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Katrice Lippa

Katrice presently serves as Group Leader for the Organic Chemical Measurement Science Group at the National Institute of Standards and Technology (NIST). The group develops and promotes Standard Reference Materials and Data products for organic species in clinical and metabolomics, food and nutritional assessment, chemical manufacturing and forensics project areas; maintains high resolution mass spectrometry, enantioselective and multidimensional separation procedures, vibrational and nuclear magnetic resonance spectroscopy facilities and expertise for analyses at trace and ultratrace concentration levels; provides advice and measurement services to other government agencies (federal and state), scientific organizations, and American industry; and interacts with international standards organizations and other National Metrology Institutes (NMIs) to establish comparability of measurement capabilities.

Her current research directions are in quantitative NMR techniques for the characterization of pure substances as well as organic constituents in biological and natural matrices, in addition to advancing metrologically-sound methods for ensuring chemical traceability. As a research analytical chemist, Katrice has extensive experience in trace-level organic measurement techniques (chromatography-mass spectrometry) and implementation of structure-reactivity/molecular modeling tools to help solve chemical measurement problems. She also has expertise in interlaboratory comparisons and coordination of the Division’s Quality Assurance Programs (QAPs). She also represents NIST in the InterAmerican Metrology System (SIM) and the Consultative Committee for Amount of Substance – Metrology in Chemistry (CCQM) to develop metrology tools for traceability and to establish equivalence among measurements made by NMIs.


Covalently Immobilized Fluorinated Carboxylic Acid Stationary Phase for Liquid Chromatography (U.S. Patent No. 7,794,837 B2; Sep. 14, 2010)


  • Allen V. Astin Measurement Science Award, Department of Commerce (2018)
  • Department of Commerce Bronze Medal Award, National Institute of Standards and Technology (2018)
  • Material Measurement Laboratory Technical Outreach Award, National Institute of Standards and Technology (2017)
  • National Research Council Postdoctoral Research Fellow, 2002
  • Young Scientist Research Award, Division of Agrochemicals, American Chemical Society, 2000
  • Graduate Student Award in Environmental Chemistry, American Chemical Society, 2000
  • Dissertation Fellow, American Association of University Women Education Foundation, 1999
  • Undergraduate Award in Analytical Chemistry, American Chemical Society, 1991

Membership and Professional Activities

  • American Chemical Society
  • AOAC International


Metabolomics Test Materials for Quality Control: A Study of a Urine Materials Suite

Dan Bearden, David A. Sheen, Yamil Simon, Bruce A. Benner Jr., Werickson Fortunato de Carvalho Rocha, Niksa Blonder, Katrice A. Lippa, Richard Beger, Laura Schnackenberg, Jinchun Sun, Khyati Mehta, Amrita Cheema, Haiwei Gu, Ramesh Marupaka, Nagana Gowda, Daniel Raftery
There is a lack of experimental reference materials and standards for metabolomics measurements, such as urine, plasma, and other human fluid samples. Reasons

Towards quality assurance and quality control in untargeted metabolomics studies

Richard Beger, Warwick Dunn, Abbas Bandukwala, Bianca Bethan, David Broadhurst, Clary Clish, Surendra Dasari, Leslie Derr, Annie Evans, Steve Fischer, Thomas Flynn, Thomas Hartung, David Herrington, Richard Higashi, Ping-Ching Hsu, Christina M. Jones, Maureen Kachman, Helen Karuso, Gary Kruppa, Katrice A. Lippa, Padma Maruvada, Jonathan Mosley, Ionna Ntai, Clair O?Donovan, Mary Playdon, Daniel Raftery, Daniel Shaughnessy, Amanda Souza, Timothy Spaeder, Barbara Spalholz, Mukesh Verma, Tilman Walk, Ian Wilson, Daniel Bearden, Krista Zanetti
We describe here the agreed upon first development steps and priority objectives of a community engagement effort to address current challenges in quality
Created October 9, 2019, Updated November 27, 2019