Skip to main content
U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Search Publications

NIST Authors in Bold

Displaying 26 - 50 of 1664

Hierarchical Cellulose Nanocrystal Blends for Bioinspired Damage Tolerant Photonic Films

May 4, 2018
Bharath NMN Natarajan, Ajay Krishnamurthy, Caglar Dogu Emiroglu, Amanda L. Forster, E. J. Foster, Christoph Weder, Douglas M. Fox, Jan Obrzut, Jeffrey W. Gilman
Attempts to emulate strong and tough natural composites using wood cellulose nanocrystals (CNCs) fall short in mechanical performance due to the low shear transfer ability of CNC interfaces in their helicoidal ensembles. This shortcoming is ascribed to the

Cholesterol Functionalized Aliphatic N-Substituted 8 Membered Cyclic Carbonate

April 10, 2018
Vivek M. Prabhu, Shrinivas Venkataraman, Kenneth Mineart, James Hedrick, Yi Yan Yang
Straightforward synthesis of cholesterol functionalized aliphatic N-substituted 8 membered cyclic carbonate monomer is reported. Well-defined PEGylated diblock copolymers were readily accessed via organo catalytic ring opening polymerization. These block

The Evolution of Polystyrene as a Cell Culture Material: A Brief History

April 10, 2018
Max J. Lerman, Josephine Lembong, Shinichiro Muramoto, John G. Gillen, John P. Fisher
Polystyrene (PS) has brought in vitro cell culture from its humble beginnings to the modern era, propelling dozens of research fields along the way. This review discusses the development of the material, fabrication, and treatment approaches to create the

The NISTmAb Reference Material 8671 Value Assignment, Homogeneity, and Stability

March 1, 2018
John E. Schiel, Abigail Turner, Catherine A. Mouchahoir, Katharina S. Yandrofski, Srivalli Telikepalli, Jason King, Paul C. DeRose, Dean C. Ripple, Karen W. Phinney
The NISTmAb Reference Material (RM) 8671 is intended to be the common industry standard monoclonal antibody for pre-competitive research in harmonizing current state-of-the-art technology and designing next generation characterization technologies for

Acid-induced and pH-controlled Reversible Switching of Broad-Spectrum Antibacterial Activity

February 13, 2018
Yin Y. Nelson, Vytautas Reipa, Xiaohong Wang, Kenneth Mineart, Vivek M. Prabhu, Nancy J. Lin, Jirun Sun
Bacterial resistance to antimicrobials is threatening millions of human lives due to indiscriminate overuse and environmental build-up of antibiotics. We present the smart regulation of antibacterial activity in biologically relevant conditions to reduce

Development of Orthogonal NISTmAb Size Heterogeneity Control Methods

February 10, 2018
Abigail Turner, Katharina S. Yandrofski, Srivalli Telikepalli, Nathanael A. Heckert, James J. Filliben, Dean C. Ripple, John E. Schiel
The NISTmAb is an innovative monoclonal antibody reference material from the National Institute of Standards and Technology; it is a class-representative IgG1κ intended to serve as a pre-competitive platform for harmonization and technology development in

NIST Micronutrients Measurement Quality Assurance Program Winter and Summer 2017 Comparability Studies: Results for Round Robins LXXXI and LXXXII Fat-Soluble Vitamins and Carotenoids in Human Serum

January 10, 2018
Jeanice M. Brown Thomas, David L. Duewer
The National Institute of Standards and Technology coordinates the Micronutrients Measurement Quality Assurance Program (MMQAP) for laboratories that measure fat-soluble vitamins and carotenoids in human serum and plasma. This report describes the design

Modeling, Validation and Verification of Three-Dimensional Cell-Scaffold Contacts from Terabyte- sized Images

December 1, 2017
Peter Bajcsy, Sowon Joy Yoon, Stephen Florczyk, Nathan Hotaling, Mylene H. Simon, Piotr Szczypinski, Nicholas J. Schaub, Carl G. Simon Jr., Mary C. Brady, Ram D. Sriram
Background: Cell-scaffold contact measurements are derived from pairs of co-registered volumetric fluorescent confocal laser scanning microscopy (CLSM) images (z-stacks) of stained cells and spun coat, large microfiber, and medium microfiber scaffolds. Our

Indentation mapping revealed poroelastic, but not viscoelastic,properties spanning native zonal articular cartilage

