Mention has already been made, in Section 5.1. Of the use of DNA-based techniques for control of microbiological DNA. In parallel to the work of ATCC the USA National Institute of Standards and Technology (NIST) developed three Standard Reference Materials (SRM 2390, SRM 2391 and SRM 2392) to provide quality assurance in the analysis of human DNA. Two of these SRMs- the DNA Profiling SRM 2390 and the PCR-based DNA Profiling SRM 2391, are intended for use in forensic and Parternity identifications. For instructional law enforcement, or non-clincal research purposes. They are not intended for any human/animal clinical diagnostic use. The third NIST SRM - 2392 - is for standardization and quality control when sequencing the entire or any segment of human mitochondrial DNA (16 569 base pairs) for forensic identification, disease diagnosis or mutation detection.
Citation: Reference Materials for DNA Analysis
Publisher Info: Book Chapter - Reference Materials for Chemical Analysis - Certification, Availability & Proper Use, Weinheim, NY
Pub Type: Books
DNA, forensic, human, mitochondrial DNA, polymerase Chain Reaction (PCR), restriction fragment length polymorphism, sequencing, short tanem repeats (STR), Standard Reference Materials