Analytical chemistry

News and Updates

A Safer Way for Police to Test Drug Evidence

September 17, 2019

Scientists have demonstrated a way for police to quickly and safely test whether a baggie or other package contains...

A woman with goggles prepares a sample near a large instrument.

How Milk Does an Animal Body Good

May 07, 2019

It has been called the world’s most perfect food, and there’s unequivocal evidence that it can fight off disease and...

Two vials, one with heroin and one with an equivalent dose of fentanyl, which is a much smaller amount.

New Protocol for Measuring Background Levels of Drugs in Crime Labs

September 25, 2018

When crime lab chemists handle evidence that contains illegal drugs, trace amounts of those drugs are inevitably...

Giant metal tubs are being opened and white vapor is puffing up into the face of one researcher who is in a protective suit with hood, gloves and eye protection. In the background, several other suited researchers discuss something.

Staying Chill, Even When Disaster Strikes

When most people prepare for a hurricane, they buy food and water. But when scientist Amanda Moors sees one of those...

Publications

A photonic pH sensor based on photothermal spectroscopy

September 12, 2019

Author(s):

Zeeshan Ahmed, Nathan J. Castro, Matthew R. Hartings

Although the determination of pH is a standard laboratory measurement, new techniques capable of measuring pH are being developed to facilitate modern...

Mass Spectrometry Fingerprints of Small-Molecule Metabolites in Biofluids. Building a Spectral Library of Recurrent Spectra for Urine Analysis

August 19, 2019

Author(s):

Yamil Simon, Ramesh Marupaka, Xinjian Yan, Yuxue Liang, Kelly H. Telu, Yuri A. Mirokhin

A large fraction of ions observed in electrospray liquid chromatography-mass spectrometry (LC- MS) experiments of biological samples remain unidentified. One...

Unusual Regularity in GC Retention of Simple Amino Acid Derivatives

August 08, 2019

Author(s):

Anzor I. Mikaia, Nino G. Todua, Zenkevich G. Igor

Background. Application of simple regularities and the general principles along with direct use of reference retention index data is a useful approach for...

Ampoules for Radioactivity Standard Reference Materials

August 06, 2019

Author(s):

Ronald Colle

Standard-sized ampoules for radioactive solution standards have been employed by the National Institute of Standards and Technology (NIST) for nearly the past...

Projects & Programs

Metabolomics Quality Assurance and Quality Control Materials (MetQual) Program

The NIST Metabolomics Quality Assurance and Quality Control Materials (MetQual) Program has been created to demonstrate and improve the comparability of...

Opioid Detection and Identification

NIST, the nation’s reference lab for chemical measurements, helps crime labs and medical first responders rapidly detect and identify opioids, particularly new...

Biomaterials for Oral Health

Our goal is to enable the development and manufacturing of biomaterials for oral health moving forward in 21st century by providing critical measurement...

Understanding the Bioaccumulation of Gadolinium-Based Contrast Agents using Advanced Measurement Capabilities

Gadolinium-Based Contrast Agents (GBCA) are intravenous drugs used in diagnostic imaging procedures to enhance the quality of magnetic resonance imaging (MRI...

Software

NIST Mass and Fragment Calculator Software

The NIST Mass and Fragment Calculator is a program written in Visual Basic which calculates the mass of an input peptide or protein sequence along with m/z...

NIST DTSA-II

NIST DTSA-II builds on the best available algorithms in the literature to simulate, quantify and plan energy dispersive x-ray analysis measurements.

JB95 Spectral fitting program

A graphical user interface program, JB95 , based on a Windows 95 © API platform has been written in the C programming language to aid in the analysis of...

Simulated Chromatographic Data

The following information is provided as an aid in the validation of mathematical models used in quantitation with chromatographic data. This data may also be...

Analytical chemistry

News and Updates

A Safer Way for Police to Test Drug Evidence

How Milk Does an Animal Body Good

New Protocol for Measuring Background Levels of Drugs in Crime Labs

Staying Chill, Even When Disaster Strikes

Publications

A photonic pH sensor based on photothermal spectroscopy

Mass Spectrometry Fingerprints of Small-Molecule Metabolites in Biofluids. Building a Spectral Library of Recurrent Spectra for Urine Analysis

Unusual Regularity in GC Retention of Simple Amino Acid Derivatives

Ampoules for Radioactivity Standard Reference Materials

Projects & Programs

Metabolomics Quality Assurance and Quality Control Materials (MetQual) Program

Opioid Detection and Identification

Biomaterials for Oral Health

Understanding the Bioaccumulation of Gadolinium-Based Contrast Agents using Advanced Measurement Capabilities

Software

NIST Mass and Fragment Calculator Software

NIST DTSA-II

JB95 Spectral fitting program

Simulated Chromatographic Data

Tools & Instruments

Continuous-wave terahertz spectrometer

TESCAN MIRA3 for automated electron microscopy

Fourier Transform Infrared Spectroscopy

Milli X-Ray Fluorescence Spectrometer