Bioimaging

Automated Live Cell Imaging for Quantification of Catalytic Rates in Individual Cells

Completed

In this study, the rates at which large numbers of individual living cells enzymatically degrade green fluorescent protein (GFP) was examined using automated fluorescence microscopy. A clonal population of NIH3T3 fibroblasts that resulted from stable transfection with a construct containing the

Comparing the Biological Responses of Photoluminescent Silicon Nanoparticles with Silicon Micron-sized Particles

Completed

Intended Impact Technology is now available to produce nanoparticles of uniform size and shape which may allow their use in a wide range of applications from drug delivery to water purification. The high surface area to volume ratio of nanoparticles makes them particularly good catalysts as well as

This figure shows a microscopic image of a field of cells, some of which are pseudocolored red to indicate that these cells remain pluripotent.

Stem Cell Metrology: WSDOM

Ongoing

Stem cells are critical starting materials for advanced therapies and diagnostic devices. The most commonly used are induced pluripotent stem cells (iPSCs) which can be created with any individual’s skin cells, and then can be coaxed to become cells for any tissue of the body. Therapies and

Fluorescence Microscopy Benchmarking: Overview

Completed

A challenge in using microscopy is how to compare and validate data from different instruments, and how to determine that the microscope performance today is the same as yesterday. NIST is developing a practical, automated approach to implementing performance benchmarking methods that will

News and Updates

A hand in a purple glove turns a metal dial on a plate holding tiny vials of purple liquid.

Bioimaging

The Research

Automated Live Cell Imaging for Quantification of Catalytic Rates in Individual Cells

Comparing the Biological Responses of Photoluminescent Silicon Nanoparticles with Silicon Micron-sized Particles

Stem Cell Metrology: WSDOM

Fluorescence Microscopy Benchmarking: Overview

News and Updates

NIST Develops New Nondestructive Method for Assessing Bioengineered Artificial Tissues

Stem Cells and AI: Better Together