Analytical chemistry

News and Updates

A woman with goggles prepares a sample near a large instrument.

How Milk Does an Animal Body Good

May 07, 2019

It has been called the world’s most perfect food, and there’s unequivocal evidence that it can fight off disease and...

Two vials, one with heroin and one with an equivalent dose of fentanyl, which is a much smaller amount.

New Protocol for Measuring Background Levels of Drugs in Crime Labs

September 25, 2018

When crime lab chemists handle evidence that contains illegal drugs, trace amounts of those drugs are inevitably...

Giant metal tubs are being opened and white vapor is puffing up into the face of one researcher who is in a protective suit with hood, gloves and eye protection. In the background, several other suited researchers discuss something.

Staying Chill, Even When Disaster Strikes

When most people prepare for a hurricane, they buy food and water. But when scientist Amanda Moors sees one of those...

Data-Sharing Website May Speed Response to New Illegal Drugs

July 05, 2018

The drug overdose epidemic currently gripping the nation is so tenacious in part because it’s being driven by fentanyl...

Publications

Isotope Dilution Liquid Chromatography-Tandem Mass Spectrometry for Quantitative Amino Acid Analysis

June 03, 2019

Author(s):

David M. Bunk, Mark S. Lowenthal

The role of amino acid analysis in bioanalysis has changed from a qualitative to a quantitative technique. With the discovery of both electrospray ionization...

Health Assessment Measurements Quality Assurance Program: Exercise 2 Final Report

May 21, 2019

Author(s):

Charles A. Barber, Jeanice M. Brown Thomas, Carolyn Q. Burdette, Johanna Camara, Stephen E. Long, Melissa M. Phillips, Benjamin J. Place, Catherine A. Rimmer, Laura J. Wood, Lee L. Yu

The NIST Health Assessment Measurements Quality Assurance Program (HAMQAP) was launched in collaboration with the National Institutes of Health (NIH) Office of...

Certification of Standard Reference Material® 2193b Calcium Carbonate [used as saturated Ca(OH)2 solution]

May 16, 2019

Author(s):

Regina A. Easley, Jason F. Waters, William F. Guthrie

Practical Guides for X-Ray Photoelectron Spectroscopy: First Steps in Planning, Conducting, and Reporting XPS Measurements

May 15, 2019

Author(s):

Cedric J. Powell, Donald R. Baer, Kateryna Artyushkova, Christopher R. Brundle, James E. Castle, Mark Engelhard, Karen Gaskell, John Grant, Richard Haasch, Matthew Linford, Peter Sherwood, Vincent Smentkowski, Alexander Shard

Over the past three decades, the use of x-ray photoelectron spectroscopy (XPS) in research and applications has grown to make XPS the most popular method of...

Projects & Programs

Metabolomics Quality Assurance and Quality Control Materials (MetQual) Program

The NIST Metabolomics Quality Assurance and Quality Control Materials (MetQual) Program has been created to demonstrate and improve the comparability of...

Opioid Detection and Identification

NIST, the nation’s reference lab for chemical measurements, helps crime labs and medical first responders rapidly detect and identify opioids, particularly new...

Biomaterials for Oral Health

Our goal is to enable the development and manufacturing of biomaterials for oral health moving forward in 21st century by providing critical measurement...

Understanding the Bioaccumulation of Gadolinium-Based Contrast Agents using Advanced Measurement Capabilities

Gadolinium-Based Contrast Agents (GBCA) are intravenous drugs used in diagnostic imaging procedures to enhance the quality of magnetic resonance imaging (MRI...

Software

NIST Mass and Fragment Calculator Software

The NIST Mass and Fragment Calculator is a program written in Visual Basic which calculates the mass of an input peptide or protein sequence along with m/z...

NIST DTSA-II

NIST DTSA-II builds on the best available algorithms in the literature to simulate, quantify and plan energy dispersive x-ray analysis measurements.

JB95 Spectral fitting program

A graphical user interface program, JB95 , based on a Windows 95 © API platform has been written in the C programming language to aid in the analysis of...

Simulated Chromatographic Data

The following information is provided as an aid in the validation of mathematical models used in quantitation with chromatographic data. This data may also be...

Analytical chemistry

News and Updates

How Milk Does an Animal Body Good

New Protocol for Measuring Background Levels of Drugs in Crime Labs

Staying Chill, Even When Disaster Strikes

Data-Sharing Website May Speed Response to New Illegal Drugs

Publications

Isotope Dilution Liquid Chromatography-Tandem Mass Spectrometry for Quantitative Amino Acid Analysis

Health Assessment Measurements Quality Assurance Program: Exercise 2 Final Report

Certification of Standard Reference Material® 2193b Calcium Carbonate [used as saturated Ca(OH)2 solution]

Practical Guides for X-Ray Photoelectron Spectroscopy: First Steps in Planning, Conducting, and Reporting XPS Measurements

Projects & Programs

Metabolomics Quality Assurance and Quality Control Materials (MetQual) Program

Opioid Detection and Identification

Biomaterials for Oral Health

Understanding the Bioaccumulation of Gadolinium-Based Contrast Agents using Advanced Measurement Capabilities

Software

NIST Mass and Fragment Calculator Software

NIST DTSA-II

JB95 Spectral fitting program

Simulated Chromatographic Data

Tools & Instruments

Continuous-wave terahertz spectrometer

TESCAN MIRA3 for automated electron microscopy

Fourier Transform Infrared Spectroscopy

Milli X-Ray Fluorescence Spectrometer