Skip to main content
U.S. flag

An official website of the United States government

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

Standard Reference Materials to Support Measurement of Fatty Acids



Lane C. Sander, Michele M. Schantz, Katherine E. Sharpless, Stephen A. Wise


The National Institute of Standards and Technology offers a variety of natural-matrix and solution-based Standard Reference Materials (SRMs) that are characterized for fatty acid composition. The natural-matrix SRMs are intended primarily for use as control materials, but other uses include method validation, the development of new analytical methods, and use as a component in achieving traceability of measurements. The use of SRMs to support the measurement of fatty acids is relevant to a broad spectrum of applications including compliance with and accuracy of nutritional labeling, food manufacturing tolerances (e.g., infant formulas), traceability of measurements for food exports, clinical nutritional measurements, and characterization of alternative energy sources (e.g., biodiesel). Currently, nearly 30 SRMs are available with certified, reference, and information values reported for fatty acids. Additional SRMs are under development that will complement these reference materials by providing fatty acid profiles in different types of matrices.
Lipid Technology


analytical methods, AOAC food triangle, biodiesel, fatty acid, food matrix, Standard Reference Material


Sander, L. , Schantz, M. , Sharpless, K. and Wise, S. (2009), Standard Reference Materials to Support Measurement of Fatty Acids, Lipid Technology (Accessed June 14, 2024)


If you have any questions about this publication or are having problems accessing it, please contact

Created April 7, 2009, Updated February 19, 2017