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Displaying 1 - 8 of 8

Crystal Structure of the Escherichia Coli CobW Protein Suggests a GTP-Dependent Regulatory Function in the Cobalamin Synthesis Pathway

October 12, 2021
Author(s)
P P. Khil, R D. Camerini-Otero, A Teplyakov, G Obmolova, A J. Howard, G L. Gilliland
… specificity of CobW towards guanine. Specific binding of GTP by CobW was established in a series of experiments using … label trinitrophenyl (TNP) attached to the ribose of GTP. While the crystal structure suggests the molecular function of CobW as a GTP-dependent regulator, the biological role of the protein …

Crystal Structure of the YchF Protein Reveals Binding Sites for GTP and Nucleic Acid

July 1, 2003
Author(s)
A Teplyakov, G Obmolova, S Y. Chu, J Toedt, E Eisenstein, A J. Howard, G L. Gilliland
… cleft between the domains. The structure of the putative GTP-binding site is consistent with the postulated guanine … ability of YchF to bind a double-stranded nucleic acid and GTP. Taken together with other experimental data and genomic … be part of a nucleoprotein complex and may function as a GTP-dependent translation factor. …

Combinatorial Analysis of Diagonal, Box and Greater-Than Polynomials as Packing Functions

November 1, 2015
Author(s)
Pepe Torres Jimenez, Nelson Rangel-Valdez, Raghu N. Kacker, James F. Lawrence
… discuss a bijection, called greater-than polynomials (or GTP), between restricted m- dimensional vectors over N m and N. Also, we discuss direct and inverse methods for DP, GTP and BP of any dimension m. These methods are compared in … N. Finally, we present an interesting relationship between GTP, DP and a special case of Diophantine equations. …

Conformational Changes Associated With Receptor-Stimulated Guanine Nucleotide Exchange in a Heterotrimeric G-Protein a-Subunit: NMR Analysis of the GTPgS-Bound States

March 17, 2006
Author(s)
K D. Ridge, N G. Abdulaev, Xi-Cheng Zhang, T Ngo, D M. Brabazon, John P. Marino
… triggered guanine nucleotide exchange and release of GTP?S/Mg2+-bound ChiT. An HSQC spectrum of activated GTP?S/Mg2+-bound ChiT reveals 1HN, 15N chemical shift changes … AlF4-/Mg2+-bound state. Spectral line-widths observed for GTP?S/Mg2+-bound 15N-ChiT, however, indicate that it is more …

Evidence for Structural Changes in Carboxyl-Terminal Peptides of Transducin Alpha-Subunit Upon Binding a Soluble Mimic of Light-Activated Rhodopsin

January 21, 2003
Author(s)
D M. Brabazon, N G. Abdulaev, John Marino, K D. Ridge
… peptide corresponding to the carboxyl-terminus of Gta (GtP), as well as a high-affinity peptide analog, HAP1, binds … that has been previously reported for the interaction of GtP with the light-activated signaling state, metarhodopsin … evidence for structuring of the amino terminus of either GtP or HAP1when bound to HPTRX/CDEF, nor do the spectra show …
Displaying 1 - 8 of 8
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