Particle size characterization is of particular importance to nanomedicine as nano is a dimensional definition, and the size similarity of nanoparticles to biological moieties is believed to impart many of their unique medical properties. Here we present a method for sample preparation and the determination of mean nanoparticle size (hydrodynamic diameter) using batch-mode dynamic light scattering (DLS) in dilute aqueous suspensions. We then demonstrate this method for 30 nm colloidal gold.
Citation: Characterization of Nanoparticles Intended for Clinical Applications
Publisher Info: Humana Press, Totowa, NJ
Pub Type: Books
Hydrodynamic size, dynamic light scattering, photon correlation spectroscopy, quasi-elastic light scattering, DLS, PCS, QELS, diffusion, diffusion coefficient, particle size