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Displaying 1 - 3 of 3

Single-cell measurement of plasmid copy number and promoter activity

March 5, 2021

Author(s)

Bin Shao, Jayan Rammohan, Daniel Anderson, Nina Alperovich, David J. Ross, Christopher Voigt

We have developed a method to simultaneously count plasmid DNA, RNA transcripts, and protein expression in single living bacteria. From these data, the activity of a promoter in units of RNAP/s can be inferred. This work facilitates the reporting of

Measurements drive progress and opportunities in directed evolution for precise engineering of biological systems

February 9, 2021

Author(s)

Drew S. Tack, Eugenia Romantseva, Peter Tonner, Abe Pressman, Jayan Rammohan, Elizabeth Strychalski

Cyberbiosecurity for biopharmaceutical products

February 8, 2021

Author(s)

Elizabeth Strychalski, Jennifer Mantla, Jayan Rammohan, Eugenia Romantseva, Reid D'Amico, Joel Welch, Leah R. Kauffman, James McCarthy, John E. Schiel, Jeffrey Baker, Kelley Rogers, Kelvin Lee