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Search Publications by

Mary C. Brady (Ctr)

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Displaying 1 - 25 of 51

Approaches to Training Multi-Class Semantic Image Segmentation of Damage in Concrete

May 14, 2020
Peter Bajcsy, Steven B. Feldman, Michael P. Majurski, Kenneth A. Snyder, Mary C. Brady
This paper addresses the problem of creating a large quantity of high-quality training image segmentation masks from scanning electron microscopy (SEM) images of concrete samples that exhibit progressive amounts of degradation resulting from alkali-silica

Modeling, Validation and Verification of Three-Dimensional Cell-Scaffold Contacts from Terabyte- sized Images

December 1, 2017
Peter Bajcsy, Sowon Joy Yoon, Stephen Florczyk, Nathan Hotaling, Mylene H. Simon, Piotr Szczypinski, Nicholas J. Schaub, Carl G. Simon Jr., Mary C. Brady, Ram D. Sriram
Background: Cell-scaffold contact measurements are derived from pairs of co-registered volumetric fluorescent confocal laser scanning microscopy (CLSM) images (z-stacks) of stained cells and spun coat, large microfiber, and medium microfiber scaffolds. Our

3D Cellular Morphotyping of Cell Niches

August 31, 2017
Stephen J. Florczyk, Mylene H. Simon, Derek Juba, Patrick S. Pine, Sumona Sarkar, Desu Chen, Paula J. Baker, Subhadip Bodhak, Antonio Cardone, Mary C. Brady, Peter Bajcsy, Carl G. Simon Jr.
Three-dimensional (3D) cellular morphotyping is introduced for assessing and comparing the niches provided by biomaterial scaffolds. Many scaffold systems have been advanced to provide synthetic cell niches for tissue engineering and drug screening

A Hybrid Task Graph Scheduler for High Performance Image Processing Workflows

June 22, 2017
Timothy J. Blattner, Walid Keyrouz, Mary C. Brady, Shuvra S. Bhattacharyya, Milton Halem
Designing applications for scalability is key to improving their performance in hybrid and cluster computing. Scheduling code to utilize parallelism is difficult, particularly when dealing with data dependencies, memory management, data motion, and

From Image Tiles to Web-Based Interactive Measurements in One Stop

January 4, 2017
Antoine Vandecreme, Michael P. Majurski, Joe Chalfoun, Keana Scott, John Henry Scott, Mary C. Brady, Peter Bajcsy
This article aims at introducing readers to a web-based solution useful for interactive measurements of centimeter-sized specimens at nanoscales. Modern imaging technology has enabled nanoscale imaging to become a routine process. As the imaging technology

An Informatics Infrastructure for the Materials Genome Initiative

July 6, 2016
Alden A. Dima, Sunil K. Bhaskarla, Chandler A. Becker, Mary C. Brady, Carelyn E. Campbell, Philippe J. Dessauw, Robert J. Hanisch, Ursula R. Kattner, Kenneth G. Kroenlein, Adele P. Peskin, Raymond L. Plante, Guillaume Sousa Amaral, Zachary T. Trautt, James A. Warren, Sharief S. Youssef, Sheng Yen Li, Pierre Francois Rigodiat, Marcus W. Newrock
A materials data infrastructure that enables the sharing and transformation of a wide range of materials data is an essential part of achieving the goals of the Materials Genome Initiative. We describe two high-level requirements of such an infrastructure

Enabling Interactive Measurements from Large Coverage Microscopy

July 1, 2016
Peter Bajcsy, Antoine Vandecreme, Julien M. Amelot, Mary C. Brady, Joe Chalfoun, Michael P. Majurski
Microscopy could be an important tool for characterizing stem cell products if quantitative measurements could be collected over multiple spatial and temporal scales. With the cells changing states over time and being several orders of magnitude smaller

Methodology for Increasing Image Feature Measurement Accuracy

June 30, 2016
Michael Paul Majurski, Joe Chalfoun, Steven Lund, Peter Bajcsy, Mary C. Brady
Motivation Image features are computed in cell biology to derive quantitative information regarding cell state, differentiation, biological activity, and cell dynamics. The accuracy of any biological conclusions depends on the accuracy of the measured

Acceleration and Parallelization of ZENO/Walk-on-Spheres

June 1, 2016
Derek Juba, Walid Keyrouz, Michael V. Mascagni, Mary C. Brady, Michael Mascagni
This paper describes our on-going work to accelerate ZENO, a software tool based on Monte Carlo methods (MCMs), used for computing material properties at the nanoscale. ZENO employs three main algorithms: (1)Walk on Spheres (WoS), (2)interior sampling, and

3D Segmentation of Stem Cells from Thousands of Confocal Microscopy Images

March 1, 2016
Peter Bajcsy, Mylene H. Simon, Stephen J. Florczyk, Carl G. Simon Jr., Derek Juba, Mary C. Brady
We address the problem of estimating 3D segmentation performance when segmentation is applied to thousands of confocal microscopy images (z-stacks) of cells. With a very large number of z-stacks, manual inputs to validate each segmentation result are

Survey Statistics of Automated Segmentations Applied to Optical Imaging of Mammalian Cells

January 8, 2016
Peter Bajcsy, Antonio Cardone, Joe Chalfoun, Michael W. Halter, Derek Juba, Marcin Kociolek, Michael P. Majurski, Adele P. Peskin, Carl G. Simon Jr., Mylene H. Simon, Antoine Vandecreme, Anne L. Plant, Mary C. Brady
The goal of this survey paper is to overview cellular measurements using optical microscopy imaging followed by automated image segmentation. The cellular measurements of primary interest are taken from mammalian cells and their components. They are

A Hybrid Task Graph Scheduler for High Performance Image Processing Workflows

December 16, 2015
Timothy J. Blattner, Walid Keyrouz, Milton Halem, Shuvra S. Bhattacharyya, Mary C. Brady
The scalability of applications is a key requirement to improving performance in hybrid and cluster computing. Scheduling code to utilize parallelism is difficult, particularly when dealing with dependencies, memory management, data motion, and processor

Shape Descriptors Comparison for Cell Tracking

October 15, 2015
Michael P. Majurski, Christopher Zheng, Joe Chalfoun, Alden A. Dima, Mary C. Brady
New microscope technologies are enabling the acquisition of large volumes of live cell image data. Accurate temporal object tracking is required to facilitate the analysis of this data. One principle component of cell tracking is correspondence, matching

Systematic Measurement of Marginal Mark Types on Voting Ballots

July 24, 2015
Andrea V. Bajcsy, Ya-Shian Li-Baboud, Mary C. Brady
The presence of marginal marks on voting ballots is a ubiquitous problem in voting systems and it is a common source of dispute during federal and state-level elections. As of today, marginal marks are neither clearly countable as votes or as non-votes by

Detection and characterization of nonspecific, sparsely-populated binding modes for conformational selection in the early stages of complexation

March 18, 2015
Antonio Cardone, Aaron Bornstein, Harish C. Pant, Mary C. Brady, Ram D. Sriram, Sergio Hassan
A method is proposed to study protein-ligand binding in a system governed by specific and non-specific interactions. Strong associations lead to narrow conformational distributions in the proteins configuration space; weak and ultra-weak associations lead