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Forensic science

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Displaying 1 - 25 of 547

INTERPOL Review of Forensic Biology and DNA, 2023-2025

June 14, 2026
Author(s)
John Butler
As a part of the 21st INTERPOL International Forensic Science Managers Symposium, this work explores the latest scientific developments, methodologies, and trends in forensic biology and forensic DNA analysis of biological evidence during the years 2023 to

Variant Allele Characterization in STR Markers Using Next Generation Sequencing

May 29, 2026
Author(s)
Lauren Mullen, Carolyn Steffen, Katherine Gettings, Kevin Kiesler, Peter Vallone
Traditionally, Sanger sequencing was used to characterize reference materials and confirm discordant allele calls from different STR typing kits at the National Institute of Standards and Technology (NIST). Sequencing can also identify genomic variations

Developmental Validation of the PowerPlex(R) 18E System: An 8-Dye STR Multiplex for Human Identification Applications

April 28, 2026
Author(s)
Jonelle Thompson, Michael Lauck, Elizabeth Hamilton, Heather Hodges, Maximilian Neis, Cornelius Courts, Aimee Hack, Alan Pierce, David Moore, Katja Anslinger, Birgit Bayer, Peter Vallone, Carolyn Steffen, Rachel Knoener, Karthika Karthika Divakaran, Stephen McDaniel, Robert McLaren
The PowerPlex® 18E System is an 18-locus, eight-dye, STR multiplex optimized for use with the Spectrum CE System and Spectrum Compact CE System. It simultaneously amplifies all 16 ENFSI-recommended loci and two gender-determining loci. In addition, there

A Quantitative Method to Assess DNA Extraction Efficiency

March 15, 2026
Author(s)
Lauren Mullen, Erica Romsos, Peter Vallone
A minimum amount of extracted and purified DNA is required for a forensic short tandem repeat (STR) DNA profile to be obtained from biological samples. In most cases, this amount ranges from 0.5 to 1.0 nanograms. Certain sample types encountered in

Toward a documentary standard for performance testing of terrestrial laser scanners used in forensic practice: A statistical procedure to assess change in instrument precision

January 7, 2026
Author(s)
Mary Gregg, Balasubramanian Muralikrishnan, Katharine Shilling
This paper documents efforts by members of the Crime Scene Investigation and Reconstruction subcommittee within the Organization of Scientific Area Committees for Forensic Science, in collaboration with researchers at the National Institute of Standards

An In-depth Study Evaluating the Determination of CBD, D9-THC, D8-THC, and 25 Additional Cannabinoids in Cannabis Concentrates by Liquid Chromatography with Absorbance Detection

December 15, 2025
Author(s)
Walter Wilson, Arianna Romares, STEPHEN GOLDMAN
Cannabis revenue has risen in the United States (US) from $16.5B in 2018 to $45.4B in 2025 [1], which can be attributed to the legalization of hemp in 2018 with the passage of the Agricultural Improvement Act of 2018 (2018 Farm Bill) and the surge of

Validation in Forensic Science: Guiding Principles for the Collection and Use of Validation Data

December 12, 2025
Author(s)
Henry Swofford, Steven Lund, Barbara Guttman, Erica Romsos, Johannes Soons, Melissa Taylor, Hariharan Iyer, Peter Vallone, John Jones, Vincent Desiderio, John Butler, Sandra Koch, Robert Thompson, Gregory Fiumara, Edward Sisco, Kelly Sauerwein, Allison Getz, Robert Ramotowski
This document provides guidance to the forensic science community on method validation. Building on the definition of validation in ISO/IEC 17025, it explores the specific components of validation within a forensic science context and introduces five

Evidence Management Steering Committee Report: Expanded Bibliography

September 26, 2025
Author(s)
NIST/NIJ Evidence Management Steering Committee
In 2018 in conjunction with the National Institute of Justice (NIJ), the National Institute of Standards and Technology (NIST) assembled a group of multidisciplinary experts, the Evidence Management Steering Committee (EMSC), to develop a plan to (1)

Report on the May 2025 NIST Measurement Week: Realization of an OSAC draft Interim Performance Assessment for Terrestrial Laser Scanners Used by Law Enforcement Agencies

September 17, 2025
Author(s)
Balasubramanian Muralikrishnan, Katharine Shilling, Mary Gregg, Vincent Lee, Jason Keller, Erin Casey, Eugene Liscio, Bryon O'Neil, Mike Russ, Toby Terpstra
This report describes a terrestrial laser scanner (TLS) testing event, the NIST Measurement Week, held at the National Institute of Standards and Technology (NIST) during the week of May 12-16, 2025. The Crime Scene Investigation and Reconstruction (CSIR)

2024 NIST GenAI (Pilot Study): Text-to-Text Evaluation Overview and Results

June 25, 2025
Author(s)
Hariharan Iyer, Seungmin Seo, Lukas Diduch, Kay Peterson, George Awad, Yooyoung Lee
The 2024 NIST Generative AI (GenAI) Pilot Study focuses on evaluating text-to-text (T2T) generation and discrimination tasks to assess the capabilities and limitations of generative AI models and AI detectors. The study aims to measure the effectiveness of
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