In this device solutions are forced into a specially designed mixing chamber. After a time, perhaps as short as a few ms, the solution is pushed into the sample cell at a time recorded using the master clock. Thus, this device will allow automated sample preparation to be done on a time scale matching those accessible to vSANS and CANDOR and provide the time resolution necessary to characterize the kinetics of, for example, the formation of biocomplexes.
The in-house-built stopped flow apparatus has improved its time resolution from ~3 second to about 1 second with a remaining goal of reaching ~400 ms. This benchmark should be achievable once we receive the high-pressure neutron scattering cell that was procured with the commercial stopped-flow system (eta Feb 2023).
Lilo Pozzo – Washington; Ron Jones – NIST; Norm Wagner – Delaware; Drew Marquardt– Windsor; Sarah Rodgers–RAL; Adrian Rennie– Uppsala Andy Church–RAL; Lionel Porcar– ILL