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Search Publications by

Vincent A. Hackley (Fed)

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Displaying 26 - 50 of 147

Surface Modification of Cisplatin-Complexed Gold Nanoparticles and Its Influence on Colloidal Stability, Drug Loading, and Drug Release

November 10, 2017
Jiaojie Tan, Tae Joon Cho, De-Hao Tsai, Jingyu Liu, John M. Pettibone, Rian You, Michael R. Zachariah, Vincent A. Hackley
Cisplatin-complexed gold nanoparticles (PtII-AuNP) provide a promising strategy for chemo- radiation based anticancer drugs. Effective design of such platforms necessitates reliable assessment of surface engineering on a quantitative basis, and its

Quantitative Analysis of Oxidation State in Cerium Oxide Nanomaterials

May 14, 2017
Christopher Sims, Russell Maier, Aaron Johnston-Peck, Justin Gorham, Vincent A. Hackley, Bryant C. Nelson
Cerium oxide nanoparticles (nanoceria) are receiving increased attention from the research community due to the large number and wide range of their current and potential applications. The attractiveness of nanoceria for these various applications is

Reference nanomaterials to improve the reliability of nanoscale measurements

March 1, 2017
Gert Roebben, Vincent A. Hackley, Hendrik Emons
Reference materials are essential tools to assure the quality of measurement results, from R&D labs to production facilities. They help increase the reliability of measurements, as laboratories can use reference materials to verify, for themselves, and

Photochemical transformations of thiolated polyethylene glycol coatings on gold nanoparticles

August 16, 2016
Stacey M. Louie, Justin M. Gorham, Eric A. McGivney, Jingyu Liu, Kelvin B. Gregory, Vincent A. Hackley
Photochemical reactions can result in significant transformations of manufactured nanomaterials in sunlit environments. While transformations of inorganic nanoparticles (NPs) have been investigated extensively, much less attention has been focused on the

Electrospray Differential Mobility Hyphenated with Single Particle Mass Spectrometry for Characterization of Nanoparticles and their Aggregates

August 1, 2016
Jiaojie Tan, Jingyu Liu, Mingdong M. Li, Hind El Hadri, Vincent A. Hackley, Michael R. Zachariah
The hyphenation of electrospray-differential mobility analysis with single particle-inductively coupled plasma mass spectrometry (ES-DMA-spICP-MS) was demonstrated with the capacity for real- time size, mass and concentration measurement of nanoparticles

Orthogonal Analysis of Functional Gold Nanoparticles for Biomedical Applications

September 11, 2015
De-Hao D. Tsai, Yi-Fu Lu, Frank W. DelRio, Tae Joon Cho, Suvajyoti S. Guha, Michael R. Zachariah, Fan Zhang, Andrew J. Allen, Vincent A. Hackley
We report a comprehensive strategy based on implementation of orthogonal measurement techniques to provide critical and verifiable material characteristics for functionalized gold nanoparticles (AuNPs) used in biomedical applications. Thiolated

Fractionation and characterization of high aspect ratio gold nanorods using asymmetric-flow field flow fractionation and single particle inductively coupled plasma mass spectrometry

July 14, 2015
Thao M. Nguyen, Jingyu Liu, Vincent A. Hackley
Development of methods for the in situ fractionation and characterization of high aspect ratio (AR) gold nanorods (GNRs) is a rapidly growing area of interest within the nanotechnology field, particularly with respect to nanomanufacturing and biomedical

Preparation of silver nanoparticle loaded cotton threads to facilitate measurement development for textile applications

January 26, 2015
Justin M. Gorham, Karen E. Murphy, Jingyu Liu, Dimitri Tselenchuk, Gheorghe NMN Stan, Thao M. Nguyen, Richard D. Holbrook, Michael R. Winchester, Robert F. Cook, Robert MacCuspie, Vincent A. Hackley
FOREWORD This NIST special publication (SP) is one in a series of NIST SPs that address research needs articulated in the National Nanotechnology Initiative (NNI) Environmental, Health, and Safety Research Strategy published in 2011 [1]. This Strategy

Accurate determination of the size distribution for polydisperse, cationic metallic nanomaterials by asymmetric-flow field flow fractionation

November 13, 2014
Julien C. Gigault, Thao M. Nguyen, John M. Pettibone, Vincent A. Hackley
In this work we have developed and validated a methodology for determining the size distribution in polydisperse cationic nanoparticle (NP) samples using asymmetric-flow field flow fractionation (A4F), where known compositional influence of previously used

Potential artifacts and misinterpretations when evaluating the ecotoxicological effects of nanomaterials

June 16, 2014
Elijah J. Petersen, Theodore Henry, Jian Zhao, Robert MacCuspie, Teresa L. Kirschling, Vincent A. Hackley, Baoshan Xing, Jason White
Engineered nanomaterials (ENMs) have significant commercial potential in a broad range of industries for consumer products as a result of their novel properties. However, these same properties may cause unexpected risks once ENMs are released into the

Use of Single Particle Inductively Coupled Plasma Mass Spectrometry to Characterize a New Silver Nanoparticle Reference Material

June 11, 2014
Karen E. Murphy, Jingyu Liu, William F. Guthrie, Justin M. Gorham, John E. Bonevich, Andrew J. Allen, Michael R. Winchester, Vincent A. Hackley, Robert MacCuspie
In this study we use inductively coupled plasma mass spectrometry operated in single particle mode (spICP-MS) to simultaneously characterize the size distribution and dissolved silver fraction of a new silver nanoparticle (AgNP) candidate reference

Potential artifacts when evaluating the ecotoxicological effects of nanomaterials

March 28, 2014
Elijah J. Petersen, Marina Dobrovolskaia, Theodore B. Henry, Jian Zhao, Robert I. MacCuspie, Teresa L. Kirschling, Baoshan Xing, Vincent A. Hackley, Jason White
Engineered nanomaterials (ENMs) have a significant commercial potential for ENM-enable products as a result of novel or enhanced properties. However, the unique behaviors of ENMs may also cause artifacts, spurious results, effects, or findings, when

Highly Stable Positively Charged Dendron-Encapsulated Gold Nanoparticles

March 13, 2014
Tae Joon Cho, Robert I. MacCuspie, Julien C. Gigault, Justin M. Gorham, John T. Elliott, Vincent A. Hackley
We report the development of a novel cationic dendron (TAG1-PCD) and a positively charged gold nanoparticle-dendron conjugate (PCD-AuNP). TAG1-PCD was designed by considering the reactivity, hydrophilicity, and cationic nature that is required to yield a

Controlled Formation and Characterization of Dithiothreitol-Conjugated Gold Nanoparticle Clusters

March 5, 2014
De-Hao D. Tsai, Tae Joon Cho, Frank W. DelRio, Justin Gorham, Jiwen Zheng, Jiaojie Tan, Michael R. Zachariah, Vincent A. Hackley
We report a systematic study of the controlled formation of discrete-size gold nanoparticle clusters (GNCs) by interaction with the reducing agent dithiothreitol (DTT). Asymmetric-flow field flow fractionation and electrospray differential mobility