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Search Publications by: John Butler (Fed)

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Displaying 51 - 75 of 105

Setting standards and developing technology to aid the human identity testing community

April 1, 2006
Author(s)
John M. Butler, Michael D. Coble, Amy E. Decker, David L. Duewer, Carolyn R. Steffen, Margaret C. Kline, Janette W. Redman, Peter Vallone
Our project team at the U.S. National Institute of Standards and Technology (NIST) is funded by the National Institute of Justice (NIJ) to conduct research that benefits the human identity testing community and to create tools that enable forensic DNA

The evaluation of an autosomal SNP 12-plex assay

April 1, 2006
Author(s)
Peter M. Vallone, Amy E. Decker, Michael D. Coble, John M. Butler
SNPs have the potential to play a useful role in human identification testing. Small PCR amplicon sizes associated with SNP typing technologies make SNPs attractive for typing degraded DNA or other low copy number situations. SNP markers can be useful in

Analysis of DNA Single Nucleotide Polymorphisms by Mass Spectrometry

March 17, 2006
Author(s)
Peter Vallone, John Butler
Single nucleotide polymorphisms(SNP) are the most frequent form of DNA sequence variation in the human genome and are becoming increasingly useful as genetic markers for genome mapping studies, medical diagnostics, and human identity testing. The primer

DNA Identifications After the 9/11 World Trade Center Attack

November 18, 2005
Author(s)
Leslie G. Biesecker, Joan E. Bailey-Wilson, Jack Ballantyne, Howard R. Baum, Frederick R. Bieber, Charles Brenner, Bruce Budowle, John M. Butler, George Carmody, P. M. Conneally, Barry Duceman, Arthur Eisenberg, Lisa Forman, Kenneth K. Kidd, Beno? Leclair, Steven Niezgoda, Thomas J. Parsons, Elizabeth Pugh, Robert Shaler, Stephen T. Sherry, Amanda Sozer, Anne Walsh

U.S. Population Data for the Multi-Copy Y-STR Locus DYS464

June 25, 2005
Author(s)
John M. Butler, R Schoske
Population studies are important in forensic science and human identity testing to help demonstrate that STR markers are polymorphic and will help distinguish the various individuals from one another. A total of 679 male DNA samples from 3 U.S. populations

Results From the NIST 2004 DNA Quantitation Study

May 1, 2005
Author(s)
Margaret C. Kline, David L. Duewer, Janette W. Redman, John M. Butler
For optimal DNA Short Tandem Repeat (STR) typing results, the DNA concentration ([DNA]) of the sample must be accurately determined prior to the polymerase chain reaction (PCR) amplification step in the typing process. In early 2004, the National Institute

Mitochondrial DNA Typing Screens With Control Region and Coding Region SNPs

March 1, 2005
Author(s)
Margaret C. Kline, Peter M. Vallone, Janette W. Redman, David L. Duewer, C D. Calloway, John M. Butler
Mitochondrial DNA (mtDNA) analysis has found an important niche in forensic DNA typing. It is used with highly degraded samples or low-copy number materials such as might be found from shed hair or bones exposed to severe environmental conditions. The