Agenda: Standards for Pathogen Detection

Time

Item

8:00 AM

Arrival, Registration, Poster Set-up, Exhibitor Set-up

9:00 AM

Welcome: Scott Jackson NIST
Opening Remarks: Laurie Locascio Director, Material Measurement Laboratory, NIST

9:20 AM

KEYNOTE ADDRESS: RITA R. COLWELL, Ph.D., Distinguished Professor, University of Maryland College Park and Johns Hopkins University Bloomberg School of Public Health
Application of Next Generation Sequencing and Bioinformatics for Rapid and Accurate Pathogen Detection and Characterization

10:10 AM

Jonathan Jacobs MRIGlobal
Culture-Independent Detection and Characterization of Infectious Agents Directly from Clinical and Environmental Sources: A Plea for Standards and Benchmarks

10:35 AM

Morning Break and Poster Viewing

11:05 AM

Lightning Talks (five minutes each)

• Timothy Mercer Garvan, “Synthetic microbial communities provide internal reference standards for metagenome sequencing and analysis”
• Marc Allard FDA CFSAN ORS, “GenomeTrakr database: WGS network for foodborne pathogen traceback”
• William Klimke NCBI, “NCBI Pathogen Detection: Facilitating Traceback and Outbreak Investigation of Pathogen Genome Sequences in Real-Time Using an Automated SNP Clustering Analysis Pipeline”
• Ruth Timme FDA, “Bacterial benchmark datasets for comparison and validation of phylogenomic pipelines”

11:30 AM

Robert Schlaberg  University of Utah School of Medicine
Metagenomics-Based Detection of Respiratory Pathogens in Routine Practice

11:55 AM

Vikram Munikoti DHS
A Standards-Driven Approach to the Deployment of BioWatch Detection Technologies

12:20 PM

Alexa McIntyre Cornell University
Comprehensive Benchmarking and Ensemble Approaches for Metagenomic Classifiers: Short and Long Reads

12:45 PM

Lunch (available for purchase at the NIST cafeteria)

1:50 PM

Lightning Talks (five minutes each)

• Nadim Ajami Baylor College of Medicine, “VirMAP, a viral metagenomics analysis platform for virus taxonomic classification”
• James Pettengill FDA, CFSAN, OAO, “Segal's Law, 16S rRNA gene sequencing, and the perils of foodborne pathogen detection within the American Gut Project”
• Peter Thielen JHU Applied Physics Laboratory, “Optimization of High Throughput Total RNA Sequencing for Acute Encephalitis Diagnostics”

2:10 PM

Jason Kralj NIST

The Mixed Microbial DNA Reference Material for Pathogen Detection

2:35 PM

Nancy Lin NIST

Yeast Cells as a Candidate Reference Material to Support Training in On-Site Biological Agent Sampling and Detection

3:00 PM

Scott Tighe ABRF Metagenomics Research Group

Technical Strategies for Oxford Nanopore Sequencing and Rapid Pathogen Detection and Bio-surveillance

3:25 PM

Afternoon Break and Poster Viewing

3:55 PM

Scott Jackson NIST

Initial Results from The Metagenomic MVP Challenge: An Interlab Study Designed to Assess Bias Associated with Library Preparation Methods and NGS Platforms

4:20 PM

Panel Discussion

5:20 PM

Closing Remarks

5:30 PM

Adjourn

Time

Item

8:00 AM

Arrival/Registration

8:30 AM

Opening Remarks

8:40 AM

Charles Chiu UCSF School of Medicine

Control Materials for Metagenomic Next-Generation Sequencing Assays

9:05 AM

Heike Sichtig US Food and Drug Administration

FDA’s Role in Building the ID NGS Diagnostic Toolkit

9:30 AM

Shanmuga Sozhamannan DBPAO
Next Gen Sequencing Based Biodefense Assays: The Need for Standardized Alternate Reference Materials

9:55 AM

Instructions for Break-out Sessions

10:10 AM

Morning Break and Poster Viewing

10:40 AM

Break-out Session 1

11:30 AM

Move to next session

11:40 AM

Break-out Session 2

12:30 PM

Lunch (available for purchase at the NIST cafeteria)

1:30 PM

Reports from Break-out Sessions

3:15 PM

Closing Remarks

3:30 PM

Adjourn