Long-term studies of nanoparticle-cell interactions require an advanced tissue-like environment in which nanoparticles are encapsulated with a population of cells for real-time and end-point analysis. By using soft tissue-mimicking hydrogels, the cells are provided with an environment that promotes normal cell function during prolonged nanoparticle exposure. PC12 cells in Collagen I and PEG 4600 hydrogels are considered here, with quantum dots as the model nanoparticle.
Proceedings Title: Proceedings of the 2010 Annual Meeting and Exposition of the Society for Biomaterials
Conference Dates: April 21-24, 2010
Conference Location: Seattle, WA
Conference Title: 2010 Annual Meeting and Exposition of the Society for Biomaterials
Pub Type: Conferences