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Physics

Radiation

Projects/Programs

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Medical (Archive): Calibrations of Large-Volume, Solid Ge-68 Phantom Sources for Monitoring PET Scanner Performance in Clinical Trials

Completed

Although the data from most PET studies are often used on a relative basis, the quality of the analysis will be greatly improved if the data can be normalized using a common reference standard that allows instrumental variability to be minimized. This requires long-lived PET phantoms to be available

Medical (Archive): Small-field Therapy Dosimetry Studies Using Alanine/EPR

Completed

Developments in radiotherapy have significantly increased the use of small fields in stereotactic procedures and IMRT fields composed of small fields. Ionization chambers are not always suitable where situations of high dose gradients, time-dose variance, and non-uniform beam distributions are

Medical (Archive): Workshop for Radiobiology Dosimetry Standardization

Completed

Workshop Agenda with Presentations RADIATION DOSE IS MORE THAN A NUMBER! National Institute of Standards and Technology 100 Bureau Drive, Gaithersburg, MD Green Auditorium September 15 and 16, 2011 THURSDAY, SEPTEMBER 15, 2011 Welcome and Introduction Lisa Karam, NIST Bert Maidment, NIAID Norm

Medical: Calibrated Phantoms for Monitoring PET and SPECT Scanner Performance in Clinical Trials

Ongoing

Although the data from most PET and SPECT studies are often used on a relative basis, the quality of the analysis will be greatly improved if the data can be normalized using a common reference standard that allows instrumental variability to be minimized. This requires long-lived phantoms to be

Medical: Characterization of Dosimeters Used in Computed Tomography

Completed

The Dosimetry Group of the Radiation Physics Division has an on-going collaboration with the FDA, NIH, and the Walter Reed National Military Medical Center to characterize clinical dosimeters for the purpose of monitoring the radiation dose delivered to patients during computed tomography (CT) exams

Medical: Printed 2D phantoms with traceable activity for autoradiography calibrations

Ongoing

Exciting advances in precision cancer therapy use chemical targeting to deliver alpha-emitting radionuclides to tumor sites. There, the high energy and short range of alpha particles means the tumor is killed while neighboring healthy tissue is spared. This is targeted alpha therapy (TAT). While the

Medical: Standards for Clinical Radionuclide Calibrators

Ongoing

In nuclear medicine, clinical activity measurements are typically made using commercially available radionuclide calibrators (also referred to as “dose calibrators”) which incorporate a reentrant 4π ionization chamber and an electrometer. The current measured by these calibrators is translated into

New Reference Standards for Digital Mammography

Ongoing

These beams will provide FDA inspectors, ionization chamber manufacturers, and calibration facilities with the spectra that best represent what is used in clinics. These new reference radiation techniques will be available for calibrations and the FDA-MQSA proficiency tests. The beam parameters are

Dosimetry_ResearchandMetrology_PhotonAbsorbedDose_pic_Tosh

Photon Absorbed-Dose-to-Water Primary Standards

Ongoing

Modeling of accumulated-dose dependence in the heat defect of H2/O2 exhibits expected peak behavior in qualitative agreement with experiment, and is being further refined for purposes of reducing the associated relative uncertainty from its present value of 0.3 %. Studies to quantify the possible

Photonic Dosimetry

Ongoing

With this effort, NIST is responding to industry needs for traceable, measurement solutions that can resolve spatial variations of absorbed dose at the level of individual components on a silicon wafer or bacteria on surgical instruments. Presently, there is only limited traceability to national

Radiation Protection: Support of the Navy Dosimetry Program

Ongoing

Since 2010, the U.S. Navy has adopted a personal dosimeter designated as the model DT-702/PD, which was demonstrated to have an improved accuracy, energy discrimination and a lower detection limit than prior Navy designated models such as the DT-5XX/PD and DT-6XX/PD series. This dosimeter is used to

