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Detection of Brodifacoum and other Rodenticides in Drug Mixtures using Thermal Desorption Direct Analysis in Real Time Mass Spectrometry (TD-DART-MS)

November 21, 2018

Author(s)

Liz Robinson, Edward Sisco

In recent months, there has been increased reporting of seized drug and toxicology cases containing rodenticides, or superwarfarins, the active ingredient in rat and rodent poisons. While brodifacoum has been the most commonly encountered compound, several

A Method for Measuring the Quantity of Drugs on Surfaces in a Forensic Laboratory

September 19, 2018

Author(s)

Edward R. Sisco, Marcela N. Najarro, Amber Burns

While background studies have been commonplace in many occupational fields for a long time, attempts to understand the chemical background in forensics labs has been largely understudied. However, given the increasing sensitivity of instrumentation and

Strategies and Considerations for the Trace Detection of Fentalogs

October 26, 2017

Author(s)

Edward Sisco

Fentanyl and fentanyl analogs pose a significant and ever changing threat in the United States as both pure compounds and in complex mixtures. While commonly considered detection techniques require visible amounts of powder (i.e. color tests or GC/MS

Report from the Standards for Pathogen Identification via Next-Generation Sequencing (SPIN) Workshop

December 1, 2015

Author(s)

Nathanael Olson, Scott Jackson, Nancy Lin

Next-generation sequencing (NGS) is not routinely used in applied settings due to lack of confidence in results. This workshop convened experts to identify measurement challenges impeding NGS implementation and potential standards-based solutions to

Best Practices for Evaluating Single Nucleotide Variant Calling Methods for Microbial Genomics

July 7, 2015

Author(s)

Nathanael D. Olson, Steven P. Lund, Rebecca Colman, Jeffery T. Foster, Jason W. Sahl, James M. Schupp, Paul Keim, Jayne B. Morrow, Marc L. Salit, Justin M. Zook

Innovations in sequencing technologies have allowed biologists to make incredible advances in understanding biological systems. As experience grows, researchers increasingly recognize that analyzing the wealth of data provided by these new sequencing

Best Practices for Sample Collection and Transport in an Initial Response to Potential Biothreat Materials

March 5, 2014

Author(s)

Jayne B. Morrow, Autumn S. Downey, Lisa Delaney

In the event of a suspected or confirmed biological threat, public safety, law enforcement and public and environmental health authorities may collect samples to support their operational objectives. Initial response to a suspected biothreat should be

An imaging spectrometer based on high resolution microscopy of fluorescent aluminum oxide

January 14, 2013

Author(s)

James A. Bartz, Cynthia J. Zeissler, V. V. Fomenko, Mark S. Akselrod

Fluorescent Nuclear Track Detector (FNTD) technology was tested as an imaging and spectroscopic tool for radionuclide analysis. This investigation intended to distinguish between characteristic α-particles of 239Pu (5.2 MeV), 234U (4.8 MeV) and 238U (4.2

Framework for the Evaluation of DNA Extract Suitability for Identification, Quantification and Sequencing of Unknown Microorganisms Microorganisms

December 3, 2012

Author(s)

Nathanael David Olson, Jayne D. Morrow

This study provides an evaluation of DNA extraction methods when tasked with identifying unknown microorganisms. Research, public health, and clinical laboratories frequently turn to DNA-based molecular methods to identify and quantify unknown

Electrochemical Inactivation of Bacillus Spores in Water Using a Quaternary Oxide Electrode

November 1, 2011

Author(s)

Vytautas Reipa, Andrea Giovannozzi, Jamie L. Almeida, Kenneth D. Cole

Bacillus thuringiensis (BT) spores and B. anthracis Sterne (BA) spores were used to investigate the effectiveness of electrochemical disinfection processes using different solution and operational conditions. We tested several anode materials for

Development and Demonstration of a Method to Evaluate Bio-Sampling Strategies Using Building Simulation and Sample Planning Software

June 10, 2010

Author(s)

William S. Dols, Jayne B. Morrow, Andrew K. Persily, Brett Matzke, Landon Sego, Lisa Nuffer, Brent Pulsipher

response and recovery sampling approaches and technologies, the U.S. Department of Homeland Security (DHS), along with several other agencies, have simulated a biothreat agent release within a facility at Idaho National Laboratory (INL) on two separate

Trace Headspace Sampling for Quantitative Analysis of Explosives with Cryoadsorption on Short Alumina PLOT Columns

June 10, 2010

Author(s)

Tara Lovestead, Thomas J. Bruno

Bombings and the continuous emergence of new and novel explosive compounds necessitate the need for reliable explosive detection devices. Vapor detection methods for sampling and detecting energetic materials or improvised explosive devices (IEDs) are most

Guide for the Selection of Biological Agent Detection Equipment for Emergency First Responders

March 1, 2007

Author(s)

Alim A. Fatah, Richard D. Arcilesi, Tesema Chekol, Charlotte H. Lattin

In recognizing the needs of state and local emergency first responders, the Office of Law Enforcement Standards (OLES) at NIST is developing biological detection equipment guides, through funding provided by the Department of Homeland Security (DHS). This

Test Protocol for Comparative Evaluation of Protective Gloves for Law Enforcement and Corrections Applications

June 1, 1999

Author(s)

Alim A. Fatah, Kathleen M. Higgins

The purpose of this test protocol is to compare the performance of protective gloves for use by law enforcement, corrections, and military personnel. The scope of this test protocol is limited to the types of gloves that meet the rating levels described in