November 21, 2023
      
                  
        
  Author(s)
  Elena  Jelisic,   Nenad  Ivezic,   Boonserm  Kulvatunyou,   Perawit  Charoenwut,   Ana  Nikolov
 
       
            
    
    
        The COVID-19 pandemic has brought the cold chain for bio-pharmaceutical products to the spotlight. To preserve their structure and function, biopharmaceuticals such as cells, proteins and enzymes, RNA molecules, and RNA-based drugs (e.g., mRNA-based COVID