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Displaying 26 - 50 of 139

Identification of the Veterinary Sedative Medetomidine in Combination with Opioids and Xylazine in Maryland

March 26, 2023

Author(s)

Edward Sisco, Meghan Appley

Public health, public safety, and forensic science personnel continue to face the emergence of new compounds into the drug market. While focus is often put on the detection of new analogs of known illicit drugs, monitoring the changes in cutting agents and

Targeted fentanyl screening utilizing electrochemical surface-enhanced Raman spectroscopy (EC-SERS) applied to authentic seized drug casework samples

March 21, 2023

Author(s)

Colby Ott, Amber Burns, Edward Sisco, Luis Eduardo Arroyo

Effective and rapid screening methods for seized drug analysis are crucial to ensure the safety of first responders and laboratory personnel, while reducing overall analysis time and improving reliability. The drug landscape has been overwhelmed by

An Analytical Platform for Near Real-Time Drug Landscape Monitoring using Paraphernalia Residues

March 13, 2023

Author(s)

Meghan Appley, Liz Robinson, Allison Thomson, Erin Russell, Edward Sisco

Deaths attributed to drug overdoses are constantly on the rise, but drug trends are frequently changing and often differ across geographical regions. Current analytical techniques are limited in their abilities to rapidly identify drugs that would inform

Accurate THC Determinations in Seized Cannabis Samples for Forensic Laboratories

February 28, 2023

Author(s)

Walter Brent Wilson

Development & Validation of A Rapid GC-MS Method for Seized Drug Screening

February 15, 2023

Author(s)

Madeline Bloom, Edward Sisco, Ira Lurie

Controlled substances are one of the most frequently analyzed types of evidence in forensic laboratories. An increase in frequency of seizures in recent years has necessitated a need for rapid screening techniques to decrease case backlogs and expedite

Field-Deployable Devices

January 1, 2023

Author(s)

Thomas P. Forbes, Raychelle Burks

Reductions in instrument size, weight, and power continue to facilitate the development and application of field-deployable devices for investigative purposes. Portable analytical instrumentation supporting the rapid and reliable identification of two

Cannabis Laboratory Quality Assurance Program: Exercise 2 Moisture Final Report

November 29, 2022

Author(s)

Chuck Barber, Colleen E. Bryan Sallee, Carolyn Burdette, Shaun Kotoski, Melissa M. Phillips, Walter Brent Wilson, Laura Wood

In 2020, NIST launched Cannabis Laboratory Quality Assurance Program (CannaQAP) to improve the comparability of the analytical measurements of cannabis and cannabis-derived products in forensic and cannabis (hemp and marijuana) testing laboratories

Spectral Trends in GC-EI-MS Data Obtained from the SWGDRUG Library and Literature: A Potential Resource for Identification of Unknown Compounds

October 24, 2022

Author(s)

William Feeney, Arun Moorthy, Edward Sisco

Rapid identification of new or emerging psychoactive substances remains a critical challenge in drug chemistry laboratories. Current analytical protocols are well designed for confirmation of known substances yet present struggles when potentially new

Rapid Emerging Drug Deployment Characterization Results: P2AP (RP0003)

October 1, 2022

Author(s)

Edward Sisco, Aaron Urbas

Qualitative Analysis of Real Drug Evidence using DART-MS and the Inverted Library Search Algorithm

August 25, 2022

Author(s)

Edward Sisco, Meghan Appley, Stephen Tennyson, Arun Moorthy

Chromatographic-less mass spectrometry techniques like direct analysis in real time mass spectrometry (DART-MS) are steadily being employed as seized drug screening tools. However, these newer analytical platforms require new computational methods to best

Updates to the Inverted Library Search Algorithm for Mixture Analysis

June 8, 2022

Author(s)

Arun Moorthy, Stephen Tennyson, Edward Sisco

A Template for the Validation of DART-MS for Qualitative Seized Drugs Analysis

March 10, 2022

Author(s)

Edward Sisco, Amber Burns, Elizabeth Schneider, Laurel Bobka, Ikenna Ikpeama

Direct analysis in real time mass spectrometry (DART-MS) is an increasingly employed tool for a wide range of forensic applications including seized drug analysis. A significant body of research surrounds DART-MS for the analysis of seized drugs and how it

Development of an Open-Source Direct Analysis in Real Time Mass Spectrometry (DART-MS) Search Software and Library Building Tool for the Analysis of Complex Drug Mixtures

March 1, 2022

Author(s)

Edward Sisco, Arun Moorthy

Rapid Emerging Drug Deployment Characterization Results: N-Methyl-N-Isopropyltryptamine fumarate - 2

February 28, 2022

Author(s)

Edward Sisco, Aaron Urbas

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