Analytical chemistry

News and Updates

A Standard for Standards

March 19, 2018

A new NIST standard ensures reliably accurate comparisons of measurements of the purity of tens of thousands of organic...

A graph with vertical lines showing the mass spectrum of fentanyl

Free Software Can Help Spot New Forms of Fentanyl and Other Illegal Drugs

March 07, 2018

Fentanyl, the synthetic drug that is driving a nationwide overdose epidemic, is not only a killer. It’s also a shape...

NIST Announces 2018 Small Business Innovation Research Funding Opportunity

February 16, 2018

The National Institute of Standards and Technology (NIST) is now accepting proposals for its 2018 Small Business...

Detecting Chemical Agents with Confidence

January 17, 2018

The Joint Chemical Agent Detector (JCAD) has become an important defense tool on battlefields and in war-torn cities...

Publications

Evaluating droplet digital PCR for the quantification of human genomic DNA: converting copies per nanoliter to nanograms nuclear DNA per microliter

February 22, 2018

Author(s):

David L. Duewer, Margaret C. Kline, Erica L. Romsos, Blaza Toman

The highly multiplexed polymerase chain reaction (PCR) assays used for forensic human identification perform best when used with an accurately determined...

Nanostructured lipid-based films for substrate-mediated applications in biotechnology

January 10, 2018

Author(s):

Minjee Kang, Mohit Tuteja, Andrea Centrone, Daniel Topgaard, Cecilia Leal

Amphiphilic in nature, lipids spontaneously self-assemble into a range of nanostructures in the presence of water. Among lipid self-assembled structures,...

Multidimensional Iterative Lineshape-Enhanced (SMILE) Reconstruction of Both Non-Uniformly Sampled and Conventional NMR Data

January 02, 2018

Author(s):

Jinfa Ying, Frank Delaglio, Dennis Torchia, Adriaan Bax

Implementation of a new algorithm, SMILE, is described for reconstruction of non-uniformly sampled two-, three- and four-dimensional NMR data, which takes...

FEASIBILITY OF USING THE NATIONAL MARINE MAMMAL TISSUE BANK FOR RETROSPECTIVE EXPLORATORY STUDIES OF PERFLUORINATED ALKYL ACIDS

December 26, 2017

Author(s):

Jennifer M. Lynch, Jared M. Ragland, Amanda J. Moors, Rebecca S. Pugh, Jessica L. Reiner

Perfluorinated alkyl acids (PFAAs) have been used for more than 50 years in materials such as stain-resistant treatments for paper and clothing, lubricants,...

Projects & Programs

Metabolomics Quality Assurance and Quality Control Materials (MetQual) Program

The NIST Metabolomics Quality Assurance and Quality Control Materials (MetQual) Program has been created to demonstrate and improve the comparability of...

Biomaterials for Oral Health

Our goal is to enable the development and manufacturing of biomaterials for oral health moving forward in 21st century by providing critical measurement...

Understanding the Bioaccumulation of Gadolinium-Based Contrast Agents using Advanced Measurement Capabilities

Gadolinium-Based Contrast Agents (GBCA) are intravenous drugs used in diagnostic imaging procedures to enhance the quality of magnetic resonance imaging (MRI...

Method Assessment for Non-Targeted Analyses (MANTA) Program

The MANTA Program is an ongoing collaboration with laboratories to increase the comparability and reproducibility of their results using non-targeted analysis...

Software

NIST Mass and Fragment Calculator Software

The NIST Mass and Fragment Calculator is a program written in Visual Basic which calculates the mass of an input peptide or protein sequence along with m/z...

NIST DTSA-II

NIST DTSA-II builds on the best available algorithms in the literature to simulate, quantify and plan energy dispersive x-ray analysis measurements.

JB95 Spectral fitting program

A graphical user interface program, JB95 , based on a Windows 95 © API platform has been written in the C programming language to aid in the analysis of...

Simulated Chromatographic Data

The following information is provided as an aid in the validation of mathematical models used in quantitation with chromatographic data. This data may also be...

Analytical chemistry

News and Updates

A Standard for Standards

Free Software Can Help Spot New Forms of Fentanyl and Other Illegal Drugs

NIST Announces 2018 Small Business Innovation Research Funding Opportunity

Detecting Chemical Agents with Confidence

Publications

Evaluating droplet digital PCR for the quantification of human genomic DNA: converting copies per nanoliter to nanograms nuclear DNA per microliter

Nanostructured lipid-based films for substrate-mediated applications in biotechnology

Multidimensional Iterative Lineshape-Enhanced (SMILE) Reconstruction of Both Non-Uniformly Sampled and Conventional NMR Data

FEASIBILITY OF USING THE NATIONAL MARINE MAMMAL TISSUE BANK FOR RETROSPECTIVE EXPLORATORY STUDIES OF PERFLUORINATED ALKYL ACIDS

Projects & Programs

Metabolomics Quality Assurance and Quality Control Materials (MetQual) Program

Biomaterials for Oral Health

Understanding the Bioaccumulation of Gadolinium-Based Contrast Agents using Advanced Measurement Capabilities

Method Assessment for Non-Targeted Analyses (MANTA) Program

Software

NIST Mass and Fragment Calculator Software

NIST DTSA-II

JB95 Spectral fitting program

Simulated Chromatographic Data

Tools & Instruments

TESCAN MIRA3 for automated electron microscopy

Fourier Transform Infrared Spectroscopy

Milli X-Ray Fluorescence Spectrometer

Environmental Scanning Electron Microscope