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Synthesis of Thiol-Clickable and Block Copolypeptide Brushes via Nickel-Mediated Surface Initiated Polymerization of alpha-Amino Acid N-Carboxyanhydrides (NCAs)

Published

Author(s)

Bradley J. Sparks, Jacob G. Ray, Daniel A. Savin, Christopher Stafford, Derek L. Patton

Abstract

We describe the synthesis of homo-, block, and clickable co-polypeptide brushes from low surface area substrates using nickel-mediated surface-initiated polymerization of alpha-amino N-carboxyanhydrides.
Citation
Chemical Communications
Volume
47
Issue
22

Keywords

polymers, brush, NCA, polymerization, surface

Citation

Sparks, B. , Ray, J. , Savin, D. , Stafford, C. and Patton, D. (2011), Synthesis of Thiol-Clickable and Block Copolypeptide Brushes via Nickel-Mediated Surface Initiated Polymerization of alpha-Amino Acid N-Carboxyanhydrides (NCAs), Chemical Communications, [online], https://tsapps.nist.gov/publication/get_pdf.cfm?pub_id=908226 (Accessed October 18, 2025)

Issues

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Created March 30, 2011, Updated October 12, 2021
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