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Mandy Esch (Fed)

Mandy B. Esch is a project leader in the Microsystems and Nanotechnology Division. She received an M.S. in Biology and a Ph.D. in Biotechnology from the Julius Maximilians University in Würzburg, Germany. During her PhD research she developed paper-based microfluidics and microfluidic biosensors for the detection of pathogens. In 2001, Dr. Esch joined the Cornell Nanoscale Science and Technology Facility as life sciences liaison. In 2007, she joined the department of Biomedical Engineering at Cornell University as a senior research associate. While there, she developed several patents for multi-organ body-on-a-chip systems. As part of a team that develops MPS systems, she received the 2015 Lush Science Prize. From 2015 to 2016 Dr. Esch spent a year as an assistant professor at Syracuse University at the Department of Biomedical and Chemical Engineering. She taught nanobiotechnology and built a laboratory for tissues-on-chip research. In August of 2016 Dr. Esch moved to NIST, where she is focusing on integrating sensors with tissues-on-a-chip and MPS devices.

NRC postdoc opportunities

We are looking for postdocs with expertise in the development of on organs-on-chips, MPS, and PBPK modelling. Please contact Dr. Esch via email, or read about the NRC opportunity here.

Selected Publications


Electron and x-ray focused beam-induced cross-linking in liquids: Toward rapid continuous 3D nanoprinting and interfacing using soft materials

Tanya Gupta, Evgheni Strelcov, Glenn E. Holland, Joshua D. Schumacher, Yang Yang, Mandy B. Esch, Vladimir A. Aksyuk, Patrick Zeller, Matteo Amati, Luca Gregoratti, Andrei A. Kolmakov
Additive fabrication of biocompatible 3D structures out of liquid hydrogel solutions has become pivotal technology for tissue engineering, soft robotics

Biodegradable biliverdin nanoparticles for efficient photoacoustic imaging

Parinaz Fathi, Knox J. Hailay, Dinabandhu Sar, Indu Tripathi, Ostadhossein Fatemeh, Misra K. Santosh, Mandy B. Esch, Jefferson Chan, Dipanjan Pan
Here we report the synthesis of nanoparticles composed of Biliverdin cross-linked with a bifunctional amine functionalized linker. The nanoparticles display
Created September 10, 2019, Updated June 15, 2021