November 8, 2017
Joseph Wahlquist, Frank W. DelRio, Mark Randolph, Aaron Aziz, Chelsea Heveran, Stephanie Bryant, Corey P. Neu, Virginia L. Ferguson
Osteoarthrosis is a debilitating disease affecting millions, yet engineering materials for cartilage regeneration has proven difficult because of the complex microstructure of this tissue. Articular cartilage, like many biological tissues, produces a time

Buckling Instabilities in Polymer Brush Surfaces via Postpolymerization Modification

October 30, 2017
Wei Guo, Cassandra M. Reese, Li Xiong, Phillip K. Logan, Brittany J. Thompson, Christopher M. Stafford, Anton Ievlev, Bradley S. Lokitz, Olga S. Ovchinnikova, Derek L. Patton
We report a simple route to engineer ultrathin polymer brush surfaces with wrinkled and creased morphologies using postpolymerization modification (PPM), where the length scale of the buckled features can be tuned using PPM reaction time and sequence. We

Hydrogels with Reversible Mechanics to Probe Dynamic Cell Microenvironments

October 4, 2017
Adrianne Rosales, Sebastain Vega, Frank W. DelRio, Jason Burdick, Kristi S. Anseth
The relationship between ECM mechanics and cell behavior is dynamic, as cells remodel and respond to changes in their local environment. Most in vitro substrates are static and supraphysiologically stiff; thus, platforms with dynamic and reversible

Formation of a crack-free, hybrid skin layer with tunable surface topography and improved gas permeation selectivity on elastomers using gel-liquid infiltration polymerization

September 11, 2017
Justin M. Gorham, Jason P. Killgore, Maryam Omidvar, Haiqing Lin, Frank W. DelRio, Lewis M. Cox, Zheng Zhang
Liquid-liquid interfacial polymerization (ll-IP) is conventionally used for manufacturing bulk polymers like nylon, as well as forming barrier layers for reverse osmosis membranes. In this work, we explore the use of gel-liquid infiltration polymerization

3D Cellular Morphotyping of Cell Niches

August 31, 2017
Stephen J. Florczyk, Mylene H. Simon, Derek Juba, Patrick S. Pine, Sumona Sarkar, Desu Chen, Paula J. Baker, Subhadip Bodhak, Antonio Cardone, Mary C. Brady, Peter Bajcsy, Carl G. Simon Jr.
Three-dimensional (3D) cellular morphotyping is introduced for assessing and comparing the niches provided by biomaterial scaffolds. Many scaffold systems have been advanced to provide synthetic cell niches for tissue engineering and drug screening

Moisture Uptake Characterization in Nanocellulose Using Microwave Cavity

August 18, 2017
Caglar Emiroglu, Bharath N. Natarajan, Jeffrey W. Gilman, James A. Liddle, Jan Obrzut
Cellulose nanocrystal films with different helical modulation lengths are characterized. Films are obtained by tuning the rate of evaporation and surface functionalization. Dielectric constant measurements are performed and the water confinement is

Surface interaction parameter measurement of solvated polymers via model end-tethered chains

August 11, 2017
Richard J. Sheridan, Sara V. Orski, Ronald L. Jones, Sushil K. Satija, Kathryn L. Beers
We present a method for the direct measurement of the relative energy of interaction between a solvated polymer and a solid interface. By tethering linear chains covalently to the surface, we ensured the idealized and constant configuration of polymer

Raman Identification of Multiple Melting Peaks of Polyethylene

August 1, 2017
Ying Jin, Anthony P. Kotula, Chad R. Snyder, Angela R. Hight Walker, Kalman D. Migler, Young J. Lee
Multiple melting peaks of high-density polyethylene produced by complex thermal pre-treatment are investigated with variable temperature Raman spectroscopy and differential scanning calorimetry (DSC). We examine the origin of the observed multiple melting

Fast-Responding Bio-Based Shape Memory Thermoplastic Polyurethanes

July 14, 2017
Zoran S. Petrovic, Jelena Milic, Fan Zhang, Jan Ilavsky
Fast response shape-memory polyurethanes were prepared from bio-based polyols, diphenyl methane diisocyanate and butane diol. The bio-based polyester polyols were synthesized from 9-hydroxynonanoic acid, a product obtained by ozonolysis of fatty acids
Displaying 26 - 50 of 1664