James Alexander Liddle

J. Alexander Liddle is the Chief of the Microsystems and Nanotechnology Division. He received a B.A. and a D. Phil. in Materials Science from the University of Oxford. Alex worked for eleven years at Bell Laboratories, beginning as a postdoctoral researcher and advancing to staff scientist and technical manager. He then spent four years at Lawrence Berkeley National Laboratory in the Center for X-ray Optics, and then as Lead Scientist of the Nanofabrication Facility in the Molecular Foundry. Alex's research at NIST is focused on the physics of self-assembly, where he leads several projects on the measurement of the self-assembly of nanostructures. He holds 16 U.S. patents and has over 250 publications, including several in high profile journals such as Nature and Nano Letters. Alex has also helped organize a number of international conferences and workshops on nanofabrication and self-assembly.

Selected Programs/Projects

• Single Molecule Fluorescence Measurements of Nanoscale Proton Distributions in Photoresist
• DNA Origami for Manufacturing Precise Nanoscale Structures
• Electron Microscopy of Carbon Nanotube Composites
• Directed Self Assembly of Block Copolymers (completed)
• Nanoparticle Tracking for Fluidic Self Assembly (completed)
• Manipulating the Position and Orientation of Nanoparticles using Feedback Control (completed)

Selected Publications

• Quantum-dot fluorescence lifetime engineering with DNA origami constructs, S. H. Ko, K. Du, and J. A. Liddle, Angewandte Chemie International Edition 52, 1193–1197 (2013).
  NIST Publication Database        Journal Web Site
• Quantum dot-DNA origami binding: a single particle, 3D, real-time tracking study, K. Du, S. H. Ko, G. M. Gallatin, H. P. Yoon, J. A. Liddle, and A. J. Berglund, Chemical Communications 49, 907–909 (2013).
  NIST Publication Database        Journal Web Site
• Three-dimensional real-time tracking of nanoparticles at an oil–water interface, K. Du, J. A. Liddle, and A. J. Berglund, Langmuir 28, 9181–9188 (2012).
  NIST Publication Database         Journal Web Site
• Nanomanufacturing with DNA origami: factors affecting the kinetics and yield of quantum dot binding, S. H. Ko, G. M. Gallatin, and J. A. Liddle, Advanced Functional Materials 22, 1015-1023 (2012).
  NIST Publication Database        Journal Web Site
• Lithography, metrology and nanomanufacturing, J. A. Liddle and G. M. Gallatin, Nanoscale 3, 2679 (2011). 
  NIST Publication Database        Journal Web Site
• Simultaneous positioning and orientation of a single nano-object by flow control: theory and simulations, P. P. Mathai, A. J. Berglund, J. Alexander Liddle, and B. A. Shapiro, New Journal of Physics 13, 013027 (2011).
  NIST Publication Database        Journal Web Site
• Measuring the structure of epitaxially assembled block copolymer domains with soft x-ray diffraction, G. E. Stein, J. A. Liddle, A. L. Aquila, and E. M. Gullikson, Macromolecules 43, 433-441 (2010).
  NIST Publication Database        Journal Web Site