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Human Plasma Metabolites Measured with Different Liquid Chromatography/Mass Spectrometry (LC/MS) Platforms

Published

Author(s)

Kelly H. Telu, Xinjian Yan, William E. Wallace, Stephen Stein, Yamil Simon

Abstract

Non-targeted global metabolite profiles of Standard Reference Material 1950, "Metabolites in Human Plasma," were obtained on five different liquid chromatography/mass spectrometry (LC/MS) instrument combinations using identically prepared samples. Different instruments rendered significantly different metabolite profiles, however, the results were highly reproducible when working with one instrument. The paper describes the raw data that has been made publicly available.
Citation
Journal of Research (NIST JRES) -
Volume
121

Keywords

Global metabolite profiling, Human blood plasma, Non-targeted metabolomics, Standard Reference Material

Citation

Telu, K. , Yan, X. , Wallace, W. , Stein, S. and Simon, Y. (2016), Human Plasma Metabolites Measured with Different Liquid Chromatography/Mass Spectrometry (LC/MS) Platforms, Journal of Research (NIST JRES), National Institute of Standards and Technology, Gaithersburg, MD, [online], https://doi.org/10.6028/jres.121.022, https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=921842 (Accessed July 13, 2024)

Issues

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Created September 22, 2016, Updated October 12, 2021