Analytical chemistry

News and Updates

Two vials, one with heroin and one with an equivalent dose of fentanyl, which is a much smaller amount.

New Protocol for Measuring Background Levels of Drugs in Crime Labs

September 25, 2018

When crime lab chemists handle evidence that contains illegal drugs, trace amounts of those drugs are inevitably...

Giant metal tubs are being opened and white vapor is puffing up into the face of one researcher who is in a protective suit with hood, gloves and eye protection. In the background, several other suited researchers discuss something.

Staying Chill, Even When Disaster Strikes

When most people prepare for a hurricane, they buy food and water. But when scientist Amanda Moors sees one of those...

Data-Sharing Website May Speed Response to New Illegal Drugs

July 05, 2018

The drug overdose epidemic currently gripping the nation is so tenacious in part because it’s being driven by fentanyl...

Recent Patent Activity within ACMD

June 07, 2018

A provisional patent by Tom Bruno and Kim Urness of the Applied Chemicals and Materials Division on Inductive Flash...

Publications

SURVEY OF PEPTIDE QUANTIFICATION METHODS AND THEIR REPRODUCIBILITY COMPARISON: A CASE STUDY USING OXYTOCIN

March 20, 2019

Author(s):

Chensheng Li, Sitaram Bhavaraju, Jeremy Melanson, Andreas Blomgren, Torgny Rundlof, Eric L. Kilpatrick, Timothy Rudd, Yves Aubin, Kevin Grant, Edward Saravolac, Tursun Kerim, William Sherman, Yukari Nakagawa, Sergi Pavon, Tim Weel, Arunima Pola, Dinesh Chalasani, Stephen Walfish, Fouad Atouf

USPs peptide reference standards content is typically determined using an HPLC assay against an external standard for which the purity was determined by...

Polycyclic Aromatic Hydrocarbons (PAHs) in Marine Mammal Blubber: Results from an Interlaboratory Study

March 20, 2019

Author(s):

Kevin M. Huncik, John R. Kucklick, Jared M. Ragland

To support NOAAs Marine Mammal Health and Stranding program, NIST Charleston was requested to investigate the feasibility of measuring polycyclic...

interlab: A Python module for analyzing interlaboratory comparison data

March 15, 2019

Author(s):

David A. Sheen

interlab was developed as a software tool to perform consensus analysis on spectral data from interlaboratory studies. It is designed to estimate the spread in...

Per- and polyfluoroalkyl substances (PFAS) in plasma of the West Indian manatee (Trichechus manatus)

March 01, 2019

Author(s):

Kady Palmer, Jacqueline T. Bangma, Jessica L. Reiner, Robert Bonde, Jeffery Korte, Ashley S. Boggs-Russell, John Bowden

Per- and polyfluoroalkyl substances (PFAS) are ubiquitous, synthetic anthropogenic chemicals known to infiltrate and persist in biological systems as a result...

Projects & Programs

Metabolomics Quality Assurance and Quality Control Materials (MetQual) Program

The NIST Metabolomics Quality Assurance and Quality Control Materials (MetQual) Program has been created to demonstrate and improve the comparability of...

Opioid Detection and Identification

NIST, the nation’s reference lab for chemical measurements, helps crime labs and medical first responders rapidly detect and identify opioids, particularly new...

Biomaterials for Oral Health

Our goal is to enable the development and manufacturing of biomaterials for oral health moving forward in 21st century by providing critical measurement...

Understanding the Bioaccumulation of Gadolinium-Based Contrast Agents using Advanced Measurement Capabilities

Gadolinium-Based Contrast Agents (GBCA) are intravenous drugs used in diagnostic imaging procedures to enhance the quality of magnetic resonance imaging (MRI...

Software

NIST Mass and Fragment Calculator Software

The NIST Mass and Fragment Calculator is a program written in Visual Basic which calculates the mass of an input peptide or protein sequence along with m/z...

NIST DTSA-II

NIST DTSA-II builds on the best available algorithms in the literature to simulate, quantify and plan energy dispersive x-ray analysis measurements.

JB95 Spectral fitting program

A graphical user interface program, JB95 , based on a Windows 95 © API platform has been written in the C programming language to aid in the analysis of...

Simulated Chromatographic Data

The following information is provided as an aid in the validation of mathematical models used in quantitation with chromatographic data. This data may also be...

Analytical chemistry

News and Updates

New Protocol for Measuring Background Levels of Drugs in Crime Labs

Staying Chill, Even When Disaster Strikes

Data-Sharing Website May Speed Response to New Illegal Drugs

Recent Patent Activity within ACMD

Publications

SURVEY OF PEPTIDE QUANTIFICATION METHODS AND THEIR REPRODUCIBILITY COMPARISON: A CASE STUDY USING OXYTOCIN

Polycyclic Aromatic Hydrocarbons (PAHs) in Marine Mammal Blubber: Results from an Interlaboratory Study

interlab: A Python module for analyzing interlaboratory comparison data

Per- and polyfluoroalkyl substances (PFAS) in plasma of the West Indian manatee (Trichechus manatus)

Projects & Programs

Metabolomics Quality Assurance and Quality Control Materials (MetQual) Program

Opioid Detection and Identification

Biomaterials for Oral Health

Understanding the Bioaccumulation of Gadolinium-Based Contrast Agents using Advanced Measurement Capabilities

Software

NIST Mass and Fragment Calculator Software

NIST DTSA-II

JB95 Spectral fitting program

Simulated Chromatographic Data

Tools & Instruments

Continuous-wave terahertz spectrometer

TESCAN MIRA3 for automated electron microscopy

Fourier Transform Infrared Spectroscopy

Milli X-Ray Fluorescence Spectrometer