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RNA synthetic biology and transcriptomics

Modeling toehold mediated strand exchange circuits across environments and applications

Originally developed for DNA nanotechnology, toehold-mediated strand exchange (TMSE) circuits are now gaining traction in synthetic biology. The Cellular

An engineered bacterial sensor is placed in a contaminated pond containing PFAS. RNA circuits in the bacterial chassis measure PFAS-specific RNA signatures. The bacterial sensor turns pink in response to the presence of PFAS.

Engineering Living Measurement Systems to Sense PFAS

The Cellular Engineering Group is working to engineer components of living cells to sense environmental fluctuations induced by contaminants within their

RNA Computation and Metrology for Engineering Biology

RNA is an increasingly attractive molecule for engineering biology, in part due to the sequence-programmable nature of RNA:RNA interactions. The Cellular

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