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Physics

Biological Physics

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Displaying 326 - 350 of 378

Shell and ligand-dependent blinking of CdSe-based core/shell nanocrystals

July 7, 2010
Author(s)
Bonghwan Chon, Sung Jun Lim, Wonjung Kim, Hyeong G. Kang, Taiha Joo, Jeeseong C. Hwang, Seung Koo Shin
Blinking of zinc blende CdSe-based core/shell nanocrystals is studied as a function of shell materials and surface ligands. CdSe/ZnS, CdSe/ZnSe/ZnS and CdSe/CdS/ZnS core/shell nanocrystals are prepared by colloidal synthesis and six monolayers of larger

Global analysis of Forster resonance energy transfer in live cells measured by fluorescence lifetime imaging microscopy exploiting the rise time of acceptor fluorescence

June 16, 2010
Author(s)
Katharine M. Mullen, Sergey Laptenok, Jan Willem , Antonie Visser, Ivo van Stokkum
A methodology is described for the detection of F rster Resonance Energy Transfer (FRET) in live cells by monitoring the rise time of the acceptor fluorescence using fluorescence lifetime imaging microscopy (FLIM). An advantage of this method is that only

Shell-dependent Blinking of CdSe-Based Core/Shell Nanocrystals

May 10, 2010
Author(s)
Seung Koo Shin, Bonghwan Chon, Sung Jun Lim, Wonjung Kim, Hyeong G. Kang, Taiha Joo, Jeeseong C. Hwang
Blinking of zinc-blende CdSe-based core/shell nanocrystals are studied as a function of shell materials. CdSe/ZnS, CdSe/ZnSe/ZnS, and CdSe/CdS/ZnS core/shell nanocrystals are prepared by epitaxial growth of two-to-six monolayers (MLs) of shell materials

RECIST vs. Volume Measurement in Medical CT Using Ellipsoids of Known Size

April 12, 2010
Author(s)
Zachary H. Levine, Bruce R. Borchardt, Nolan J. Brandenburg, Charles W. Clark, Balasubramanian Muralikrishnan, Craig M. Shakarji, Joseph J. Chen, Eliot L. Siegel
(a) Purpose: We wanted to test the extent to which two common methods of determining the sizes of tumors would perform when compared to a statistically significant number of well-characterized reference objects. The size of the objects was chosen to

Multimodal, Nanoscale, Hyperspectral Imaging Demonstrated on Heterostructures of Quantum Dots and DNA-Wrapped Single-Wall Carbon Nanotubes

October 21, 2009
Author(s)
Hyeong G. Kang, Matthew L. Clarke, Jianyong Tang, John T. Woodward IV, Shin G. Chou, Zhenping Zhou, Angela R. Hight Walker, Tinh Nguyen, Jeeseong Hwang
A multimodality imaging technique integrating atomic force, polarized Raman, and fluorescence lifetime microscopy and a 2D autocorrelation image analysis is applied to study the properties of a mesoscopic heterostucture of nanoscale materials. This

Structural Basis of Pathway-Dependent Force Profiles in DNA

October 21, 2009
Author(s)
Daniel R. Roe, Anne M. Chaka
Understanding the mechanical properties that guide the flexibility of DNA is important, as DNA must bend and/or stretch in order to function biologically. In addition, there is interest in using DNA as a nanoscopic length and force standard. Over the past

Generation and Mixing of Subfemtoliter Aqueous Droplets on Demand

August 27, 2009
Author(s)
Kristian Helmerson, Jianyong N. Tang, Ana Jofre, Rani Kishore, Joseph E. Reiner, Mark E. Greene, Geoffrey M. Lowman, John Denker, Christina N. Willis, Lori Goldner
We describe a novel method of generating monodisperse sub-femtoliter aqueous droplets on demand by means of piezoelectric injection. Droplets with volumes down to 200 aL are generated by this technique. The droplets are injected into a low refractive index
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