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Jacob Majikes (Fed)

Jacob Majikes is a Research Scientist in the Microsystems and Nanotechnology Division. He received his B.S. and Ph.D. in materials science and engineering from North Carolina State University. His doctoral research focused on probing the folding/assembly of DNA origami nanostructures. Jacob is working with Alex Liddle to develop metrics to quantify the yield of discrete DNA nanostructures and to understand the effect of structure design on yield.

Selected Publications

  • Competitive annealing of multiple DNA origami: formation of chimeric origami, J.M. Majikes, J.A. Nash, T.H. Labean, New Journal of Physics, 18, 115001 (20016)
  • Search for effective chemical quenching to arrest molecular assembly and directly monitor DNA nanostructure formation, J.M. Majikes, J.A. Nash, T.H. Labean,, Nanoscale, 1637-1644 (2016)

Publications

DNA Origami Design: A How-To Tutorial

Author(s)
Jacob Majikes, James Alexander Liddle
While the design and assembly of DNA origami are straightforward, its relative novelty as a nanofabrication technique means that the tools and methods for

Patents

DNA NANOTECHNOLOGY-BASED BIOMARKER MEASUREMENT PLATFORM

NIST Inventors
Arvind Balijepalli and Jacob Majikes
patent description The invention will allow precise colocalization of analyte-binding/signal-amplification motifs for easier characterization, as well as the ability to tune, for individual motifs, the binding affinity. This capability will greatly reduce the error rates of the measurements
Created July 30, 2019, Updated December 8, 2022