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Chemistry

Analytical chemistry

Projects/Programs

Keyword

Organizational Unit

Consistency Analysis and Uncertainty in ‘omic Data

Ongoing

As ‘omics moves into industrial and commercial applications, there is a need for quality and process control to ensure safety and efficacy of products and

Continuing Support of Cement Manufacturing

Ongoing

Cement manufacturers and their customers rely on the NIST Portland cement SRMs for laboratory qualification under ASTM International C 114-07 Standard Test

Determinations of Boron Deposit Quality by Neutron Depth Profiling

Ongoing

Straw detectors are a new concept in position-sensitive neutron detectors recently developed by Proportion Technology Inc. The detectors are especially valuable

Development of Methods for Measurement of Vitamin D and its Metabolites in Foods, Fortified Foods, and Dietary Supplements

Ongoing

Vitamin D is a fat-soluble vitamin that is essential for bone health. Vitamin D deficiency is associated with muscle weakness and osteoporosis and can

Development of Proteomics-Based Methods for Protein Quantification

Ongoing

NIST is developing methods for the quantification of clinically-relevant protein biomarkers by mass spectrometry. Some methods are intended to establish

Development of Reference Measurement Procedures and Reference Materials for Creatinine

Ongoing

Chronic kidney disease (CKD) is a growing problem in the U.S., and current estimates suggest that more than 20 million Americans are affected by this disease

Development of Reference Methods and Reference Materials for the Determination of Cardiac Troponin I in Human Serum

Ongoing

Cardiac troponin I (cTnI) is considered the 'gold standard' for the diagnosis of myocardial infarction and the assessment of cardiac damage. Yet this clinical

Development of Reference Methods and Reference Materials for Proteins

Ongoing

A number of proteins show promise as potential markers of health or disease, and commercial assays are being developed for these proteins. For example

Development of Reference Methods and Reference Materials for the Determination of Hormones in Human Serum

Ongoing

Hormones are chemical messengers that regulate many life functions, and deviations from normal levels can indicate serious health problems. Measurement of

Development of SRM 955c Toxic Elements in Caprine Blood

Completed

Environmental and occupational exposure to toxic metals is assessed through whole blood analysis. Due to advances in instrument technology, clinical

Development of Standards for the World Meteorological Organization, Global Atmosphere Watch Program

Ongoing

The presence of volatile organic compounds (VOCs), which include hydrocarbons, monoterpenes and oxygenates, in the atmosphere has become important to climate

Dietary Supplement Laboratory Quality Assurance Program (DSQAP)

Ongoing

The National Institute of Standards and Technology (NIST), in collaboration with the National Institutes of Health (NIH) Office of Dietary Supplements (ODS)

Electron Ionization Library Component of the NIST/EPA/NIH Mass Spectral Library and NIST GC Retention Index Database

Ongoing

The National Institute of Standards and Technology (NIST) has developed and maintains evaluated libraries of reference data for the identification of chemicals

Environmental Leaching of Nanoparticles from Consumer Products

Ongoing

Nanoparticle-based consumer products are becoming available in the market at an increasing rate, but the safety of nanoparticles and the environmental fate of

Environmental Metabolomics

Ongoing

The metabolomics program at NIST is a collaboration between multiple institutions located at the Hollings Marine Laboratory (HML) in Charleston, SC. This

Establishing Measurement Traceability for Gaseous Mercury Emissions Monitoring

Ongoing

As a result of the environmental impact of mercury and the neurotoxic risk associated with trophic transfer of methyl mercury to humans, the reduction of

Evaluation of Independent High-Precision Assay Procedures for a High-Purity Primary Standard Reagent

Ongoing

NIST assigns assay values for a suite of high-purity reagents using two techniques: coulometry and titrimetry. Coulometry is based on Faraday's Laws of

Expression of Stable Isotopically Labeled Proteins for Use as Internal Standards for Mass Spectrometric Quantitation of Clinical Protein Biomarkers

Ongoing

Proteins are of significant interest as potential indicators (biomarkers) of health or disease. Clinical methods employed to measure these analytes are often

Analytical chemistry

Projects/Programs

Consistency Analysis and Uncertainty in ‘omic Data

Continuing Support of Cement Manufacturing

Determinations of Boron Deposit Quality by Neutron Depth Profiling

Development of Methods for Measurement of Vitamin D and its Metabolites in Foods, Fortified Foods, and Dietary Supplements

Development of Proteomics-Based Methods for Protein Quantification

Development of Reference Measurement Procedures and Reference Materials for Creatinine

Development of Reference Methods and Reference Materials for the Determination of Cardiac Troponin I in Human Serum

Development of Reference Methods and Reference Materials for Proteins

Development of Reference Methods and Reference Materials for the Determination of Hormones in Human Serum

Development of SRM 955c Toxic Elements in Caprine Blood

Development of Standards for the World Meteorological Organization, Global Atmosphere Watch Program

Dietary Supplement Laboratory Quality Assurance Program (DSQAP)

Electron Ionization Library Component of the NIST/EPA/NIH Mass Spectral Library and NIST GC Retention Index Database

Environmental Leaching of Nanoparticles from Consumer Products

Environmental Metabolomics

Establishing Measurement Traceability for Gaseous Mercury Emissions Monitoring

Evaluation of Independent High-Precision Assay Procedures for a High-Purity Primary Standard Reagent

Expression of Stable Isotopically Labeled Proteins for Use as Internal Standards for Mass Spectrometric Quantitation of Clinical Protein Biomarkers

Far-infrared Spectroscopy of Biomolecules (Archived)

Fatty Acids in Human Serum and Plasma Quality Assurance Program (FAQAP)

Fluid Phase Nuclear Magnetic Resonance (NMR) Spectroscopy

Food Nutrition and Safety Measurements Quality Assurance Program (FNSQAP)

Fossil Fuel Standard Reference Materials

Gas Concentration Standards Supporting Atmospheric Monitoring

Health Assessment Measurements Quality Assurance Program (HAMQAP)

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