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Bioscience

Bioimaging

The Research

Chain orientation of polyethylene by polarization BCARS

3D Molecular Orientation Imaging

Ongoing
We have developed 3D orientation measurement techniques by analyzing polarization-dependent molecular vibrational signals based on infrared (IR) absorption [1,2] and coherent anti-Stokes Raman scattering (CARS) [3]. The two imaging modalities are complementary to each other: IR imaging broadly

Advanced Spectral Analysis: Two-Dimensional Correlation Spectroscopy (2DCOS)

Ongoing
When a series of spectra are acquired from a sample as a function of temperature, pressure, electric field strength, concentration, or any experimental parameters, conventional spectral analysis is performed by monitoring the intensity change at a specific frequency. However, such a single frequency
Streptococcus mutans

Biofilm Models to Evaluate Structure-Function Relationships

Ongoing
Biofilms are complex 3D microbial structures that exist throughout nature including on our skin and gut mucosa, in waterways, and in soil. They are typically composed of multiple microbial species surrounded by proteins, polysaccharides, and extracellular DNA woven together into a hydrated matrix

Bioprocessing Laboratory

Ongoing
Current Capabilities Computer controlled liquid nitrogen biostorage system Two culture areas including 4 monitored CO2 incubators 2 Six-foot BSLII biosafety cabinets Measurements- cell count and concentration, STR typing, flow cytometry, cell volume size distribution, conventional transmission and

News and Updates

A hand in a purple glove turns a metal dial on a plate holding tiny vials of purple liquid.

NIST Develops New Nondestructive Method for Assessing Bioengineered Artificial Tissues

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A Recap of TMAP

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NIST Scientists and Engineers Pitch Innovations to Venture Capitalists

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Blog Posts

Leroy Jia poses smiling at his desk, with piles of books in the background.

Mathematical Models Can Help Us Understand — and Possibly Treat — Complex Diseases 

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A spherical, spiky virus is approached on all sides by Y-shaped antibodies.

You Don’t Learn This in School: My Experience as a NIST Summer Intern

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Robotic Motion and Drug-Carrying Nanoparticles: A Look at Two Paths Through the Diverse World of Manufacturing Research

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View bioimaging publications
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