, 2016
Author(s)
Michele M. Schantz, Carissa Powers, Schleicher Rosemary, Joseph Betz, Stephen A. Wise
The National Institute of Standards and Technology, in collaboration with the National Institutes of Health Office of Dietary Supplements and the Centers for Disease Control and Prevention, is conducting an accuracy-based program for improving the

NIST Programs to Advance Accurate, Internationally-Recognized Stack Emissions Measurements

September 15, 2016
Author(s)
Aaron Johnson, Iosif Isaakovich Shinder, Rodney A. Bryant, JohnPaul R. Abbott, Keith A. Gillis, Joey Boyd, James Filla, Michael R. Moldover
Accurate flow measurements are essential to quantify the amount of greenhouse gases (GHGs) and other pollutants emitted from power plant stacks. Although protocols have been developed, the uncertainty of stack flow measurements has not been documented. 

Certified DNA Reference Materials to Compare HER2 Gene Amplification Measurements Using Next- Generation Sequencing Methods

September 1, 2016
Author(s)
Chih-Jian Lih, Robin D. Harrington, Kneshay Harper, David J. Sims, Paul McGregor, Corinne Camalier, Han Si, Biswajit Das, P. M. Williams, Hua-Jun He, Jamie L. Almeida, Steven Lund, Steven J. Choquette, Kenneth D. Cole
The National Institute of Standards and Technology (NIST) Standard Reference Materials 2373 is a set of genomic DNA samples prepared from five breast cancer cell lines with certified values for the ratio of the HER2 gene copy number to the copy numbers of

Marie Curies Last Radium Standard Grand Challenge

September 1, 2016
Author(s)
Bert M. Coursey
The last of the radium-226 standards that Marie Curie personally handled is destined for a radioactive materials waste dump. Presented here is a history of the standards and a challenge to the scientific community to present a rationale for why this

Standard Operation Procedures (SOPs) for the Palla VM-KT Vibrating Cryomill: Production of Fresh Frozen Standard Reference and Control Materials (SRMs/CMs) at the NIST Reference Material Production Facility

August 11, 2016
Author(s)
Amanda J. Moors, Rebecca S. Pugh, Jody R. Evans, Jennifer M. Ness, Debra L. Ellisor, Melannie J. Bachman
The NIST Reference Materials Production (RMP) Facility at the Hollings Marine Laboratory produces fresh, frozen powder materials which are used as Standard Reference Materials (SRMs) and Control Materials (CMs) from frozen biological, environmental

Extensive sequencing of seven human genomes to characterize benchmark reference materials

June 7, 2016
Author(s)
Justin M. Zook, Jennifer H. McDaniel, David N. Catoe, Lindsay Harris, Marc L. Salit
The Genome in a Bottle Consortium hosted by the National Institute of Standards and Technology, (NIST), is creating reference materials and data for human genome sequencing, as well as methods for genome comparison and benchmarking. Here, we describe a

STANDARD REFERENCE MATERIALS FOR THE POLYMERS INDUSTRY

May 24, 2016
Author(s)
Walter G. McDonough, Sara Orski, Charles M. Guttman, Kalman Migler, Kathryn L. Beers
The National Institute of Standards and Technology (NIST) provides science, industry, and government with a central source of well-characterized materials certified for chemical composition or for some chemical or physical property. These materials are

National Voluntary Laboratory Accreditation Program (NVLAP) Calibration Laboratories

May 10, 2016
Author(s)
Barbara J. Belzer, Kari K. Harper, Thomas R. Hettenhouser, Warren R. Merkel
NIST Handbook 150-2, 2016 edition, presents the technical requirements and guidance for the accreditation of laboratories under the National Voluntary Laboratory Accreditation Program (NVLAP) Calibration Laboratories Program. The 2016 edition of NIST

Comparison of T1 measurement using ISMRM/NIST system phantom

May 9, 2016
Author(s)
Kathryn E. Keenan, Karl F. Stupic, Michael A. Boss, Stephen E. Russek, Thomas L. Chenevert, Pottumarthi V. Prasad, Wilburn E. Reddick, Jie Zheng, Peng Hu, Edward F. Jackson
We used the ISMRM/NIST system phantom to assess variations of T1 measurements across MRI systems at 1.5 T and 3 T, to determine the repeatability and reproducibility of the T1 measurements. This study demonstrates that T1 variations from NMR-measured value

Development of Two Fine Particulate Matter Standard Reference Materials ( 4 mm and 10 mm) for the Determination of Organic and Inorganic Constituents

April 13, 2016
Author(s)
Michele M. Schantz, Danielle Cleveland, N. Alan Heckert, John Kucklick, Stefan D. Leigh, Stephen E. Long, Jennifer Lynch, Karen E. Murphy, Rabia Oflaz, Adam L. Pintar, Barbara J. Porter, Savelas A. Rabb, Stacy Schuur, Stephen Wise, Rolf L. Zeisler
Two new Standard Reference Materials (SRMs), SRM 2786 Fine Particulate Matter ( 4 µm) and SRM 2787 Fine Particulate Matter ( 10 µm) have been developed in support of the US Environmental Protection Agency's National Ambient Air Quality Standards for

PEPR: Pipeline for Evaluating Prokaryotic References

April 1, 2016
Author(s)
Nathanael D. Olson, Justin M. Zook, Daniel V. Samarov, Scott A. Jackson, Marc L. Salit
The rapid adoption of microbial whole genome sequencing in public health, clinical testing, and forensic labo-ratories requires the use of validated and well characterized measurement processes. Reference materials thatare well characterized and

Towards Establishing Compact Imaging Spectrometer Standards

March 31, 2016
Author(s)
David W. Allen, Elmer T. Slonecker, Ronald G. Resmini
Remote sensing science is currently undergoing a tremendous expansion in the area of hyperspectral imaging (HSI) technology. Spurred largely by the explosive growth of Unmanned Aerial Vehicles (UAV), sometimes called Unmanned Aircraft Systems (UAS), or

SRM 1967a: High-Purity Platinum Thermoelement

March 9, 2016
Author(s)
Karen M. Garrity, Weston L. Tew, Dean C. Ripple
Consisting of a 1 m long piece of 0.5 mm diameter platinum wire, SRM 1967a meets the requirements for a thermoelectric reference material for temperatures from 196 °C up to approximately 1700 °C. We have tested the thermoelectric emf of four SRM 1967a

Clinical Implications of Technical Performance in Medical Genome Sequencing

March 2, 2016
Author(s)
Justin M. Zook, James Priest, Rachel Goldfeder, Megan Grove, Daryl Waggott, Matthew Wheeler, Euan Ashley, Marc L. Salit
As next-generation sequencing is becoming routinely applied to clinical care, the predictive characteristics and limitations of whole exome and whole genome sequencing need to be well-understood. The Genome in a Bottle Consortium has recently published a
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