Radioanalytical Metrology

Ongoing

The Group engages in a wide range of methods applicable to the detection and characterization of nuclear materials. The work can benefit environmental studies, waste remediation, naturally occurring radioactivity detection and characterization and general radioanalytical metrology. Expertise in

Security: Air-Kerma Measurements in High Energy X-ray Beams

Completed

X rays are used for imaging the contents of vehicles and cargo. Because of the need to penetrate through the thickness of the wall of containers and vehicles in addition to the objects contained within, these systems rely on the use of penetrating radiation such as high energy megavoltage x rays

Security (archive): X-ray Systems for Cargo and Vehicle Inspection Systems

Completed

The American National Standards Institute (ANSI) standard for the image quality indicators of non-intrusive cargo and vehicle inspection systems, ANSI N42.46, was previously developed through a series of meetings hosted by NIST. NIST has conducted and analyzed the results of tests using this

Security: Nuclear Forensics Reference Material (RM) Program

Ongoing

NIST coordinates the production and characterization of nuclear forensics reference materials (NFRMs), which are vital for making precise and accurate measurements of nuclear materials. These materials will help ensure that measurements of nuclear material evidence are highly reliable, are traceable

Security: Standards Development for Detection of Illicit Trafficking of Radioactive

Ongoing

NIST is also working with the Department of Homeland Security (DHS) Domestic Nuclear Detection Office (DNDO) in the development of technical capability standards to address instrument performance against threat level sources. NIST is working with DNDO and the Joint Research Center (JRC) in the

Standard Reference Materials: Standardization of ²³²U (SRM 4324c)

Ongoing

The certified massic activity for 232U was obtained by 4παβ LS spectrometry with two commercial LS counters. The beta detection efficiencies for the 232U daughters were calculated using the MICELLE2 code for the CIEMAT/NIST efficiency tracing (CNET) method with composition-matched LS cocktails of a

Standard Reference Materials: Standardization of ²³⁹Pu (SRM 4330d)

Ongoing

The certified massic activity for 239Pu was obtained by 4πα liquid scintillation (LS) spectrometry with two commercial LS counters. Confirmatory measurements were performed by LS counting comparative measurements against SRM 4330d, which was also standardized in 2009 by 4pa liquid scintillation (LS)

Standard Reference Materials: Standardization of ²⁴³Am (SRM 4332f)

Ongoing

The certified massic activity for 243Am was obtained by 4παβ LS spectrometry with two commercial LS counters. The beta detection efficiencies for the 243Am daughter ( 239Np) were calculated using the CN2003 code for the CIEMAT/NIST efficiency tracing (CNET) method with composition-matched LS

example of light propagating with different values of OAM

Structure Neutron Waves: Generating and Detecting Neutrons with Orbital Angular Momentum

Ongoing

Light, electrons, and even atoms can be imparted with well-defined orbital angular momentum (OAM) which is often described as a ‘twisting’ or helical wavefront (see Fig. 1) as the particle propagates through space. These structured waves have found applications in optical tweezers, quantum

Traceability for Industrial Irradiators: Design of the Applied Irradiation Manufacturing Standards (AIMS) Facility

Ongoing

The foundation for validation and process control in irradiation applications is the measurement of absorbed dose and improvements to measurement quality can only come from understanding and controlling the influence quantities (i.e., time, temperature and environmental factors) that are ever

Transfer and working standard radiometers and photometers

Ongoing

Reflectance-type silicon trap-detectors – Silicon trap-detectors have been developed for use as transfer standards for the IR-SIRCUS and IR-Laser Scatter and Detector Characterization facilities. They are built using either Hamamatsu S6337 or S1337 photodiodes. UV silicon trap-detectors have also

X-ray computed tomography (CT) for medical applications

Completed

As scale lengths get smaller, diffraction becomes increasingly prominent in tomography. The work here develops diffraction tomography for laboratory sources. A new laboratory scale instrument at NIST/Boulder is dedicated to tomography of integrated circuit interconnects. Tomography software written

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