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Forensic Science

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Displaying 1 - 25 of 528

Validation in Forensic Science: Guiding Principles for the Collection and Use of Validation Data

December 12, 2025
Author(s)
Henry Swofford, Steven Lund, Barbara Guttman, Erica Romsos, Johannes Soons, Melissa Taylor, Hariharan Iyer, Peter Vallone, John Jones, Vincent Desiderio, John Butler, Sandra Koch, Robert Thompson, Gregory Fiumara, Edward Sisco, Kelly Sauerwein, Allison Getz, Robert Ramotowski
This document provides guidance to the forensic science community on method validation. Building on the definition of validation in ISO/IEC 17025, it explores the specific components of validation within a forensic science context and introduces five

Evidence Management Steering Committee Report: Expanded Bibliography

September 26, 2025
Author(s)
NIST/NIJ Evidence Management Steering Committee
In 2018 in conjunction with the National Institute of Justice (NIJ), the National Institute of Standards and Technology (NIST) assembled a group of multidisciplinary experts, the Evidence Management Steering Committee (EMSC), to develop a plan to (1)

Report on the May 2025 NIST Measurement Week: Realization of an OSAC draft Interim Performance Assessment for Terrestrial Laser Scanners Used by Law Enforcement Agencies

September 17, 2025
Author(s)
Balasubramanian Muralikrishnan, Katharine Shilling, Mary Gregg, Vincent Lee, Jason Keller, Erin Casey, Eugene Liscio, Bryon O'Neil, Mike Russ, Toby Terpstra
This report describes a terrestrial laser scanner (TLS) testing event, the NIST Measurement Week, held at the National Institute of Standards and Technology (NIST) during the week of May 12-16, 2025. The Crime Scene Investigation and Reconstruction (CSIR)

2024 NIST GenAI (Pilot Study): Text-to-Text Evaluation Overview and Results

June 25, 2025
Author(s)
Hariharan Iyer, Seungmin Seo, Lukas Diduch, Kay Peterson, George Awad, Yooyoung Lee
The 2024 NIST Generative AI (GenAI) Pilot Study focuses on evaluating text-to-text (T2T) generation and discrimination tasks to assess the capabilities and limitations of generative AI models and AI detectors. The study aims to measure the effectiveness of

Implications of the Bullet Black Box Study

June 5, 2025
Author(s)
Bullet Black Box Working Group
The Bullet Black Box Working Group (BulletBB-WG) was convened to review the results of the NIST-Noblis Bullet Black Box Study, and assess the implications of that study on casework. This report includes the recommendations of the BulletBB-WG on how to

The Development of Standards for the Ethical Use of Human Skeletal Remains for Education, Research, and Training in Forensic Anthropology

March 19, 2025
Author(s)
Nicholas Passalacqua, Eric Bartelink, Wendy McQuade, Dawnie Steadman, Donna Boyd, Kate Spradley, Kelly Sauerwein, Ranee Ho
We present a proposed standard regarding the use of contemporary human skeletal remains in education, training, and research contexts in forensic anthropology. This document was generated by the Anthropology subcommittee of the Organization of Scientific

Development of Publicly Available Forensic DNA Sequence Mixture Data

March 12, 2025
Author(s)
Erica Romsos, Kevin Kiesler, Carolyn Steffen, Lisa Borsuk, Sarah Riman, Lauren Mullen, Jodi Irwin, Peter Vallone, Katherine Gettings
Background: In 2018, the Next-Generation Sequencing Committee of SWGDAM queried bioinformatic and statistical interpretation method developers regarding data needs for the development of sequence-based probabilistic genotyping software. Methods: Based on

Novel probabilistic similarity scores for sets of replicate EI mass spectra

March 5, 2025
Author(s)
Amudhan Krishnaswamy Usha, Briana Capistran, Anthony Kearsley
Abstract: Background: Mass spectra are common signatures used to discriminate between compounds. This often involves the use of a similarity score to classify and distinguish between spectra of different compounds. To separate spectra of structurally

UV Stabilizer BTMPS in the Illicit Fentanyl Supply in 9 US Locations

February 5, 2025
Author(s)
Chelsea Shover, Morgan Godvin, Meghan Appley, Elise Pyfrom, Fernando Montero Castrillo, Karli Hochstatter, Neil Garg, Adam Koncsol, Joseph Friedman, Caitlin Molina, Ruby Romero, Brendan Harshberger, Jordan Spoliansky, Candace Winstead, Edward Sisco
Bis(2,2,6,6-tetramethyl-4-piperidyl) sebacate (BTMPS) belongs to a class of molecules called hindered amine light stabilizers that are used in plastics manufacturing and as adhesives or sealants.1 BTMPS has not been studied in humans or approved for human

RaDAR Sample Collection Resources

January 21, 2025
Author(s)
Edward Sisco
This entry contains slides and videos that are intended to posted on the RaDAR website to provide RaDAR collaborators with easy access with sample collection resources.

DNA Mixture Interpretation: A NIST Scientific Foundation Review

December 18, 2024
Author(s)
John Butler, Hariharan Iyer, Richard Press, Melissa Taylor, Peter Vallone, Sheila Willis
Improvements in DNA testing methods have allowed forensic scientists to reduce the quantity of DNA required for profiling an individual. Today, DNA profiles can be generated from a few skin cells. This increased sensitivity has extended the usefulness of
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