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Craig Copeland (Fed)

Craig Copeland is a Research Scientist in the Microsystems & Nanotechnology Division. He received a B.S. in Physics from the University of Maryland, Baltimore County and an M.A. and Ph.D. in Physics from The Johns Hopkins University. At Johns Hopkins, he developed devices and methods for applying and measuring forces in single-cell systems. His current research focuses on the design and characterization of reference materials and calibration methods for localization microscopy, and developing measurement methods for microelectromechanical systems, nanofabrication processes, nanoparticle characterization, and cancer diagnostics.

Selected Publications

  • Heterotypic cell pair co-culturing on patterned microarrays, E. J. Felton, C. R. Copeland, C. S. Chen, and D. H. Reich, Lab on a Chip 12, 3117–3126 (2012).
  • Mechanical Coupling Between Myofibroblasts and Cardiomyocytes Slows Electric Conduction in Fibrotic Cell Monolayers, S. A. Thompson, C. R. Copeland, D. H. Reich, and L. Tung, Circulation 123, 2083–U71 (2011).


Sub-picoliter Traceability of Microdroplet Gravimetry and Microscopy

Lindsay C. C. Elliott, Adam L. Pintar, Craig R. Copeland, Thomas Brian Renegar, Ronald G. Dixson, Robert Ilic, R. Michael Verkouteren, Samuel M. Stavis
Volumetric analysis of single microdroplets is difficult to perform by ensemble gravimetry, whereas optical microscopy is often inaccurate beyond the resolution

Patents (2018-Present)

Patent description for Critical-Dimension Localization Microscopy

Apparatus for Critical-Dimension Localization Microscopy

NIST Inventors
Samuel M. Stavis and Craig Copeland
Performing critical-dimension localization microscopy includes: subjecting a first dimensional member and a second dimensional member of a reference artifact to critical-dimension metrology, the first and second dimensional members, in combination, including a critical dimension and each
Diagram of cells and other components within a blood vessel

Measuring a size distribution of nucleic acid molecules in a sample

NIST Inventors
Craig Copeland and Samuel M. Stavis
A process for measuring a size distribution of a plurality of nucleic acid molecules, the process comprising: labeling the nucleic acid molecules with a fluorescent dye comprising a plurality of fluorescent dye molecules to form labeled nucleic acid molecules, such that a number of fluorescent dyes
Created February 26, 2019, Updated December 8, 2022