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Displaying 2126 - 2150 of 2289

Stacking Faults Assist Lithium-Ion Conduction in a Halide-Based Superionic Conductor

April 6, 2022
Author(s)
Elias Sebti, Hayden Evans, Hengning Chen, Peter Richardson, Kelly White, Raynald Giovine, Krishna P. Koirala, Yaobin Xu, Eliovardo Gonzalez-Correa, Chongmin Wang, Craig Brown, Anthony Cheetham, Pieremanuele Canepa, Raphaele Clement
… with exceptional compatibility against high-voltage oxide electrodes, tunable ionic conductivities, and facile …

Principal Component Analysis for Automated Classification of 2D Spectra and Interferograms of Protein Therapeutics: Influence of Noise, Reconstruction Details, and Data Preparation

July 22, 2020
Author(s)
Robert Brinson, Wade Elliott, Luke Arbogast, David Sheen, John Giddens, John Marino, Frank Delaglio
Protein therapeutics must retain their proper three-dimensional fold without forming aggregates for safe and effective use in the clinic. Therefore, the ability to monitor protein higher order structure (HOS) can be valuable throughout the lifecycle of a

Development of an LC-MS/MS peptide mapping protocol for the NISTmAb

March 1, 2018
Author(s)
Catherine A. Mouchahoir, John E. Schiel
Peptide mapping is a component of the analytical toolbox used within the biopharmaceutical industry to aid in the identity confirmation of a protein therapeutic and to monitor degradative events such as oxidation or deamidation. These methods offer the

Biophysical Characterization of Functionalized Titania Nanoparticles and Their Application in Dental Adhesives

February 2, 2017
Author(s)
Jirun Sun, Elijah Petersen, Stephanie S. Watson, Christopher Sims, Alexander Kassman, Stanislav Frukhtbeyn, Drago Skrtic, Meryem T. Ok, Deborah Jacobs, Qiang Ye, Bryant C. Nelson
It is demonstrated that carboxylic acid-functionalized titanium dioxide (TiO2) NPs produce significantly higher levels of reactive oxygen species (ROS) after visible light irradiation (400-800 nm, 1600 mW/cm2) in comparison to nonfunctionalized TiO2 NPs

LipidPioneer: Comprehensive User-Generated Exact Mass Templates for Lipidomics

January 10, 2017
Author(s)
Candice Z. Ulmer, John Bowden, Jared M. Ragland, Timothy J. Garrett, Jeremy P. Koelmel
Lipidomics, the comprehensive measurement of lipid species in a biological system, has promising potential in biomarker discovery and elucidating disease etiology. Advances in separation, mass spectrometric techniques, and applications to novel substrates

Applicability of post-ionization theory to laser-assisted field evaporation of magnetite

December 18, 2014
Author(s)
Ann C. Chiaramonti Debay, D. K. Schreiber, Lyle M. Gordon, Karen Kruska
Analysis of the mean Fe ion charge state from laser-assisted field evaporation of magnetite (Fe3O4) reveals unexpected trends as a function of laser pulse energy that break from conventional post-ionization theory for metals. For Fe ions evaporated from

Atomic Scale Defects Associated with the Negative Bias Temperature Instability

January 1, 2014
Author(s)
Jason P. Campbell, P. M. Lenahan
We utilize magnetic resonance measurements to identify the fundamental atomic-scale defect structures involved in the negative bias temperature instability. In gate stacks composed of pure silicon dioxide, we find a degradation mechanism directly involving

Stable isotope-labeling of DNA repair proteins, and their purification and characterization

July 1, 2011
Author(s)
M Miral Dizdar, Pawel Jaruga, Prasad T. Reddy, Bryant C. Nelson, Mark S. Lowenthal
Reduced DNA repair capacity is associated with increased risk for a variety of disease processes including carcinogenesis. Thus, DNA repair proteins have the potential to be used as important predictive, prognostic and therapeutic biomarkers in cancer and
Displaying 2126 - 2150 of 2289
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